PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa010275
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family HSF
Protein Properties Length: 486aa    MW: 53527.4 Da    PI: 4.9712
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-187a-Lactuca_sativa-7909PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind116.51.7e-36511432103
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl k+y++++d+++++++sws+++nsfvv+d+ efak++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k+ll++i 
     Lsa010275  51 FLVKTYDMVDDPATDNVVSWSATNNSFVVWDPPEFAKDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKHLLKTII 138
                   9********************999*****************************************999.........*******************9 PP

                   XXXXX CS
  HSF_DNA-bind  99 rkkse 103
                   r+ks+
     Lsa010275 139 RRKST 143
                   99986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.4E-4043135IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.08E-3647140IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.8E-6447140IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.9E-205174IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004479.3E-3251140IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.9E-2089101IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434090114IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.9E-20102114IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 486 aa     Download sequence    Send to blast
MALHIPKLDT TSIAMEARSY SNAAASAPDG GTAAPPPAPP PMSSVNAPPP FLVKTYDMVD  60
DPATDNVVSW SATNNSFVVW DPPEFAKDLL PKYFKHNNFS SFVRQLNTYG FRKVDPDRWE  120
FANEGFLRGQ KHLLKTIIRR KSTSGHHQPP PQPHQQTTSV SACVEVGKFG LEEEXRKAKK  180
RQKRPDARTC EIKTTTTKHR QPNAINGATP SRHGTKTATN DVIFSKSSQQ PGDSWHIFVQ  240
QQNESTKLKQ KEIKKEGYKE EDGGISDNSS DGRIVKYQPM MNDAAQAMLK QIMKLDTASP  300
RLGPFTSGVT LQEVNPPPAS GQPYLPSVTG VLSAPLQANS NVIATNQSPL AEGQQLPELP  360
ELPELPELSQ LQDMVPELYP ETQNLVDEKL QLEIGGFSPD VDVEWDNNLL TEMEKYLTAY  420
DPSWEQYIEG SPEVDTADDM DAGPGPGDDV MNGVDSKSSE SSECSRSQVQ QLTTQMGLLS  480
SNTRKS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A6e-274914418123Heat shock factor protein 1
5d5u_B7e-273714015129Heat shock factor protein 1
5d5v_B7e-273714015129Heat shock factor protein 1
5d5v_D7e-273714015129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1175183RKAKKRQKR
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023736203.10.0heat shock factor protein HSF8-like
SwissprotQ401521e-103HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLA0A2J6KA520.0A0A2J6KA52_LACSA; Uncharacterized protein
STRINGXP_009619930.11e-112(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17750.12e-70heat shock factor 1
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  3. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]