PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa012100
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ERF
Protein Properties Length: 147aa    MW: 16202.3 Da    PI: 10.006
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58662036PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP264.32.5e-202372255
        AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
               +y+GVr ++ +gr++AeIrdp   g ++r++lg+f+taeeAaka++ a+ +++g
  Lsa012100 23 HYRGVRKRP-WGRYAAEIRDP---GTKTRVWLGTFDTAEEAAKAYDTAAVNFRG 72
               7********.**********8...325**********************99997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103223.8682380IPR001471AP2/ERF domain
SuperFamilySSF541711.96E-222382IPR016177DNA-binding domain
CDDcd000182.44E-322382No hitNo description
Gene3DG3DSA:3.30.730.103.2E-322380IPR001471AP2/ERF domain
SMARTSM003801.8E-382386IPR001471AP2/ERF domain
PfamPF008472.0E-132372IPR001471AP2/ERF domain
PRINTSPR003679.6E-122435IPR001471AP2/ERF domain
PRINTSPR003679.6E-124662IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 147 aa     Download sequence    Send to blast
MVMKNNASKP VTEAKIPGVD QVHYRGVRKR PWGRYAAEIR DPGTKTRVWL GTFDTAEEAA  60
KAYDTAAVNF RGTKAKINFP PSIDDVDGQS PSQSSIVECS TSSLDGRPPF HRPLELDLTR  120
RLDVSVAGYQ LFHNGGQKTV AVVPHPR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A5e-232384567ATERF1
3gcc_A5e-232384567ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase/phosphatase cascade, and to be influenced by methyl-jasmonate. May regulate other AtERFs (By similarity). {ECO:0000250, ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:10792818, ECO:0000269|PubMed:12654868, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly induced by ethephon (ethylene-releasing compound) in buds and to lower extent in leaves. Strongly induced by cycloheximide and mechanical stimuli. Wounding leads to a both local and systemical transient expression, independently of ethylene, and through a de-novo-protein-synthesis-independent regulation. Not influenced by methyl-jasmonate. Induction by purified xylanase from Trichoderma viride (TvX) and another elicitor from Phytophthora infestans (PiE), that appears to be mediated by a protein kinase cascade, and to be negatively regulated by protein phosphatases. {ECO:0000269|PubMed:10652129, ECO:0000269|PubMed:12090623, ECO:0000269|PubMed:7756828, ECO:0000269|Ref.2}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023738258.11e-105ethylene-responsive transcription factor 4-like
SwissprotQ404772e-43ERF4_TOBAC; Ethylene-responsive transcription factor 4
TrEMBLA0A2J6K5J81e-104A0A2J6K5J8_LACSA; Uncharacterized protein
STRINGPGSC0003DMT4000689594e-43(Solanum tuberosum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G15210.13e-26ethylene responsive element binding factor 4
Publications ? help Back to Top
  1. Ogata T, et al.
    Involvement of NtERF3 in the cell death signalling pathway mediated by SIPK/WIPK and WRKY1 in tobacco plants.
    Plant Biol (Stuttg), 2015. 17(5): p. 962-72
    [PMID:25996234]