PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0216s0040.4.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

bHLH

Protein Properties

Length: 684aa MW: 78182.9 Da PI: 8.2889

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0216s0040.4.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	11.4	0.00062	588	624	15	51
HHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHH CS HLH 15 riNsafeeLrellPkaskapskKlsKaeiLekAveYI 51 +iN+ f++Lr+++ ++++ +K+s +++L+ ++ + Kalax.0216s0040.4.p 588 QINTLFANLRRVIISNCQHEYGKVSASMTLRGYIDIL 624 7************889**********9777655 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00721	2.0E-9	1	219	IPR004148	BAR domain
Pfam	PF16746	8.2E-39	7	237	No hit	No description
SuperFamily	SSF103657	4.04E-56	7	242	No hit	No description
Gene3D	G3DSA:1.20.1270.60	3.0E-37	13	227	IPR027267	Arfaptin homology (AH) domain/BAR domain
CDD	cd07606	2.50E-84	16	216	No hit	No description
Gene3D	G3DSA:2.30.29.30	2.0E-25	240	427	IPR011993	PH domain-like
SuperFamily	SSF50729	8.13E-26	247	328	IPR011993	PH domain-like
SuperFamily	SSF103657	4.04E-56	292	317	No hit	No description
PROSITE profile	PS50003	18.159	294	420	IPR001849	Pleckstrin homology domain
SMART	SM00233	9.0E-21	295	422	IPR001849	Pleckstrin homology domain
Pfam	PF00169	1.4E-14	296	419	IPR001849	Pleckstrin homology domain
CDD	cd13250	1.85E-39	297	424	No hit	No description
SuperFamily	SSF50729	8.13E-26	358	419	IPR011993	PH domain-like
SuperFamily	SSF57863	1.14E-35	485	576	No hit	No description
PROSITE profile	PS50115	25.717	486	569	IPR001164	Arf GTPase activating protein
SMART	SM00105	1.1E-35	486	606	IPR001164	Arf GTPase activating protein
Pfam	PF01412	5.0E-32	488	576	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	5.1E-15	498	517	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	5.1E-15	517	534	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	5.1E-15	540	561	IPR001164	Arf GTPase activating protein

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005737	Cellular Component	cytoplasm
GO:0005096	Molecular Function	GTPase activator activity
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 684 aa Download sequence Send to blast
MMQFAKLEDS PMFRQQIQNL EEGAEVLRER VLKFYKGCKK YSEGIREGRE IDNQFANAIE 60 AFGGSPIDNI SAAFGGHIMT KFTGALREIS VYKDGLQSQV EQVLNERLFN FVNNDINDVK 120 EARKRFDKAS SLYDQAREKF LSLRKSTRLD VAAGFEEELY RARSRFEQAR FNLIGAIYNV 180 ETKKKYEFLD AVSGAVAAHL VYFKQGYELL LQMEPLIEQI AAYTKQSQEN FTREKASLNE 240 RMQEYQRQVD QESRPSHENM VDSLRNGDCM QPSSRSSHRL IQAVMQSSSI GKVQIIRQGY 300 LSKRSSNLRG DWKRRYFVLD SRGMLYYYRK QWTRSPNAPP EYGSGILSRW RSSHYHVVHD 360 ERTVARHTVD LLTSTIKIDA DQTDLRFCFR IISPSKTYTL QAESATDQMD WIEKITGVIT 420 SLLSSQDHDT RVVNEEDFCF PTEALTPGSP FYFDSPSSDE NGVVACPGLY QRCRTIQSQS 480 QNTNNEKPIN ILRKIPGNDI CADCGAADPE WASLNLGVLI CIECSGVHRN LGVHISKVRS 540 LTLDVKVWEP SIMTLFGSLG NVYANSIWEE LLNPKSACQY DGMPISMQIN TLFANLRRVI 600 ISNCQHEYGK VSASMTLRGY IDILLLLKRI SMAFTDEYYH VSLQRNYLQT RKKLVIVSNC 660 CLVKGVVGTL YFIWLVNART LAW*

