PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa006451
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family MIKC_MADS
Protein Properties Length: 261aa    MW: 30467.6 Da    PI: 9.6265
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58679675PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-15112PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF97.17.3e-314493150
               S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE CS
     SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeys 50
               krien++nrqvtf+kRrng+lKKA+ELSvLCdae+a+i+fs++g+lyey+
  Lsa006451 44 KRIENNTNRQVTFCKRRNGLLKKAYELSVLCDAEIALIVFSTRGRLYEYA 93
               79***********************************************8 PP
2K-box98.87.7e-331142088100
      K-box   8 s..leeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100
                   l+e++a+ +qqe++kL+++i++ q ++Rhl+Ge+L+ L++keL+qLe++Le++++kiRskK++++l+++e lqk+e el+++n+ Lr+k++e
  Lsa006451 114 TfsLQETNAQFYQQEAKKLRQQIQMRQDSNRHLMGEGLDCLNMKELKQLETRLERGISKIRSKKHDMILAEMEFLQKREVELEHHNTFLRSKIAE 208
                14599***************************************************************************************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006633.8943696IPR002100Transcription factor, MADS-box
SMARTSM004323.1E-413695IPR002100Transcription factor, MADS-box
CDDcd002654.77E-4337110No hitNo description
SuperFamilySSF554559.42E-3337112IPR002100Transcription factor, MADS-box
PROSITE patternPS0035003892IPR002100Transcription factor, MADS-box
PRINTSPR004041.3E-323858IPR002100Transcription factor, MADS-box
PfamPF003194.7E-264592IPR002100Transcription factor, MADS-box
PRINTSPR004041.3E-325873IPR002100Transcription factor, MADS-box
PRINTSPR004041.3E-327394IPR002100Transcription factor, MADS-box
PfamPF014865.1E-24118206IPR002487Transcription factor, K-box
PROSITE profilePS5129714.616122212IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 261 aa     Download sequence    Send to blast
XEAWFVGFLR LPSIEERLKR GDFLERGVLS SSKENMGRGK IEIKRIENNT NRQVTFCKRR  60
NGLLKKAYEL SVLCDAEIAL IVFSTRGRLY EYANNNMRST IEKYKKATSN TPNTFSLQET  120
NAQFYQQEAK KLRQQIQMRQ DSNRHLMGEG LDCLNMKELK QLETRLERGI SKIRSKKHDM  180
ILAEMEFLQK REVELEHHNT FLRSKIAENE RVQQHEVDGA EQYNAIQAYL ARNSLQLNIM  240
EPLEDAPSAY PLLPNKSLHI G
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tqe_P3e-2236104169Myocyte-specific enhancer factor 2B
1tqe_Q3e-2236104169Myocyte-specific enhancer factor 2B
1tqe_R3e-2236104169Myocyte-specific enhancer factor 2B
1tqe_S3e-2236104169Myocyte-specific enhancer factor 2B
6c9l_A3e-2236104169Myocyte-specific enhancer factor 2B
6c9l_B3e-2236104169Myocyte-specific enhancer factor 2B
6c9l_C3e-2236104169Myocyte-specific enhancer factor 2B
6c9l_D3e-2236104169Myocyte-specific enhancer factor 2B
6c9l_E3e-2236104169Myocyte-specific enhancer factor 2B
6c9l_F3e-2236104169Myocyte-specific enhancer factor 2B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in seed development (PubMed:21447172, Ref.1, PubMed:29853599). Plays a role in seed morphogenesis by promoting the correct development of endotesta cell layer, which directs the further development of the seed coat, the endosperm, and consequently the embryo (Ref.1, PubMed:29853599). {ECO:0000269|PubMed:21447172, ECO:0000269|PubMed:29853599, ECO:0000269|Ref.1}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023760420.11e-167agamous-like MADS-box protein AGL11
SwissprotF6I4571e-106AG11C_VITVI; Agamous-like MADS-box protein AGL11
TrEMBLA0A2J6LL661e-166A0A2J6LL66_LACSA; Uncharacterized protein
STRINGSolyc11g028020.1.11e-111(Solanum lycopersicum)
STRINGPGSC0003DMT4000132481e-111(Solanum tuberosum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G09960.12e-99MIKC_MADS family protein
Publications ? help Back to Top
  1. Jaillon O, et al.
    The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla.
    Nature, 2007. 449(7161): p. 463-7
    [PMID:17721507]
  2. Díaz-Riquelme J,Lijavetzky D,Martínez-Zapater JM,Carmona MJ
    Genome-wide analysis of MIKCC-type MADS box genes in grapevine.
    Plant Physiol., 2009. 149(1): p. 354-69
    [PMID:18997115]
  3. Mejía N, et al.
    Molecular, genetic and transcriptional evidence for a role of VvAGL11 in stenospermocarpic seedlessness in grapevine.
    BMC Plant Biol., 2011. 11: p. 57
    [PMID:21447172]
  4. Grimplet J,Martínez-Zapater JM,Carmona MJ
    Structural and functional annotation of the MADS-box transcription factor family in grapevine.
    BMC Genomics, 2016. 17: p. 80
    [PMID:26818751]
  5. Malabarba J, et al.
    The MADS-box gene Agamous-like 11 is essential for seed morphogenesis in grapevine.
    J. Exp. Bot., 2017. 68(7): p. 1493-1506
    [PMID:28369525]
  6. Royo C, et al.
    The Major Origin of Seedless Grapes Is Associated with a Missense Mutation in the MADS-Box Gene VviAGL11.
    Plant Physiol., 2018. 177(3): p. 1234-1253
    [PMID:29853599]