PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa007907
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family E2F/DP
Protein Properties Length: 357aa    MW: 38781.3 Da    PI: 6.8939
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58688381PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.42.1e-27106187371
    E2F_TDP   3 eksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                +++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wkg
  Lsa007907 106 GRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfadpgdggqtpdqqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWKG 187
                689*******...*****999*******************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.6E-46100191IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-34104187IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.72E-21107188IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023194.0E-25107187IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd144581.33E-43192295IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440741.05E-41193305No hitNo description
SMARTSM011385.3E-64194355IPR014889Transcription factor DP, C-terminal
PfamPF087817.2E-41195305IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 357 aa     Download sequence    Send to blast
MVTAGSNNQD EVIGDKHPSS AVSRGGGGAT RSWGTTASGQ SVSTSGSVGS PSTRSEATMA  60
VTPASENTFL RLNHLDIQTD NAGSQAAAGN KKKKRAQRAT GGDKGGRGLR QFSMKVCEKV  120
ESKGRTTYNE VADELVAEFA DPGDGGQTPD QQQYDEKNIR RRVYDALNVL MAMDIISKDK  180
KEIQWKGLPR STLNDIEEIK GERLAIRNRI EKKTAYLKEL QDQYVGLQNL IQRNEELYTS  240
GNAPSGGVAL PFILVQTRPH ATVEVEISED MQLVHFDFNS TPFELHDDNY VLKAMKLSDQ  300
SKHDDVANNV CVDVDGGEGS SISSMFRPSL GPTMPPGRGS KLPSVPGILK GRVKHEF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B1e-3798189190PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023744869.10.0transcription factor-like protein DPB isoform X1
SwissprotQ9FNY21e-161DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A2J6JRH40.0A0A2J6JRH4_LACSA; Uncharacterized protein
STRINGXP_010241817.10.0(Nelumbo nucifera)