PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa001938
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family bHLH
Protein Properties Length: 332aa    MW: 37001.3 Da    PI: 7.9145
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S32122678PU_unrefUnigeneView CDS
PUT-187a-Lactuca_sativa-26171PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH34.14.8e-11167214454
                HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
        HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                ++  rE+rRRd++N++f+eL e+l +    + +K +K  iL  A++ +++L
  Lsa001938 167 TKACREKRRRDKLNERFQELNEILDPG---RPPKTDKTVILGDAIRRVNQL 214
                5678**********************8...88*************999988 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088813.421163214IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.7E-8167214IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000835.14E-8167217No hitNo description
SuperFamilySSF474599.95E-13168239IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.3E-12168236IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.4E-8169220IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 332 aa     Download sequence    Send to blast
IKYYIGDVQC FDAPTPAIGP ILILLSPKIN FALLSIPVSI SPISSLDAFK HKAYINFIRV  60
IDISAQFRRG FKIPARINRF CSEEIMVAPE DDDNSNCFFD FSLIEQIPVP GGELPPLESD  120
FHWSSNPFPG PSNLSAGFLD SSGKPNYSNE LGSRKRANPG LCSSTDTKAC REKRRRDKLN  180
ERFQELNEIL DPGRPPKTDK TVILGDAIRR VNQLRDEALK LKESAQELQS KINELKAEKN  240
ELRDEKQKLK AEKERLEQQV KAFGRSPAPA AATAAFFPPP PHAAMPIPFP ANHMVDGKFM  300
PIMGYHGVPM WPFAPTAAVD TSEDHVHRSP LA
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1153175RKRANPGLCSSTDTKACREKRRR
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022016699.11e-122transcription factor bHLH115-like isoform X2
RefseqXP_022016700.11e-122transcription factor bHLH115-like isoform X3
SwissprotQ9FH371e-63ILR3_ARATH; Transcription factor ILR3
TrEMBLA0A2J6JHQ41e-123A0A2J6JHQ4_LACSA; Uncharacterized protein
STRINGXP_009366840.13e-82(Pyrus x bretschneideri)
STRINGEMJ131363e-82(Prunus persica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.12e-58bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]