PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa014131

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

HSF

Protein Properties

Length: 357aa MW: 41274.4 Da PI: 4.7489

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-19555	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	113.4	1.5e-35	16	107	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k ye+++d++++ lisws +++sf+v++e+ef++++LpkyFkhsn+aSF RQLn+YgF+k+++++ weF+++ F kg+k+ll++i+ Lsa014131 16 FLSKCYEMVDDPSTDALISWSPTSDSFIVWNESEFTSELLPKYFKHSNYASFQRQLNIYGFRKIDTDR---------WEFANEGFIKGQKHLLKSIN 103 9******************999*************************************999.........**************** PP XXXX CS HSF_DNA-bind 99 rkks 102 rkk Lsa014131 104 RKKV 107 86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	5.2E-37	10	100	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.7E-51	12	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	5.85E-33	13	105	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	2.3E-31	16	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.3E-18	16	39	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.3E-18	54	66	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.3E-18	67	79	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 357 aa Download sequence Send to blast
MVKKSSETGG LTIAPFLSKC YEMVDDPSTD ALISWSPTSD SFIVWNESEF TSELLPKYFK 60 HSNYASFQRQ LNIYGFRKID TDRWEFANEG FIKGQKHLLK SINRKKVTHV TPHQKVTQEK 120 APESKLIHVT THDENRYANL RKEVENLKTD KNALMQELVK QRQHQDNSQT KMLVLREQLK 180 GMEKNQHQML SFIVMAMQSP GFLAQLSTPV QTTWLKSESN SKTILKPVVE DTEDTEESVI 240 LPHEGAIVKY QPPVEFPQDG FEFELSSEEV KDLLKDFDPE VAFDERIESY DPFVIHDNGD 300 DMLDQLLSSP FSEKNKSVKD FIDEEHGFEE IGLESMDRFR VLTEEFEKSL SVSTMES

Sequence ? help Back to Top

Protein Sequence Length: 357 aa Download sequence Send to blast

MVKKSSETGG LTIAPFLSKC YEMVDDPSTD ALISWSPTSD SFIVWNESEF TSELLPKYFK  60
HSNYASFQRQ LNIYGFRKID TDRWEFANEG FIKGQKHLLK SINRKKVTHV TPHQKVTQEK  120
APESKLIHVT THDENRYANL RKEVENLKTD KNALMQELVK QRQHQDNSQT KMLVLREQLK  180
GMEKNQHQML SFIVMAMQSP GFLAQLSTPV QTTWLKSESN SKTILKPVVE DTEDTEESVI  240
LPHEGAIVKY QPPVEFPQDG FEFELSSEEV KDLLKDFDPE VAFDERIESY DPFVIHDNGD  300
DMLDQLLSSP FSEKNKSVKD FIDEEHGFEE IGLESMDRFR VLTEEFEKSL SVSTMES

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	1e-27	8	111	12	125	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE). {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by heat stress. {ECO:0000269\|PubMed:18064488}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023755917.1	0.0	heat stress transcription factor A-8
Swissprot	Q84T61	3e-74	HSFA1_ORYSJ; Heat stress transcription factor A-1
TrEMBL	A0A2J6LVJ0	0.0	A0A2J6LVJ0_LACSA; Uncharacterized protein
STRING	EOY01363	3e-94	(Theobroma cacao)

Publications ? help Back to Top
Chauhan H,Khurana N,Agarwal P,Khurana P Heat shock factors in rice (Oryza sativa L.): genome-wide expression analysis during reproductive development and abiotic stress. Mol. Genet. Genomics, 2011. 286(2): p. 171-87 [PMID:21792744]