PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa012207

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

C2H2

Protein Properties

Length: 252aa MW: 26734.5 Da PI: 9.2257

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-28755	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.5	0.00091	102	124	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC+ C+k F + L H +H Lsa012207 102 YKCNVCDKAFGSYQALGGHKASH 124 9*********9999998888777 PP
2	zf-C2H2	13.5	0.00022	159	181	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C++sF++ L H r+H Lsa012207 159 HECSICHRSFPTGQALGGHKRRH 181 78*******************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13912	2.5E-13	101	126	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	6.19E-8	101	124	No hit	No description
SMART	SM00355	0.022	102	124	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.0E-4	102	124	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.593	102	129	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	104	124	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	6.19E-8	154	181	No hit	No description
Pfam	PF13912	1.2E-12	159	183	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	9.286	159	181	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.066	159	181	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	161	181	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 252 aa Download sequence Send to blast
MAVEALNSPT TATTXLFKQD SGNHLRYLDS WTKGKRSKRP RVDQPPTEEE YLAFCLMLLA 60 RGGRGGSGSG SGSDSAYVAP PQRANSPALS IIVPQETQRV VYKCNVCDKA FGSYQALGGH 120 KASHRKNNPA AAGAEIEQSA VTTTSSTSGT HGGGSGRSHE CSICHRSFPT GQALGGHKRR 180 HYEGVIGGGR ASSGITSSEG VGSTNSQRGF DLNLPALPEF LPGFVDEEVE SPHPTKRSRL 240 FPPVKLEIAT HQ

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. {ECO:0000269\|PubMed:12032082, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:17112521, ECO:0000269\|PubMed:18216250, ECO:0000269\|PubMed:20140232, ECO:0000269\|PubMed:8662738}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salt, cold and drought stresses. Down-regulated by gibberellin. {ECO:0000269\|PubMed:10806347, ECO:0000269\|PubMed:11351099, ECO:0000269\|PubMed:12837949, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:17112521, ECO:0000269\|PubMed:8662738}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023764915.1	0.0	zinc finger protein ZAT10-like
Swissprot	Q96289	3e-58	ZAT10_ARATH; Zinc finger protein ZAT10
TrEMBL	A0A2J6LB97	0.0	A0A2J6LB97_LACSA; Uncharacterized protein
STRING	XP_009630807.1	2e-81	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G27730.1	7e-55	salt tolerance zinc finger

Publications ? help Back to Top
Li C,Chang PP,Ghebremariam KM,Qin L,Liang Y Overexpression of tomato SpMPK3 gene in Arabidopsis enhances the osmotic tolerance. Biochem. Biophys. Res. Commun., 2014. 443(2): p. 357-62 [PMID:24275141] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Shi H,Chan Z The cysteine2/histidine2-type transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activated C-REPEAT-BINDING FACTOR pathway is essential for melatonin-mediated freezing stress resistance in Arabidopsis. J. Pineal Res., 2014. 57(2): p. 185-91 [PMID:24962049] Munekage YN,Inoue S,Yoneda Y,Yokota A Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana. Plant Cell Environ., 2015. 38(6): p. 1116-26 [PMID:25293694] van Buer J,Cvetkovic J,Baier M Cold regulation of plastid ascorbate peroxidases serves as a priming hub controlling ROS signaling in Arabidopsis thaliana. BMC Plant Biol., 2016. 16(1): p. 163 [PMID:27439459] Corrales AR, et al. Multifaceted role of cycling DOF factor 3 (CDF3) in the regulation of flowering time and abiotic stress responses in Arabidopsis. Plant Cell Environ., 2017. 40(5): p. 748-764 [PMID:28044345] Nguyen HM, et al. Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice. Front Plant Sci, 2017. 8: p. 1001 [PMID:28717360] Geilen K,Heilmann M,Hillmer S,Böhmer M WRKY43 regulates polyunsaturated fatty acid content and seed germination under unfavourable growth conditions. Sci Rep, 2017. 7(1): p. 14235 [PMID:29079824] Liu X, et al. Histone Deacetylase AtSRT1 Links Metabolic Flux and Stress Response in Arabidopsis. Mol Plant, 2017. 10(12): p. 1510-1522 [PMID:29107034] Huang K, et al. Arabidopsis calcium-dependent protein kinase AtCPK1 plays a positive role in salt/drought-stress response. Biochem. Biophys. Res. Commun., 2018. 498(1): p. 92-98 [PMID:29196259]