PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0342s0019.1.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family NAC
Protein Properties Length: 258aa    MW: 29417.1 Da    PI: 6.1589
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0342s0019.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM160.95e-50111461128
                  NAM   1 lppGfrFhPtdeelvveyLkkkvegkk....leleevikevdiykvePwdLp.k....kvkaeekewyfFskrdkkyatgkrknratksg 81 
                          +ppGfrFhPt+eelv +yL+kk++ +     ++  +vi ++d++++ePwd+  k     +++eekewyf+s++ +ky+tg+r+nrat++g
  Kalax.0342s0019.1.p  11 VPPGFRFHPTEEELVGYYLRKKISMNGnideCDYLNVIIDIDLCTMEPWDILgKcsqgGAYEEEKEWYFYSHKGRKYPTGSRTNRATAAG 100
                          69*********************99888777777789**************74445554445889************************* PP

                  NAM  82 yWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                          +Wkatg+dk+vls ++e++g++ktLvfy+grap+g+ktdW++heyrl
  Kalax.0342s0019.1.p 101 FWKATGRDKAVLS-RNEVIGMRKTLVFYHGRAPNGKKTDWIIHEYRL 146
                          *************.999****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019414.05E-555167IPR003441NAC domain
PROSITE profilePS5100554.20111167IPR003441NAC domain
PfamPF023654.2E-2612146IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 258 aa     Download sequence    Send to blast
METLSTSSTC VPPGFRFHPT EEELVGYYLR KKISMNGNID ECDYLNVIID IDLCTMEPWD  60
ILGKCSQGGA YEEEKEWYFY SHKGRKYPTG SRTNRATAAG FWKATGRDKA VLSRNEVIGM  120
RKTLVFYHGR APNGKKTDWI IHEYRLQAYE HGPPQEEGWV VCRAFKKPCP NQQRFSSFLY  180
HADPQVSYTA ITPSVSQQQL HNPSYNFKEY GGCNNQVELV PEIDGSISAK ECLGTDWDQQ  240
LSQLQVFPCN LPFDIDV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A2e-4321738171NO APICAL MERISTEM PROTEIN
1ut4_B2e-4321738171NO APICAL MERISTEM PROTEIN
1ut7_A2e-4321738171NO APICAL MERISTEM PROTEIN
1ut7_B2e-4321738171NO APICAL MERISTEM PROTEIN
3swm_A2e-43217311174NAC domain-containing protein 19
3swm_B2e-43217311174NAC domain-containing protein 19
3swm_C2e-43217311174NAC domain-containing protein 19
3swm_D2e-43217311174NAC domain-containing protein 19
3swp_A2e-43217311174NAC domain-containing protein 19
3swp_B2e-43217311174NAC domain-containing protein 19
3swp_C2e-43217311174NAC domain-containing protein 19
3swp_D2e-43217311174NAC domain-containing protein 19
4dul_A2e-4321738171NAC domain-containing protein 19
4dul_B2e-4321738171NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016675829.17e-90PREDICTED: NAC domain-containing protein 30-like isoform X1
RefseqXP_016704028.14e-90PREDICTED: NAC domain-containing protein 30-like
SwissprotQ9C8W91e-84NAC30_ARATH; NAC domain-containing protein 30
TrEMBLA0A1U8IIX41e-88A0A1U8IIX4_GOSHI; NAC domain-containing protein 30-like isoform X1
TrEMBLA0A1U8KSQ71e-88A0A1U8KSQ7_GOSHI; NAC domain-containing protein 30-like
STRINGGorai.013G140700.17e-89(Gossypium raimondii)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G71930.14e-87vascular related NAC-domain protein 7
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  3. Li Z, et al.
    A Transcriptional and Metabolic Framework for Secondary Wall Formation in Arabidopsis.
    Plant Physiol., 2016. 172(2): p. 1334-1351
    [PMID:27566165]
  4. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  5. Tan TT, et al.
    Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation.
    Plant Physiol., 2018. 176(1): p. 773-789
    [PMID:29133368]
  6. Ohashi-Ito K,Iwamoto K,Fukuda H
    LOB DOMAIN-CONTAINING PROTEIN 15 Positively Regulates Expression of VND7, a Master Regulator of Tracheary Elements.
    Plant Cell Physiol., 2018. 59(5): p. 989-996
    [PMID:29444288]