PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa008493
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family WRKY
Protein Properties Length: 353aa    MW: 39806.2 Da    PI: 10.1883
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58686629PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY101.16.7e-32138193359
                -SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   3 DgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                DgynWrKYGqK+vkgsefprsYY+Ct+++C vkkkvers  ++++ e++Y+geHnh+
  Lsa008493 138 DGYNWRKYGQKQVKGSEFPRSYYKCTHPNCVVKKKVERSI-NGEIAETVYKGEHNHT 193
                9***************************************.***************8 PP
2WRKY105.33.2e-33289346259
                --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                 Dg++WrKYGqK+vkg+++prsYYrCt  +C v+k+ver+++dp+v+++tYeg+Hnhe
  Lsa008493 289 ADGFRWRKYGQKVVKGNPYPRSYYRCTGVKCDVRKHVERASDDPNVFITTYEGKHNHE 346
                7********************************************************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.803.8E-28123195IPR003657WRKY domain
SuperFamilySSF1182907.85E-25134195IPR003657WRKY domain
SMARTSM007741.5E-34136194IPR003657WRKY domain
PfamPF031061.8E-24138192IPR003657WRKY domain
PROSITE profilePS5081122.791138195IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.4E-32277348IPR003657WRKY domain
PROSITE profilePS5081133.201283348IPR003657WRKY domain
SuperFamilySSF1182904.32E-28284348IPR003657WRKY domain
SMARTSM007741.1E-37288347IPR003657WRKY domain
PfamPF031062.3E-26290346IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 353 aa     Download sequence    Send to blast
MEVKEAKRTI IAKPVASRPT ISNFGSFSDI LPGAINISPS TEPTVTAIRP KTLRFKPVMS  60
SPNVEILKSD HTSPFLYKPL AKTVSRTTIS LLANMGTCNT SHVQTATQNL ESMNPPKLKS  120
DDKRLQSHTN NSDRPSYDGY NWRKYGQKQV KGSEFPRSYY KCTHPNCVVK KKVERSINGE  180
IAETVYKGEH NHTKPRLPRR HAFDGTIKDS SSQLPSNQLK NDNKLNEVVG SSLRLTNVVK  240
VHEEFDASCM PTLEPITSKR RKITSERYGE GLKEGGVVVH DGIDSEAIAD GFRWRKYGQK  300
VVKGNPYPRS YYRCTGVKCD VRKHVERASD DPNVFITTYE GKHNHEMPMK KLN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A1e-281383491578Probable WRKY transcription factor 4
2lex_A1e-281383491578Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates trichome development, production of mucilage and tannin in seed coats, and maybe root hair development. {ECO:0000269|PubMed:12084832}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not induced by salicylic acid or wounding. {ECO:0000269|PubMed:12084832}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023767873.10.0WRKY transcription factor 44
SwissprotQ9ZUU01e-92WRK44_ARATH; WRKY transcription factor 44
TrEMBLA0A2J6L5I90.0A0A2J6L5I9_LACSA; Uncharacterized protein
STRINGAES817791e-121(Medicago truncatula)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G37260.15e-95WRKY family protein
Publications ? help Back to Top
  1. Kim K,Jiang K,Teng SL,Feldman LJ,Huang H
    Using biologically interrelated experiments to identify pathway genes in Arabidopsis.
    Bioinformatics, 2012. 28(6): p. 815-22
    [PMID:22271267]
  2. Simon M, et al.
    Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes.
    Plant Cell, 2013. 25(9): p. 3175-85
    [PMID:24014549]
  3. Ranocha P,Francoz E,Burlat V,Dunand C
    Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion.
    Plant Signal Behav, 2014. 9(11): p. e977734
    [PMID:25531128]
  4. Verweij W, et al.
    Functionally Similar WRKY Proteins Regulate Vacuolar Acidification in Petunia and Hair Development in Arabidopsis.
    Plant Cell, 2016. 28(3): p. 786-803
    [PMID:26977085]
  5. Gonzalez A, et al.
    TTG2 controls the developmental regulation of seed coat tannins in Arabidopsis by regulating vacuolar transport steps in the proanthocyanidin pathway.
    Dev. Biol., 2016. 419(1): p. 54-63
    [PMID:27046632]
  6. Hassani-Pak K, et al.
    Developing integrated crop knowledge networks to advance candidate gene discovery.
    Appl Transl Genom, 2016. 11: p. 18-26
    [PMID:28018846]