PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa002459

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

bHLH

Protein Properties

Length: 216aa MW: 24499.7 Da PI: 5.7184

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58679544	PU_ref	Unigene	View CDS
PUT-187a-Lactuca_sativa-30527	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	30	9.6e-10	69	117	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +++ rEr+RR+++N++f eL + l + + ++K +iL A++ +++L Lsa002459 69 ENKACRERQRREKLNDRFLELSSTLEPG---RPVTNDKLAILGDAIRVLNQL 117 56789********************7...7899************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.44E-12	59	131	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	8.36E-7	64	122	No hit	No description
PROSITE profile	PS50888	12.709	66	117	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.2E-10	69	139	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.4E-7	69	117	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.6E-8	72	123	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 216 aa Download sequence Send to blast
MDSFESTNWD LIDYSSLIND VASTDLYWGD QSAAIPVDAP LASLAPLDEC AEKECTRKRG 60 RSNSCSRAEN KACRERQRRE KLNDRFLELS STLEPGRPVT NDKLAILGDA IRVLNQLKSE 120 SQECKEMNEK LLEEIKTLKA EKNELREEKL VLKAEKAKME QQVKALTNHT PHGFMTPHPA 180 SKMPVFPGYG YIPMWQYLPQ SAQDTSHDHE LRPPAA

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023743446.1	1e-161	transcription factor bHLH104-like
Swissprot	Q8L467	9e-67	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A2J6JUF7	1e-160	A0A2J6JUF7_LACSA; Uncharacterized protein
STRING	Solyc09g089870.2.1	4e-96	(Solanum lycopersicum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.1	4e-58	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]