PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa013315
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family TALE
Protein Properties Length: 331aa    MW: 37761 Da    PI: 4.9692
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-187a-Lactuca_sativa-16659PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox26.31.3e-082743082155
                HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
   Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                k +yp+++++  LA+++gL+++q+ +WF N+R ++
  Lsa013315 274 KWPYPTEADKIWLAESTGLDQKQINNWFINQRKRH 308
                569*****************************885 PP
2ELK346.6e-12228249122
        ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                ELK+ LlrK++g+++sLk+EFs
  Lsa013315 228 ELKDTLLRKFGGHISSLKHEFS 249
                9********************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012553.1E-2198142IPR005540KNOX1
PfamPF037902.1E-20100141IPR005540KNOX1
SMARTSM012563.5E-25149200IPR005541KNOX2
PfamPF037913.4E-23153199IPR005541KNOX2
PfamPF037891.6E-9228249IPR005539ELK domain
SMARTSM011884.3E-7228249IPR005539ELK domain
PROSITE profilePS5121310.092228248IPR005539ELK domain
PROSITE profilePS5007112.568248311IPR001356Homeobox domain
SuperFamilySSF466897.27E-20249324IPR009057Homeodomain-like
SMARTSM003892.2E-13250315IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.607.0E-27253312IPR009057Homeodomain-like
CDDcd000864.82E-13257312No hitNo description
PfamPF059202.0E-16268307IPR008422Homeobox KN domain
PROSITE patternPS000270286309IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 331 aa     Download sequence    Send to blast
MEEMHGFHSM SDYTIPPETN LISPSDYHGD HSTSVDHYRT FYGSGDLLSA TASIITEAVS  60
IAATPDQTLL PRRRSCRQRD QNRNGNISDD HHVDACDDII KARIASHPLY PKLLDAFIDC  120
QKLGAPPEMV CLLDEIRREN DVCMRNAAAS TCLGADPELD EFMETYCQVL GKYKSDLARP  180
FDEATVFLNN IETQLGNLCK DDGAVSSEEE FSGGETENTQ QVSREDQELK DTLLRKFGGH  240
ISSLKHEFSK KKKKGKLPNE ARQTLLEWWD SHYKWPYPTE ADKIWLAEST GLDQKQINNW  300
FINQRKRHWK PSENMHLAMM GSFSGQDYYD D
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023762234.10.0homeobox protein knotted-1-like 6
SwissprotQ84JS61e-116KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A2J6LHB60.0A0A2J6LHB6_LACSA; Uncharacterized protein
STRINGVIT_01s0127g00210.t011e-130(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-108KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]