PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa000820

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NAC

Protein Properties

Length: 601aa MW: 67907 Da PI: 4.382

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-28707	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	172.7	1.1e-53	18	145	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 l+pGfrFhPtdeelv +yL++k+ gk++++ ++i++vd+ykvePwdLp +++k+++ ewyfFs dkky +g+r+nrat++gyWk+tgkd++v++ +++ Lsa000820 18 LAPGFRFHPTDEELVRYYLRRKICGKPFRF-DAISDVDVYKVEPWDLPglSRLKSRDLEWYFFSVLDKKYGNGSRTNRATDKGYWKTTGKDRSVYH-RSQ 115 579************************9.99***********6448888999**********************************.999 PP NAM 99 lvglkktLvfykgrapkgektdWvmheyrl 128 lvg+kktLv++ grapkge+t+Wvmheyrl Lsa000820 116 LVGMKKTLVYHIGRAPKGERTNWVMHEYRL 145 **************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	4.32E-64	11	168	IPR003441	NAC domain
PROSITE profile	PS51005	58.919	18	168	IPR003441	NAC domain
Pfam	PF02365	2.5E-27	20	145	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 601 aa Download sequence Send to blast
MAVVLDSVTP APTTASSLAP GFRFHPTDEE LVRYYLRRKI CGKPFRFDAI SDVDVYKVEP 60 WDLPGLSRLK SRDLEWYFFS VLDKKYGNGS RTNRATDKGY WKTTGKDRSV YHRSQLVGMK 120 KTLVYHIGRA PKGERTNWVM HEYRLIDQEL EKAGIIQDSF VLCRIFRKSG SGPKNGEQYG 180 APFVEEEWED DELVMVPKQE FAEDFPVDDD DAYLDANDLE QILGSDTPDK VAPLPLDLHD 240 GDNLSSADVS TEMIEDHPQK LLMDEGENQH QAEKEDGPKL FDLPVQNEMD PKSVKHEYIG 300 ETNNASDFDV DYLLDEPFFD ASTGDFQFDA SSFLEADDLK NEVKTEPGLE MFDEYTSFIN 360 PTNNLEYTFD SIDNEDILPE SSLILENANE DTHDAIEATQ QFFEGQNCNI APAKVEQPDL 420 ATGNNVASSS GQEHQDSAPH EANEASQQPF EEFAYPLSPE GELHAGEHIC TTSICIRVSF 480 KVFGSCCFTS FNISSGDHWN DPYKRRFFHR DQTGLVIGEE WSSGHCSLIE VGSRSKSKSK 540 CCWKGAFRCF QELVFLPVSV HHGCFVELPD QQSHLSKVIH ELKKENGQWS TTGGGYASAS 600 W

Sequence ? help Back to Top

Protein Sequence Length: 601 aa Download sequence Send to blast

MAVVLDSVTP APTTASSLAP GFRFHPTDEE LVRYYLRRKI CGKPFRFDAI SDVDVYKVEP  60
WDLPGLSRLK SRDLEWYFFS VLDKKYGNGS RTNRATDKGY WKTTGKDRSV YHRSQLVGMK  120
KTLVYHIGRA PKGERTNWVM HEYRLIDQEL EKAGIIQDSF VLCRIFRKSG SGPKNGEQYG  180
APFVEEEWED DELVMVPKQE FAEDFPVDDD DAYLDANDLE QILGSDTPDK VAPLPLDLHD  240
GDNLSSADVS TEMIEDHPQK LLMDEGENQH QAEKEDGPKL FDLPVQNEMD PKSVKHEYIG  300
ETNNASDFDV DYLLDEPFFD ASTGDFQFDA SSFLEADDLK NEVKTEPGLE MFDEYTSFIN  360
PTNNLEYTFD SIDNEDILPE SSLILENANE DTHDAIEATQ QFFEGQNCNI APAKVEQPDL  420
ATGNNVASSS GQEHQDSAPH EANEASQQPF EEFAYPLSPE GELHAGEHIC TTSICIRVSF  480
KVFGSCCFTS FNISSGDHWN DPYKRRFFHR DQTGLVIGEE WSSGHCSLIE VGSRSKSKSK  540
CCWKGAFRCF QELVFLPVSV HHGCFVELPD QQSHLSKVIH ELKKENGQWS TTGGGYASAS  600
W

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	5e-50	12	174	11	171	NO APICAL MERISTEM PROTEIN
1ut4_B	5e-50	12	174	11	171	NO APICAL MERISTEM PROTEIN
1ut7_A	5e-50	12	174	11	171	NO APICAL MERISTEM PROTEIN
1ut7_B	5e-50	12	174	11	171	NO APICAL MERISTEM PROTEIN
3swm_A	5e-50	12	174	14	174	NAC domain-containing protein 19
3swm_B	5e-50	12	174	14	174	NAC domain-containing protein 19
3swm_C	5e-50	12	174	14	174	NAC domain-containing protein 19
3swm_D	5e-50	12	174	14	174	NAC domain-containing protein 19
3swp_A	5e-50	12	174	14	174	NAC domain-containing protein 19
3swp_B	5e-50	12	174	14	174	NAC domain-containing protein 19
3swp_C	5e-50	12	174	14	174	NAC domain-containing protein 19
3swp_D	5e-50	12	174	14	174	NAC domain-containing protein 19
4dul_A	5e-50	12	174	11	171	NAC domain-containing protein 19
4dul_B	5e-50	12	174	11	171	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). Transcripition activator associated with the induction of genes related to flavonoid biosynthesis and required for the accumulation of anthocyanins in response to high light stress (PubMed:19887540). Plays a role in the regulation of 20S and 26S proteasomes in response to high light stress (PubMed:21889048). {ECO:0000250\|UniProtKB:Q949N0, ECO:0000269\|PubMed:19887540, ECO:0000269\|PubMed:21889048}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By exposure to high light (PubMed:19887540). Induced by heat and methyl methanesulfonate (MMS) treatment (PubMed:17158162). {ECO:0000269\|PubMed:17158162, ECO:0000269\|PubMed:19887540}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023751379.1	0.0	NAC domain-containing protein 53-like
Swissprot	Q84K00	1e-102	NAC78_ARATH; NAC domain-containing protein 78
TrEMBL	A0A2J6M5G6	0.0	A0A2J6M5G6_LACSA; Uncharacterized protein
STRING	PGSC0003DMT400079789	1e-143	(Solanum tuberosum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04410.1	1e-105	NAC domain containing protein 2

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Liang M, et al. Subcellular Distribution of NTL Transcription Factors in Arabidopsis thaliana. Traffic, 2015. 16(10): p. 1062-74 [PMID:26201836] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Gladman NP,Marshall RS,Lee KH,Vierstra RD The Proteasome Stress Regulon Is Controlled by a Pair of NAC Transcription Factors in Arabidopsis. Plant Cell, 2016. 28(6): p. 1279-96 [PMID:27194708] Tang Y,Zhao CY,Tan ST,Xue HW Arabidopsis Type II Phosphatidylinositol 4-Kinase PI4Kγ5 Regulates Auxin Biosynthesis and Leaf Margin Development through Interacting with Membrane-Bound Transcription Factor ANAC078. PLoS Genet., 2016. 12(8): p. e1006252 [PMID:27529511]