PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0216s0040.3.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

bHLH

Protein Properties

Length: 629aa MW: 71926.9 Da PI: 8.489

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0216s0040.3.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	11.5	0.00056	533	569	15	51
HHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHH CS HLH 15 riNsafeeLrellPkaskapskKlsKaeiLekAveYI 51 +iN+ f++Lr+++ ++++ +K+s +++L+ ++ + Kalax.0216s0040.3.p 533 QINTLFANLRRVIISNCQHEYGKVSASMTLRGYIDIL 569 7************889**********9777655 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.1270.60	6.9E-31	21	172	IPR027267	Arfaptin homology (AH) domain/BAR domain
SuperFamily	SSF103657	1.48E-41	21	187	No hit	No description
Pfam	PF16746	1.6E-27	23	182	No hit	No description
Gene3D	G3DSA:2.30.29.30	1.7E-25	185	372	IPR011993	PH domain-like
SuperFamily	SSF50729	6.82E-26	192	273	IPR011993	PH domain-like
SuperFamily	SSF103657	1.48E-41	237	262	No hit	No description
PROSITE profile	PS50003	18.159	239	365	IPR001849	Pleckstrin homology domain
SMART	SM00233	9.0E-21	240	367	IPR001849	Pleckstrin homology domain
Pfam	PF00169	1.2E-14	241	364	IPR001849	Pleckstrin homology domain
CDD	cd13250	1.56E-39	242	369	No hit	No description
SuperFamily	SSF50729	6.82E-26	303	364	IPR011993	PH domain-like
SuperFamily	SSF57863	1.01E-35	430	521	No hit	No description
SMART	SM00105	1.1E-35	431	551	IPR001164	Arf GTPase activating protein
PROSITE profile	PS50115	25.717	431	514	IPR001164	Arf GTPase activating protein
Pfam	PF01412	4.4E-32	433	521	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	4.1E-15	443	462	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	4.1E-15	462	479	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	4.1E-15	485	506	IPR001164	Arf GTPase activating protein

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005737	Cellular Component	cytoplasm
GO:0005096	Molecular Function	GTPase activator activity
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 629 aa Download sequence Send to blast
MSCGVFFMTF VLTHSWPVSS GHIMTKFTGA LREISVYKDG LQSQVEQVLN ERLFNFVNND 60 INDVKEARKR FDKASSLYDQ AREKFLSLRK STRLDVAAGF EEELYRARSR FEQARFNLIG 120 AIYNVETKKK YEFLDAVSGA VAAHLVYFKQ GYELLLQMEP LIEQIAAYTK QSQENFTREK 180 ASLNERMQEY QRQVDQESRP SHENMVDSLR NGDCMQPSSR SSHRLIQAVM QSSSIGKVQI 240 IRQGYLSKRS SNLRGDWKRR YFVLDSRGML YYYRKQWTRS PNAPPEYGSG ILSRWRSSHY 300 HVVHDERTVA RHTVDLLTST IKIDADQTDL RFCFRIISPS KTYTLQAESA TDQMDWIEKI 360 TGVITSLLSS QDHDTRVVNE EDFCFPTEAL TPGSPFYFDS PSSDENGVVA CPGLYQRCRT 420 IQSQSQNTNN EKPINILRKI PGNDICADCG AADPEWASLN LGVLICIECS GVHRNLGVHI 480 SKVRSLTLDV KVWEPSIMTL FGSLGNVYAN SIWEELLNPK SACQYDGMPI SMQINTLFAN 540 LRRVIISNCQ HEYGKVSASM TLRGYIDILL LLKRISMAFT DEYYHVSLQR NYLQTRKKLV 600 IVSNCCLVKG VVGTLYFIWL VNARTLAW*

