PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa012296
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family C2H2
Protein Properties Length: 303aa    MW: 33068.1 Da    PI: 4.7069
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58686170PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-7546PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.00047276299123
                EEETTTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCpdCgksFsrksnLkrHirt.H 23 
                ++C+ C++ F++   L +H +  H
  Lsa012296 276 HSCKSCNRNFKTEGALSSHNQAkH 299
                79*****************76555 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5015711.136276303IPR007087Zinc finger, C2H2
PROSITE patternPS000280278299IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 303 aa     Download sequence    Send to blast
MEFWGAEIKS GQSFDVVIGE GKVLHLSQAC LGEAKKETKE SVCMHMTMDG KKLVLGTLIP  60
EKIPQQLFDL VFDKDFKVSH NSKNSSIYLY GYKADNPADD NDDSEEFSSE DDEEEDLPLP  120
VANGKQEAKK EEKKAVVPKK EQKSSAAGKQ KVKIVEPEKD VKESDDDDDS DDSAAMSEDS  180
DDEDDEDSSD DEEDSDEEEE TPKKEQSGKK RQNESASKTP TEKKKTKIAA TPQKTEGKKS  240
GAVHIATPHP SKQAVAKTPA GGSKSNQKSP ATDGAHSCKS CNRNFKTEGA LSSHNQAKHS  300
ASK
Functional Description ? help Back to Top
Source Description
UniProtMediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). {ECO:0000250}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By fertilization. {ECO:0000269|PubMed:15082924}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023758092.10.0histone deacetylase HDT1 isoform X1
SwissprotQ6V9I61e-78HDT1_SOLCH; Histone deacetylase HDT1
TrEMBLA0A2J6LR311e-159A0A2J6LR31_LACSA; Uncharacterized protein
STRINGXP_009612087.12e-83(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G44750.22e-27histone deacetylase 3
Publications ? help Back to Top
  1. Lagacé M,Chantha SC,Major G,Matton DP
    Fertilization induces strong accumulation of a histone deacetylase (HD2) and of other chromatin-remodeling proteins in restricted areas of the ovules.
    Plant Mol. Biol., 2003. 53(6): p. 759-69
    [PMID:15082924]