PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa009990

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NAC

Protein Properties

Length: 377aa MW: 42826.5 Da PI: 7.1856

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58681303	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	145.1	3.7e-45	2	120	9	128
NAM 9 PtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLv 107 Ptd+el+++yLkkk++g+++ + ++i+evd +++ePwdLp ++ ++++ew+fFs+r kky++g++++rat+sgyWkatgk+++v+s + ++g+k+tLv Lsa009990 2 PTDDELISYYLKKKLQGSDNCV-DIIPEVDFCRHEPWDLPaISIIQSDNEWFFFSTRGKKYPNGSQSKRATQSGYWKATGKERNVKS-GAVTIGTKRTLV 99 *****************887.99***********557777899**********************************.999***** PP NAM 108 fykgrapkgektdWvmheyrl 128 f+ grapkge+t+W+mhey + Lsa009990 100 FHMGRAPKGERTEWIMHEYCM 120 *****************86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	48.71	1	136	IPR003441	NAC domain
Pfam	PF02365	4.7E-22	2	119	IPR003441	NAC domain
SuperFamily	SSF101941	3.14E-49	2	135	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 377 aa Download sequence Send to blast
XPTDDELISY YLKKKLQGSD NCVDIIPEVD FCRHEPWDLP AISIIQSDNE WFFFSTRGKK 60 YPNGSQSKRA TQSGYWKATG KERNVKSGAV TIGTKRTLVF HMGRAPKGER TEWIMHEYCM 120 NDAAQESLVI CRLRRNSDFR LNESSRGSSD NKSHSGTTNE YANNNQLDGF HDTNDTIKSA 180 SKESTSSYRS HSDDQNDSGS ESNPEANPES PHGSSTPYKD VDDCFADIIN DDIIRLDEST 240 SHSLKFYGFL TKDEPMLIQD PTKCNQKLPP QNIMTSQGTA VRRIKLRRQK GRTHEPPLVD 300 GGLDQHHHPQ TPPLQKKSTG CFISVLSGNA DTLKGSRSTH VILVLLFLVM VFVVWKCDME 360 DWNRQLKHWL RMTADYI

Sequence ? help Back to Top

Protein Sequence Length: 377 aa Download sequence Send to blast

XPTDDELISY YLKKKLQGSD NCVDIIPEVD FCRHEPWDLP AISIIQSDNE WFFFSTRGKK  60
YPNGSQSKRA TQSGYWKATG KERNVKSGAV TIGTKRTLVF HMGRAPKGER TEWIMHEYCM  120
NDAAQESLVI CRLRRNSDFR LNESSRGSSD NKSHSGTTNE YANNNQLDGF HDTNDTIKSA  180
SKESTSSYRS HSDDQNDSGS ESNPEANPES PHGSSTPYKD VDDCFADIIN DDIIRLDEST  240
SHSLKFYGFL TKDEPMLIQD PTKCNQKLPP QNIMTSQGTA VRRIKLRRQK GRTHEPPLVD  300
GGLDQHHHPQ TPPLQKKSTG CFISVLSGNA DTLKGSRSTH VILVLLFLVM VFVVWKCDME  360
DWNRQLKHWL RMTADYI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	1e-35	2	120	23	140	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP), probably via metalloprotease activity. Regulates gibberellic acid-mediated salt-responsive repression of seed germination and flowering via FT, thus delaying seed germination under high salinity conditions. {ECO:0000269\|PubMed:17410378, ECO:0000269\|PubMed:18363782, ECO:0000269\|PubMed:19704528, ECO:0000269\|PubMed:19704545}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By high salt stress (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Repressed by gibberellic acid (GA), but induced by the GA biosynthetic inhibitor paclabutrazol (PAC) (PubMed:18363782). Accumulates transiently in seeds upon imbibition (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Induced by drought stress (PubMed:17158162). {ECO:0000269\|PubMed:17158162, ECO:0000269\|PubMed:17410378, ECO:0000269\|PubMed:18363782, ECO:0000269\|PubMed:19704528, ECO:0000269\|PubMed:19704545}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023736136.1	0.0	NAC domain-containing protein 40-like
Swissprot	Q9XIN7	3e-75	NAC40_ARATH; NAC domain-containing protein 40
TrEMBL	A0A2J6KAC3	0.0	A0A2J6KAC3_LACSA; Uncharacterized protein
STRING	EOY33354	1e-100	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G27300.1	1e-77	NTM1-like 8

Publications ? help Back to Top
Liang M, et al. Subcellular Distribution of NTL Transcription Factors in Arabidopsis thaliana. Traffic, 2015. 16(10): p. 1062-74 [PMID:26201836] Tian H, et al. NTL8 Regulates Trichome Formation in Arabidopsis by Directly Activating R3 MYB Genes TRY and TCL1. Plant Physiol., 2017. 174(4): p. 2363-2375 [PMID:28649093]