Sequence ? help Back to Top

Protein Sequence Length: 629 aa Download sequence Send to blast

MSCGVFFMTF VLTHSWPVSS GHIMTKFTGA LREISVYKDG LQSQVEQVLN ERLFNFVNND  60
INDVKEARKR FDKASSLYDQ AREKFLSLRK STRLDVAAGF EEELYRARSR FEQARFNLIG  120
AIYNVETKKK YEFLDAVSGA VAAHLVYFKQ GYELLLQMEP LIEQIAAYTK QSQENFTREK  180
ASLNERMQEY QRQVDQESRP SHENMVDSLR NGDCMQPSSR SSHRLIQAVM QSSSIGKVQI  240
IRQGYLSKRS SNLRGDWKRR YFVLDSRGML YYYRKQWTRS PNAPPEYGSG ILSRWRSSHY  300
HVVHDERTVA RHTVDLLTST IKIDADQTDL RFCFRIISPS KTYTLQAESA TDQMDWIEKI  360
TGVITSLLSS QDHDTRVVNE EDFCFPTEAL TPGSPFYFDS PSSDENGVVA CPGLYQRCRT  420
IQSQSQNTNN EKPINILRKI PGNDICADCG AADPEWASLN LGVLICIECS GVHRNLGVHI  480
SKVRSLTLDV KVWEPSIMTL FGSLGNVYAN SIWEELLNPK SACQYDGMPI SMQINTLFAN  540
LRRVIISNCQ HEYGKVSASM TLRGYIDILL LLKRISMAFT DEYYHVSLQR NYLQTRKKLV  600
IVSNCCLVKG VVGTLYFIWL VNARTLAW*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3jue_A	4e-21	437	514	39	114	ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3jue_B	4e-21	437	514	39	114	ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3t9k_A	4e-21	437	514	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
3t9k_B	4e-21	437	514	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
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Functional Description ? help Back to Top
Source	Description
UniProt	GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in the spatial control of provascular differentiation. Required for the formation of the normal pattern of continuous secondary veins. Involved in auxin signaling but not in polar auxin transport or in auxin responses. Required for PIN1 internalization in roots. {ECO:0000269\|PubMed:10887076, ECO:0000269\|PubMed:10887077, ECO:0000269\|PubMed:15743878, ECO:0000269\|PubMed:16698946}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by auxin. {ECO:0000269\|PubMed:15743878}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010249220.1	0.0	PREDICTED: ADP-ribosylation factor GTPase-activating protein AGD3
Swissprot	Q5W7F2	0.0	AGD3_ARATH; ADP-ribosylation factor GTPase-activating protein AGD3
TrEMBL	A0A1U7ZLB4	0.0	A0A1U7ZLB4_NELNU; ADP-ribosylation factor GTPase-activating protein AGD3
STRING	XP_010249220.1	0.0	(Nelumbo nucifera)

Link Out ? help Back to Top
Phytozome	Kalax.0216s0040.3.p

Publications ? help Back to Top
Koizumi K,Sugiyama M,Fukuda H A series of novel mutants of Arabidopsis thaliana that are defective in the formation of continuous vascular network: calling the auxin signal flow canalization hypothesis into question. Development, 2000. 127(15): p. 3197-204 [PMID:10887076] Vernoud V,Horton AC,Yang Z,Nielsen E Analysis of the small GTPase gene superfamily of Arabidopsis. Plant Physiol., 2003. 131(3): p. 1191-208 [PMID:12644670] Sawa S,Demura T,Horiguchi G,Kubo M,Fukuda H The ATE genes are responsible for repression of transdifferentiation into xylem cells in Arabidopsis. Plant Physiol., 2005. 137(1): p. 141-8 [PMID:15618413] Sawa S, et al. DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis. Plant Physiol., 2005. 138(2): p. 819-26 [PMID:15923323] Sieburth LE, et al. SCARFACE encodes an ARF-GAP that is required for normal auxin efflux and vein patterning in Arabidopsis. Plant Cell, 2006. 18(6): p. 1396-411 [PMID:16698946] Naramoto S, et al. Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants. Development, 2009. 136(9): p. 1529-38 [PMID:19363154] Carland F,Nelson T CVP2- and CVL1-mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns. Plant J., 2009. 59(6): p. 895-907 [PMID:19473324] Naramoto S, et al. ADP-ribosylation factor machinery mediates endocytosis in plant cells. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(50): p. 21890-5 [PMID:21118984] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Prabhakaran Mariyamma N,Hou H,Carland FM,Nelson T,Schultz EA Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion. J. Exp. Bot., 2017. 68(13): p. 3375-3390 [PMID:28575401]