PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa014241

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NF-YC

Protein Properties

Length: 259aa MW: 28827.5 Da PI: 4.8434

Description

NF-YC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-29436	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NF-YC	178.1	8.4e-56	78	182	1	102
NF-YC 1 qlksfwekq...iekatdfknhelPlarikkilkadedvkmisaeaPvllskacelfileltlrswlhaeenkrrtlkksdiaaavtrtdifdflvdivp 97 ql+sfw++q ie++tdfknh+lPlarikki+kadedv+misaeaP+++++ace+fileltlrsw+h+eenkrrtl+k+diaaa+trtdifdflvdivp Lsa014241 78 QLQSFWANQyreIENVTDFKNHSLPLARIKKIMKADEDVRMISAEAPIVFARACEMFILELTLRSWNHTEENKRRTLQKNDIAAAITRTDIFDFLVDIVP 177 89****99999************************************************************************************* PP NF-YC 98 rdelk 102 r+++k Lsa014241 178 REDIK 182 *9875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47113	6.87E-33	69	172	IPR009072	Histone-fold
Pfam	PF00808	2.4E-21	100	163	IPR003958	Transcription factor CBF/NF-Y/archaeal histone domain
Gene3D	G3DSA:1.10.20.10	1.3E-37	101	178	IPR009072	Histone-fold

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046982	Molecular Function	protein heterodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 259 aa Download sequence Send to blast
MDPQGHGQPQ SSNMMSSVTQ LSYATNPYES TQLSGTPGRV QVGGAIQATN QPTAAQLAQQ 60 QLAYQQIQQQ QQQQLQQQLQ SFWANQYREI ENVTDFKNHS LPLARIKKIM KADEDVRMIS 120 AEAPIVFARA CEMFILELTL RSWNHTEENK RRTLQKNDIA AAITRTDIFD FLVDIVPRED 180 IKDEGMTSMP AVTVPVGGPS DAFPYYYMPA QQSPQSGAPG MMSNKAMLDP ALYAQQAPPY 240 MGPAIWPPPP QQPQSPSDS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5g49_B	6e-62	86	178	3	95	NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT C-3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	150	156	RRTLQKN

Functional Description ? help Back to Top
Source	Description
UniProt	Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity). Interacts with REF6 to directly regulate SOC1 transcription in response to flowering signals from photoperiod and gibberellic acid pathways (PubMed:25105952). {ECO:0000250, ECO:0000269\|PubMed:25105952}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023761221.1	0.0	nuclear transcription factor Y subunit C-9-like
Swissprot	Q8L4B2	2e-79	NFYC9_ARATH; Nuclear transcription factor Y subunit C-9
TrEMBL	A0A2J6LJI8	0.0	A0A2J6LJI8_LACSA; Uncharacterized protein
STRING	XP_008246497.1	1e-128	(Prunus mume)

Publications ? help Back to Top
Hwang YH, et al. Functional conservation of rice OsNF-YB/YC and Arabidopsis AtNF-YB/YC proteins in the regulation of flowering time. Plant Cell Rep., 2016. 35(4): p. 857-65 [PMID:26754793] Liu X, et al. The NF-YC-RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 12768 [PMID:27624486] Myers ZA, et al. NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana. PLoS Genet., 2016. 12(9): p. e1006333 [PMID:27685091] Tang Y, et al. Arabidopsis NF-YCs Mediate the Light-Controlled Hypocotyl Elongation via Modulating Histone Acetylation. Mol Plant, 2017. 10(2): p. 260-273 [PMID:27876642] Zhao H, et al. The Arabidopsis thaliana Nuclear Factor Y Transcription Factors. Front Plant Sci, 2016. 7: p. 2045 [PMID:28119722] Gnesutta N, et al. CONSTANS Imparts DNA Sequence Specificity to the Histone Fold NF-YB/NF-YC Dimer. Plant Cell, 2017. 29(6): p. 1516-1532 [PMID:28526714] Bi C,Ma Y,Wang XF,Zhang DP Overexpression of the transcription factor NF-YC9 confers abscisic acid hypersensitivity in Arabidopsis. Plant Mol. Biol., 2017. 95(4-5): p. 425-439 [PMID:28924726] Liu X, et al. Temporal-Specific Interaction of NF-YC and CURLY LEAF during the Floral Transition Regulates Flowering. Plant Physiol., 2018. 177(1): p. 105-114 [PMID:29599268]