PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa008378
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family HD-ZIP
Protein Properties Length: 835aa    MW: 92167.7 Da    PI: 6.6415
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-187a-Lactuca_sativa-29389PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.36.4e-191775357
               --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
   Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
               k  ++t+eq+e+Le+l++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Lsa008378 17 KYVRYTPEQVEALERLYHECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 75
               5679*****************************************************97 PP
2START159.91.9e-501613692205
                HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEXXT CS
      START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvaelq 99 
                +aee+++e+++ka+ ++  Wv+++ +++g++++ +++ s++++g a+ra+g+v  ++ ++ve+l d++  W +++++++tl+v+ ++  g+++l +++l+
  Lsa008378 161 IAEETLTEFLSKATGTAIEWVQMPGMKPGPDSIGIVAISHGCTGVAARACGLVALEPSRVVEILKDRP-SWYRDCRAVDTLNVLPTAngGTIELLYMQLY 259
                789*******************************************************9998888888.****************9999*********** PP

                TXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHH CS
      START 100 alsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegakt 195
                a+++l+   df+ +Ry+   ++g++vi+++S++++q+ p+    +++vRae+l Sg+li+p+++g+s +++v+h++l++++++++lr+l++s+++ ++kt
  Lsa008378 260 APTTLATaLDFLLLRYTSVTEDGSLVICERSLNNTQNGPSipsVPNFVRAEMLASGYLIRPCEGGGSIIHIVDHMNLEAWSVPEVLRPLYESSTVLAQKT 359
                ***************************************999899******************************************************* PP

                HHHHTXXXXX CS
      START 196 wvatlqrqce 205
                ++ +l+++++
  Lsa008378 360 TMMALRQLRQ 369
                *****99876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.6291276IPR001356Homeobox domain
SMARTSM003891.3E-151480IPR001356Homeobox domain
SuperFamilySSF466894.71E-171679IPR009057Homeodomain-like
CDDcd000861.28E-161777No hitNo description
PfamPF000461.6E-161875IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.601.0E-181975IPR009057Homeodomain-like
CDDcd146864.56E-669108No hitNo description
PROSITE profilePS5084824.309151366IPR002913START domain
CDDcd088751.13E-73155370No hitNo description
Gene3DG3DSA:3.30.530.204.5E-20157366IPR023393START-like domain
SuperFamilySSF559612.61E-33160349No hitNo description
SMARTSM002341.2E-33160370IPR002913START domain
PfamPF018529.2E-48161369IPR002913START domain
PfamPF086708.2E-49693834IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 835 aa     Download sequence    Send to blast
MSMSCKDGNG AMMDNGKYVR YTPEQVEALE RLYHECPKPS SLRRQQLIRE CPILSNIEPK  60
QIKVWFQNRR CREKQRKEAS RLQTVNRKLS AMNKLLMEEN DRLQKQVSHL VYENGCFRQH  120
TQNTTLATKD TSCESVVTNG QHRLTPKHPP RDASPARLLS IAEETLTEFL SKATGTAIEW  180
VQMPGMKPGP DSIGIVAISH GCTGVAARAC GLVALEPSRV VEILKDRPSW YRDCRAVDTL  240
NVLPTANGGT IELLYMQLYA PTTLATALDF LLLRYTSVTE DGSLVICERS LNNTQNGPSI  300
PSVPNFVRAE MLASGYLIRP CEGGGSIIHI VDHMNLEAWS VPEVLRPLYE SSTVLAQKTT  360
MMALRQLRQI SLEVSQSGAS NWGRRPAALR ALSQRLSRGF NEALNGFTDE GWSLIANDGV  420
DDVTIQVNSS PEKLMGLNLP FANRYPPVTN SVLCAKASML LQNVPPALLL RFLREHRSEW  480
ADNNFDAYSA ASVKLGPCSF AGSRIGNFGG QVILPLAHTI EHEEVLEVIK MEGIGHCPED  540
ALMPRDMFLL QLCNGMDENA VGMSAELIFA PIDASFADDA PLLPSGFRII PLDPIKDTST  600
PNRTLDLASA LEIRGSGSKI SNDRNIASGN SRSLMTMAFE FAFESHMQEN VAAIARQYVR  660
GIISSVQRVA SALSPNTGPN VGLQFGAPEA HVLARWICRS YSCYLGVELL KCGGEGSEYI  720
LKSLWNHPDA IMCCSLKAMP VFTFANQAGL DMLETTLVAL QDISLEKVLD EHGRKGLFAE  780
FAQIMQQGFA CLQGGVCSSS MGRPVSYERA VAWKVLNEEE NAHCICFRFI NWSFI
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of meristem development to promote lateral organ formation. May regulates procambial and vascular tissue formation or maintenance, and vascular development in inflorescence stems. {ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:15705957, ECO:0000269|PubMed:16617092}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165 and miR166. {ECO:0000269|PubMed:15773855, ECO:0000269|PubMed:16033795, ECO:0000269|PubMed:16617092, ECO:0000269|PubMed:17237362}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023751740.10.0homeobox-leucine zipper protein ATHB-15-like
SwissprotQ9ZU110.0ATB15_ARATH; Homeobox-leucine zipper protein ATHB-15
TrEMBLA0A2J6M4X20.0A0A2J6M4X2_LACSA; Uncharacterized protein
STRINGVIT_09s0002g03740.t010.0(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G52150.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS
    CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules.
    Development, 2016. 143(3): p. 422-6
    [PMID:26700684]