PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa004040

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

HSF

Protein Properties

Length: 281aa MW: 31646.3 Da PI: 5.0072

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-16741	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	111.4	6.3e-35	10	101	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+y++++d+ ++e+isw+e+gn fvv+++ +fa+++Lp+ Fkh+nf+SFvRQLn+YgF+k+ ++ weF++++Fk+g+k+ll +i+ Lsa004040 10 FLMKTYQLVDDPITDEMISWNETGNGFVVWKTADFARDLLPNSFKHNNFSSFVRQLNTYGFHKTLPDK---------WEFANEYFKRGRKDLLIEIH 97 9*************************************************************9999.........**************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k+ Lsa004040 98 RRKT 101 86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.3E-36	3	94	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.77E-31	6	99	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.0E-54	6	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	7.6E-30	10	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.2E-18	10	33	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.2E-18	48	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.2E-18	61	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 281 aa Download sequence Send to blast
MVHRSAPAPF LMKTYQLVDD PITDEMISWN ETGNGFVVWK TADFARDLLP NSFKHNNFSS 60 FVRQLNTYGF HKTLPDKWEF ANEYFKRGRK DLLIEIHRRK TVTPTKGKSD GDGGLASPPS 120 SSGDDLRSSS TSSPNSKNPG SVVLPTVEKL ENLSDENEKL KKEKQFLTSE LAQAKKQCDD 180 LVAFLTQSVK VAPEQVSRIM SGDVVVGETE TVVQETDGDD DDKDGDCFRL FGVLLRDGKK 240 KRGREEINET SGVEMKNMKL QGDFNDDNPW MNSLYSVTEQ Y

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	7e-21	5	101	25	131	Heat shock factor protein 1
5d5v_B	7e-21	5	101	25	131	Heat shock factor protein 1
5d5v_D	7e-21	5	101	25	131	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023737719.1	0.0	heat shock factor protein HSF24-like
Swissprot	P22335	1e-99	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A2J6K6R9	0.0	A0A2J6K6R9_LACSA; Uncharacterized protein
STRING	VIT_07s0031g00670.t01	1e-102	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	1e-68	heat shock factor 4

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]