PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa007623

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

MYB

Protein Properties

Length: 287aa MW: 33162.7 Da PI: 6.5068

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-28387	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	56.9	4.9e-18	30	77	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+W+ +Ed++l+ +++q+G ++W++ +++ g+ R++k+c++rw +yl Lsa007623 30 KGPWSHDEDQILISYIQQHGHPNWRALPKHAGLLRCGKSCRLRWTNYL 77 79****************************99**********97 PP
2	Myb_DNA-binding	48.8	1.6e-15	83	128	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+++ eE++ +++++++lG++ W+ Ia ++ gRt++++k+ w++yl Lsa007623 83 RGNFSREEEDTIIHLHEMLGNR-WSVIATNLP-GRTDNEIKNVWHTYL 128 89******************.*****.***********97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	2.7E-25	21	80	IPR009057	Homeodomain-like
PROSITE profile	PS51294	16.771	25	77	IPR017930	Myb domain
SuperFamily	SSF46689	5.24E-29	26	124	IPR009057	Homeodomain-like
SMART	SM00717	5.3E-14	29	79	IPR001005	SANT/Myb domain
Pfam	PF00249	7.3E-16	30	77	IPR001005	SANT/Myb domain
CDD	cd00167	2.37E-10	32	77	No hit	No description
PROSITE profile	PS51294	24.86	78	132	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	7.8E-25	81	132	IPR009057	Homeodomain-like
SMART	SM00717	8.4E-14	82	130	IPR001005	SANT/Myb domain
Pfam	PF00249	1.4E-14	83	128	IPR001005	SANT/Myb domain
CDD	cd00167	3.24E-9	85	128	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 287 aa Download sequence Send to blast
XQGYLHIIST PIVRKRMGRA PCCEKMGLKK GPWSHDEDQI LISYIQQHGH PNWRALPKHA 60 GLLRCGKSCR LRWTNYLRPD IKRGNFSREE EDTIIHLHEM LGNRWSVIAT NLPGRTDNEI 120 KNVWHTYLKK RLESHETTSH APKRHNTKSK RASSNPNLEE SIVSQCHAQP QQNSHDEEQL 180 IYVQPSCSES SSETETTTNS FDVAKHEEIK HETFLDDSFW SETLSGEGDD IMESNPTINI 240 SSVEFSSSPL KVIENEDIRN SYADCHMGSI DLWYDIFTRI EEFTRVT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	8e-27	28	134	5	110	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in cold-regulation of CBF genes and in the development of freezing tolerance. May be part of a complex network of transcription factors controlling the expression of CBF genes and other genes in response to cold stress. Binds to the MYB recognition sequences in the promoters of CBF1, CBF2 and CBF3 genes (PubMed:17015446). Involved in drought and salt tolerance. May enhance expression levels of genes involved in abscisic acid (ABA) biosynthesis and signaling, as well as those encoding stress-protective proteins (PubMed:19161942). {ECO:0000269\|PubMed:17015446, ECO:0000269\|PubMed:19161942}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) and drought stress (PubMed:19161942). Induced by salt stress (PubMed:19161942). {ECO:0000269\|PubMed:19161942}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023735423.1	0.0	transcription factor MYB4-like
Swissprot	Q9LTC4	1e-80	MYB15_ARATH; Transcription factor MYB15
TrEMBL	A0A2J6KBW1	0.0	A0A2J6KBW1_LACSA; Uncharacterized protein
STRING	POPTR_0005s24550.1	9e-84	(Populus trichocarpa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23250.1	8e-80	myb domain protein 15

Publications ? help Back to Top
Schnaubelt D, et al. Low glutathione regulates gene expression and the redox potentials of the nucleus and cytosol in Arabidopsis thaliana. Plant Cell Environ., 2015. 38(2): p. 266-79 [PMID:24329757] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ma X, et al. CYCLIN-DEPENDENT KINASE G2 regulates salinity stress response and salt mediated flowering in Arabidopsis thaliana. Plant Mol. Biol., 2015. 88(3): p. 287-99 [PMID:25948280] Kim SH, et al. Phosphorylation of the transcriptional repressor MYB15 by mitogen-activated protein kinase 6 is required for freezing tolerance in Arabidopsis. Nucleic Acids Res., 2017. 45(11): p. 6613-6627 [PMID:28510716] Chezem WR,Memon A,Li FS,Weng JK,Clay NK SG2-Type R2R3-MYB Transcription Factor MYB15 Controls Defense-Induced Lignification and Basal Immunity in Arabidopsis. Plant Cell, 2017. 29(8): p. 1907-1926 [PMID:28733420] Pal S, et al. TransDetect Identifies a New Regulatory Module Controlling Phosphate Accumulation. Plant Physiol., 2017. 175(2): p. 916-926 [PMID:28827455]