PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.1691s0002.2.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

bHLH

Protein Properties

Length: 472aa MW: 53858.5 Da PI: 8.1616

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.1691s0002.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	13.1	0.00018	376	413	15	52
HHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHH CS HLH 15 riNsafeeLrellPkaskapskKlsKaeiLekAveYIk 52 +iN+ f++Lr+++ ++++ +K+s +++L+ ++ + Kalax.1691s0002.2.p 376 QINTLFANLRRVIISNCQHEYGKVSASMTLRGCIDILL 413 7************889***********9888766 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF50729	8.13E-25	38	116	IPR011993	PH domain-like
Gene3D	G3DSA:2.30.29.30	7.8E-25	82	216	IPR011993	PH domain-like
PROSITE profile	PS50003	17.229	82	208	IPR001849	Pleckstrin homology domain
SMART	SM00233	9.2E-20	83	210	IPR001849	Pleckstrin homology domain
Pfam	PF00169	5.6E-14	84	207	IPR001849	Pleckstrin homology domain
CDD	cd13250	1.08E-39	85	212	No hit	No description
SuperFamily	SSF50729	8.13E-25	146	207	IPR011993	PH domain-like
SuperFamily	SSF57863	6.41E-36	273	364	No hit	No description
PROSITE profile	PS50115	25.717	274	357	IPR001164	Arf GTPase activating protein
SMART	SM00105	3.1E-36	274	394	IPR001164	Arf GTPase activating protein
Pfam	PF01412	3.1E-32	276	363	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	1.9E-15	286	305	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	1.9E-15	305	322	IPR001164	Arf GTPase activating protein
PRINTS	PR00405	1.9E-15	328	349	IPR001164	Arf GTPase activating protein

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005096	Molecular Function	GTPase activator activity
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 472 aa Download sequence Send to blast
MEPLIEQIAA YTKQSQENFT REKALLNERM QEYQRQVDQE SRPSHENMVD SLRNGDCMQP 60 SSRSSHRLIQ AVMQSSSIGK VQIIRQGYLS KRSSNLRGDW KRRYFVLDSR GMLYYYRKQW 120 TRSPNAPPEY GSGILSRWRS SHYHVVHDER TVARHTVDLL TSTIKIDADQ TDLRFCFRII 180 SPSKTCTLQA ESATDQMDWI EKITGVITSL LSSQDHDTRV VNEEDFCFPT EALTPGRLFY 240 FDSPSSDENG LVACPGLYQK CRTIQSQSQN TNNEKPINIL RKIPGNDICA DCGAADPEWA 300 SLNLGVLICI ECSGVHRNLG VHISKVRSLT LDVKVWEPSI MTLFGSLGNV YANSIWEELL 360 NPKSACQYDG MPFSMQINTL FANLRRVIIS NCQHEYGKVS ASMTLRGCID ILLLLKRISM 420 AFTDEYYHVS LQRNYLQTRK ELVIVSNCCL VKGVVGTLYF IWLVKVRTLA W*

Sequence ? help Back to Top

Protein Sequence Length: 472 aa Download sequence Send to blast

MEPLIEQIAA YTKQSQENFT REKALLNERM QEYQRQVDQE SRPSHENMVD SLRNGDCMQP  60
SSRSSHRLIQ AVMQSSSIGK VQIIRQGYLS KRSSNLRGDW KRRYFVLDSR GMLYYYRKQW  120
TRSPNAPPEY GSGILSRWRS SHYHVVHDER TVARHTVDLL TSTIKIDADQ TDLRFCFRII  180
SPSKTCTLQA ESATDQMDWI EKITGVITSL LSSQDHDTRV VNEEDFCFPT EALTPGRLFY  240
FDSPSSDENG LVACPGLYQK CRTIQSQSQN TNNEKPINIL RKIPGNDICA DCGAADPEWA  300
SLNLGVLICI ECSGVHRNLG VHISKVRSLT LDVKVWEPSI MTLFGSLGNV YANSIWEELL  360
NPKSACQYDG MPFSMQINTL FANLRRVIIS NCQHEYGKVS ASMTLRGCID ILLLLKRISM  420
AFTDEYYHVS LQRNYLQTRK ELVIVSNCCL VKGVVGTLYF IWLVKVRTLA W*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3jue_A	7e-21	280	357	39	114	ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3jue_B	7e-21	280	357	39	114	ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3t9k_A	7e-21	280	357	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
3t9k_B	7e-21	280	357	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1
4f1p_A	6e-21	280	357	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p_B	6e-21	280	357	39	114	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in the spatial control of provascular differentiation. Required for the formation of the normal pattern of continuous secondary veins. Involved in auxin signaling but not in polar auxin transport or in auxin responses. Required for PIN1 internalization in roots. {ECO:0000269\|PubMed:10887076, ECO:0000269\|PubMed:10887077, ECO:0000269\|PubMed:15743878, ECO:0000269\|PubMed:16698946}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by auxin. {ECO:0000269\|PubMed:15743878}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012856613.1	1e-155	PREDICTED: ADP-ribosylation factor GTPase-activating protein AGD3 isoform X1
Refseq	XP_012856614.1	1e-156	PREDICTED: ADP-ribosylation factor GTPase-activating protein AGD3 isoform X2
Swissprot	Q5W7F2	1e-146	AGD3_ARATH; ADP-ribosylation factor GTPase-activating protein AGD3
TrEMBL	A0A022Q5K2	1e-154	A0A022Q5K2_ERYGU; Uncharacterized protein
TrEMBL	A0A2G9GHX6	1e-155	A0A2G9GHX6_9LAMI; Myotrophin
STRING	Migut.I00616.1.p	1e-155	(Erythranthe guttata)

Link Out ? help Back to Top
Phytozome	Kalax.1691s0002.2.p

Publications ? help Back to Top
Koizumi K,Sugiyama M,Fukuda H A series of novel mutants of Arabidopsis thaliana that are defective in the formation of continuous vascular network: calling the auxin signal flow canalization hypothesis into question. Development, 2000. 127(15): p. 3197-204 [PMID:10887076] Vernoud V,Horton AC,Yang Z,Nielsen E Analysis of the small GTPase gene superfamily of Arabidopsis. Plant Physiol., 2003. 131(3): p. 1191-208 [PMID:12644670] Sawa S,Demura T,Horiguchi G,Kubo M,Fukuda H The ATE genes are responsible for repression of transdifferentiation into xylem cells in Arabidopsis. Plant Physiol., 2005. 137(1): p. 141-8 [PMID:15618413] Sawa S, et al. DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis. Plant Physiol., 2005. 138(2): p. 819-26 [PMID:15923323] Sieburth LE, et al. SCARFACE encodes an ARF-GAP that is required for normal auxin efflux and vein patterning in Arabidopsis. Plant Cell, 2006. 18(6): p. 1396-411 [PMID:16698946] Naramoto S, et al. Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants. Development, 2009. 136(9): p. 1529-38 [PMID:19363154] Carland F,Nelson T CVP2- and CVL1-mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns. Plant J., 2009. 59(6): p. 895-907 [PMID:19473324] Naramoto S, et al. ADP-ribosylation factor machinery mediates endocytosis in plant cells. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(50): p. 21890-5 [PMID:21118984] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Prabhakaran Mariyamma N,Hou H,Carland FM,Nelson T,Schultz EA Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion. J. Exp. Bot., 2017. 68(13): p. 3375-3390 [PMID:28575401]