Sequence ? help Back to Top

Protein Sequence Length: 684 aa Download sequence Send to blast

MMQFAKLEDS PMFRQQIQNL EEGAEVLRER VLKFYKGCKK YSEGIREGRE IDNQFANAIE  60
AFGGSPIDNI SAAFGGHIMT KFTGALREIS VYKDGLQSQV EQVLNERLFN FVNNDINDVK  120
EARKRFDKAS SLYDQAREKF LSLRKSTRLD VAAGFEEELY RARSRFEQAR FNLIGAIYNV  180
ETKKKYEFLD AVSGAVAAHL VYFKQGYELL LQMEPLIEQI AAYTKQSQEN FTREKASLNE  240
RMQEYQRQVD QESRPSHENM VDSLRNGDCM QPSSRSSHRL IQAVMQSSSI GKVQIIRQGY  300
LSKRSSNLRG DWKRRYFVLD SRGMLYYYRK QWTRSPNAPP EYGSGILSRW RSSHYHVVHD  360
ERTVARHTVD LLTSTIKIDA DQTDLRFCFR IISPSKTYTL QAESATDQMD WIEKITGVIT  420
SLLSSQDHDT RVVNEEDFCF PTEALTPGSP FYFDSPSSDE NGVVACPGLY QRCRTIQSQS  480
QNTNNEKPIN ILRKIPGNDI CADCGAADPE WASLNLGVLI CIECSGVHRN LGVHISKVRS  540
LTLDVKVWEP SIMTLFGSLG NVYANSIWEE LLNPKSACQY DGMPISMQIN TLFANLRRVI  600
ISNCQHEYGK VSASMTLRGY IDILLLLKRI SMAFTDEYYH VSLQRNYLQT RKKLVIVSNC  660
CLVKGVVGTL YFIWLVNART LAW*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3t9k_A	4e-21	492	569	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
3t9k_B	4e-21	492	569	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
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Functional Description ? help Back to Top
Source	Description
UniProt	GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in the spatial control of provascular differentiation. Required for the formation of the normal pattern of continuous secondary veins. Involved in auxin signaling but not in polar auxin transport or in auxin responses. Required for PIN1 internalization in roots. {ECO:0000269\|PubMed:10887076, ECO:0000269\|PubMed:10887077, ECO:0000269\|PubMed:15743878, ECO:0000269\|PubMed:16698946}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by auxin. {ECO:0000269\|PubMed:15743878}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010249220.1	0.0	PREDICTED: ADP-ribosylation factor GTPase-activating protein AGD3
Swissprot	Q5W7F2	0.0	AGD3_ARATH; ADP-ribosylation factor GTPase-activating protein AGD3
TrEMBL	A0A1U7ZLB4	0.0	A0A1U7ZLB4_NELNU; ADP-ribosylation factor GTPase-activating protein AGD3
STRING	XP_010249220.1	0.0	(Nelumbo nucifera)

Link Out ? help Back to Top
Phytozome	Kalax.0216s0040.4.p

Publications ? help Back to Top
Koizumi K,Sugiyama M,Fukuda H A series of novel mutants of Arabidopsis thaliana that are defective in the formation of continuous vascular network: calling the auxin signal flow canalization hypothesis into question. Development, 2000. 127(15): p. 3197-204 [PMID:10887076] Vernoud V,Horton AC,Yang Z,Nielsen E Analysis of the small GTPase gene superfamily of Arabidopsis. Plant Physiol., 2003. 131(3): p. 1191-208 [PMID:12644670] Sawa S,Demura T,Horiguchi G,Kubo M,Fukuda H The ATE genes are responsible for repression of transdifferentiation into xylem cells in Arabidopsis. Plant Physiol., 2005. 137(1): p. 141-8 [PMID:15618413] Sawa S, et al. DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis. Plant Physiol., 2005. 138(2): p. 819-26 [PMID:15923323] Sieburth LE, et al. SCARFACE encodes an ARF-GAP that is required for normal auxin efflux and vein patterning in Arabidopsis. Plant Cell, 2006. 18(6): p. 1396-411 [PMID:16698946] Naramoto S, et al. Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants. Development, 2009. 136(9): p. 1529-38 [PMID:19363154] Carland F,Nelson T CVP2- and CVL1-mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns. Plant J., 2009. 59(6): p. 895-907 [PMID:19473324] Naramoto S, et al. ADP-ribosylation factor machinery mediates endocytosis in plant cells. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(50): p. 21890-5 [PMID:21118984] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Prabhakaran Mariyamma N,Hou H,Carland FM,Nelson T,Schultz EA Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion. J. Exp. Bot., 2017. 68(13): p. 3375-3390 [PMID:28575401]