PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa001015
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family TALE
Protein Properties Length: 178aa    MW: 21039.4 Da    PI: 8.4426
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58671565PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox29.81e-091211552155
                HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
   Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                + +yp+++++  LA+++gL+++q+ +WF N+R ++
  Lsa001015 121 RWPYPTEADKIALAESTGLDQKQINNWFINQRKRH 155
                569*****************************985 PP
2ELK331.4e-117696222
        ELK  2 LKhqLlrKYsgyLgsLkqEFs 22
               LK+ LlrKYs y++sLk+EFs
  Lsa001015 76 LKEKLLRKYSKYISSLKHEFS 96
               9*******************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF037911.2E-14237IPR005541KNOX2
SMARTSM012569.9E-8238IPR005541KNOX2
PROSITE profilePS512139.4817595IPR005539ELK domain
SMARTSM011885.7E-67596IPR005539ELK domain
PfamPF037892.9E-77696IPR005539ELK domain
PROSITE profilePS5007112.61795158IPR001356Homeobox domain
SuperFamilySSF466891.28E-2097170IPR009057Homeodomain-like
SMARTSM003891.1E-1397162IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.609.2E-29100159IPR009057Homeodomain-like
CDDcd000861.49E-11107159No hitNo description
PfamPF059201.8E-17115154IPR008422Homeobox KN domain
PROSITE patternPS000270133156IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 178 aa     Download sequence    Send to blast
XETYCEMLDK YRSDLARPFD EATTFLNNMQ TQLTNLCKGT SITYHTDESV EKSEEDLSRG  60
ESEVPKSNWT NEDRALKEKL LRKYSKYISS LKHEFSNKKK KGKLPKEARQ VLLDWWNVHY  120
RWPYPTEADK IALAESTGLD QKQINNWFIN QRKRHWKPSE NMQFAVMDSL CGSFLVNN
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023752330.11e-130homeobox protein knotted-1-like 6
SwissprotQ84JS64e-75KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A2J6M3J31e-128A0A2J6M3J3_LACSA; Uncharacterized protein
STRINGVIT_17s0000g08710.t011e-86(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.12e-77KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]