PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa010115

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NAC

Protein Properties

Length: 152aa MW: 18039 Da PI: 6.9596

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58671943	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	182.7	8.9e-57	7	136	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkg 97 +ppGfrFhPtdeelv++yL+kk+++++++l +vi+++d+yk+ePwdL++ ++ + e++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++s k+ Lsa010115 7 VPPGFRFHPTDEELVDYYLRKKINSRRIDL-DVIRDIDLYKIEPWDLQElcSLGTeEQNEWYFFSHKDKKYPTGTRTNRATTAGFWKATGRDKAIYS-KQ 104 69**************************.9***********954533332566**********************************.89 PP NAM 98 elvglkktLvfykgrapkgektdWvmheyrle 129 lvg++ktLvfykgrap+g+k+dW+mheyrle Lsa010115 105 DLVGMRKTLVFYKGRAPNGQKSDWIMHEYRLE 136 9***************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.27E-58	5	151	IPR003441	NAC domain
PROSITE profile	PS51005	56.668	7	152	IPR003441	NAC domain
Pfam	PF02365	8.8E-30	8	135	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 152 aa Download sequence Send to blast
MNTFSHVPPG FRFHPTDEEL VDYYLRKKIN SRRIDLDVIR DIDLYKIEPW DLQELCSLGT 60 EEQNEWYFFS HKDKKYPTGT RTNRATTAGF WKATGRDKAI YSKQDLVGMR KTLVFYKGRA 120 PNGQKSDWIM HEYRLETDEN ATTTQEEGWV VX

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	1e-49	6	135	14	140	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:16103214, PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:25148240}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023753276.1	1e-111	NAC domain-containing protein 7-like
Swissprot	Q9FWX2	8e-96	NAC7_ARATH; NAC domain-containing protein 7
TrEMBL	A0A2J6M1N0	1e-109	A0A2J6M1N0_LACSA; Uncharacterized protein
STRING	XP_008234394.1	1e-103	(Prunus mume)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12260.1	5e-78	NAC 007

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469]