PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa013788

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

HSF

Protein Properties

Length: 273aa MW: 30189.8 Da PI: 8.1809

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-20486	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	113	2e-35	10	101	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+y +++d++++++isw+eng++f+v+++ +fa+++Lp+ Fkh+nf+SFvRQLn+YgF+k+ ++ weF++++Fk+g++ell +i+ Lsa013788 10 FLTKTYLLVDDPATDDVISWNENGSTFIVWKTADFARDLLPNSFKHNNFSSFVRQLNTYGFRKTVPDK---------WEFANENFKRGQRELLIEIR 97 9*************************************************************9999.........**************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k+ Lsa013788 98 RRKT 101 97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.7E-36	3	94	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.2E-56	6	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	7.35E-32	7	99	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	2.5E-30	10	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-19	10	33	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-19	48	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-19	61	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 273 aa Download sequence Send to blast
MTNRSVPAPF LTKTYLLVDD PATDDVISWN ENGSTFIVWK TADFARDLLP NSFKHNNFSS 60 FVRQLNTYGF RKTVPDKWEF ANENFKRGQR ELLIEIRRRK TVQSSQAKPT GDGGPAQSPS 120 ISGDDLGSSS TSSPDSKNPG SVDTPTVEKL ENLSDENEKL KKEKRILTSE LAQMKKQCDD 180 LVAFLTQNVK VAPDYINRIM KGDAVVGEMA TATATVTAGD EFNDAGGKGE SFKLFGVFLK 240 EETKKRGFDE INISSGAQRK ELKISGQSTK VCN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	6e-25	5	101	25	131	Heat shock factor protein 1
5d5v_B	6e-25	5	101	25	131	Heat shock factor protein 1
5d5v_D	6e-25	5	101	25	131	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023767909.1	0.0	heat shock factor protein HSF24-like
Swissprot	P22335	1e-103	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A2J6L566	0.0	A0A2J6L566_LACSA; Uncharacterized protein
STRING	cassava4.1_013185m	1e-115	(Manihot esculenta)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	2e-76	heat shock factor 4

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]