PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa002292

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

C2H2

Protein Properties

Length: 464aa MW: 51581.8 Da PI: 6.0119

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58690537	PU_ref	Unigene	View CDS
PUT-187a-Lactuca_sativa-44234	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.2	0.0011	116	138	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp Cg+ F + ++ H ++ Lsa002292 116 FECPVCGRAFGSEEEVSDHVESC 138 89**********99999998766 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	9.12	116	145	IPR007087	Zinc finger, C2H2
CDD	cd09212	1.28E-20	167	238	No hit	No description
SuperFamily	SSF143503	2.62E-19	174	257	IPR018997	PUB domain
SMART	SM00580	2.0E-15	178	245	IPR018997	PUB domain
Pfam	PF09409	6.1E-17	179	253	IPR018997	PUB domain
SuperFamily	SSF54236	3.1E-13	320	430	IPR029071	Ubiquitin-related domain
SMART	SM00166	0.0029	345	432	IPR001012	UBX domain
Gene3D	G3DSA:3.10.20.90	1.6E-9	349	432	No hit	No description
PROSITE profile	PS50033	12.29	349	430	IPR001012	UBX domain
Pfam	PF00789	1.5E-7	350	405	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005515	Molecular Function	protein binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 464 aa Download sequence Send to blast
MGDMKDKMKG FMKKFNNSLS SSSSPGKFKG QGRVLGSSSS SNPSGQVNSN PNRPTTTIQD 60 PKPIPPPRPS PSTSNISPKT PAISEQPTKS TDGFDPFDSL ITTGKRNKNG YDLKVFECPV 120 CGRAFGSEEE VSDHVESCLS KNEAESQSTT DNPQEKDETR SELEVCVSTY LSGKPSDASV 180 EIVLKLLKNI VREPENVKFR RIRLGNPKIK EAIADVPGGL DLLECVGFEL KEESEEMWAT 240 MEAASNEKIK LIKQTVYLLE PQKIETLTST AAQTKVVEPE EVKTVERQIR VFFSVSESVA 300 AKIELPDSFY KLSIEEVRKE AELRRKKLAE SQLLVPKSFK EKQAKAARKR HQKTLIRIQF 360 PDGVVLQAFF NPKEPTSSLY EFVSSSLKDP SLEFELLHPV LIKRRVIPNI GEKVITLEEE 420 DLVPSALIKF RPKETDSVVF TGLCNELLEI MEPLVSESAV ASSQ

Sequence ? help Back to Top

Protein Sequence Length: 464 aa Download sequence Send to blast

MGDMKDKMKG FMKKFNNSLS SSSSPGKFKG QGRVLGSSSS SNPSGQVNSN PNRPTTTIQD  60
PKPIPPPRPS PSTSNISPKT PAISEQPTKS TDGFDPFDSL ITTGKRNKNG YDLKVFECPV  120
CGRAFGSEEE VSDHVESCLS KNEAESQSTT DNPQEKDETR SELEVCVSTY LSGKPSDASV  180
EIVLKLLKNI VREPENVKFR RIRLGNPKIK EAIADVPGGL DLLECVGFEL KEESEEMWAT  240
MEAASNEKIK LIKQTVYLLE PQKIETLTST AAQTKVVEPE EVKTVERQIR VFFSVSESVA  300
AKIELPDSFY KLSIEEVRKE AELRRKKLAE SQLLVPKSFK EKQAKAARKR HQKTLIRIQF  360
PDGVVLQAFF NPKEPTSSLY EFVSSSLKDP SLEFELLHPV LIKRRVIPNI GEKVITLEEE  420
DLVPSALIKF RPKETDSVVF TGLCNELLEI MEPLVSESAV ASSQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifs_A	4e-16	300	463	19	168	Tether containing UBX domain for GLUT4
5ifs_C	4e-16	300	463	19	168	Tether containing UBX domain for GLUT4
5ifw_A	2e-16	300	463	19	168	Tether containing UBX domain for GLUT4
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Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023738710.1	0.0	plant UBX domain-containing protein 2
Swissprot	Q9ZU93	1e-175	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A2J6K4K7	0.0	A0A2J6K4K7_LACSA; Uncharacterized protein
STRING	XP_009793042.1	0.0	(Nicotiana sylvestris)

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]