PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa004968

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

C2H2

Protein Properties

Length: 373aa MW: 42192.7 Da PI: 7.0435

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58684992	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.1	3.3e-05	212	231	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ Lsa004968 212 FSCPVCFKTFNRYNNMQMHM 231 89*****************9 PP
2	zf-C2H2	15.4	5.3e-05	296	318	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C +Cgk+F + + ++H +++ Lsa004968 296 FMCRKCGKTFAVRGDWRTHEKNC 318 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00355	0.38	212	234	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.64	212	239	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	5.4E-6	212	231	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	214	234	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50868	8.086	254	270	IPR003616	Post-SET domain
SuperFamily	SSF57667	2.5E-6	277	316	No hit	No description
Gene3D	G3DSA:3.30.160.60	2.3E-5	292	316	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	35	296	316	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.725	296	316	IPR007087	Zinc finger, C2H2
SMART	SM00355	150	322	345	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 373 aa Download sequence Send to blast
MTDPYSSNLY SQYFRFDQFC NNSATNLPHH IQYNLHEQHP QSYHYSSVQS SSYSNTRITN 60 SFYFNPSTSV PNQHPTPPPS PPLREALPLL SWSPSRKHED YHQPSCSSTT QQDMDVEAVD 120 GGDEEDDETA VTVALHIGLP NASAADLASL ISNSSNSSST TSEIRVPYSI NDTTKEGDGN 180 EGNLGYNPIS RLNKGQYWIP TPSQILIGPT QFSCPVCFKT FNRYNNMQMH MWGHGSQYRK 240 GPESLRGTQP TGMLKLPCYC CAPGCRNHID HPRSKPLKDF RTLQTHYKRK HGIKPFMCRK 300 CGKTFAVRGD WRTHEKNCGK LWYCICGSDF KHKRSLKDHI KAFGHGHAAY GINGFEEDDE 360 PASEIEQDDD ENL

Sequence ? help Back to Top

Protein Sequence Length: 373 aa Download sequence Send to blast

MTDPYSSNLY SQYFRFDQFC NNSATNLPHH IQYNLHEQHP QSYHYSSVQS SSYSNTRITN  60
SFYFNPSTSV PNQHPTPPPS PPLREALPLL SWSPSRKHED YHQPSCSSTT QQDMDVEAVD  120
GGDEEDDETA VTVALHIGLP NASAADLASL ISNSSNSSST TSEIRVPYSI NDTTKEGDGN  180
EGNLGYNPIS RLNKGQYWIP TPSQILIGPT QFSCPVCFKT FNRYNNMQMH MWGHGSQYRK  240
GPESLRGTQP TGMLKLPCYC CAPGCRNHID HPRSKPLKDF RTLQTHYKRK HGIKPFMCRK  300
CGKTFAVRGD WRTHEKNCGK LWYCICGSDF KHKRSLKDHI KAFGHGHAAY GINGFEEDDE  360
PASEIEQDDD ENL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023730973.1	0.0	zinc finger protein WIP2-like
Swissprot	Q9SVY1	1e-139	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	A0A2J6KM93	0.0	A0A2J6KM93_LACSA; Uncharacterized protein
STRING	cassava4.1_010785m	1e-162	(Manihot esculenta)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-130	C2H2 family protein

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]