PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa014286

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

C2H2

Protein Properties

Length: 396aa MW: 44735.2 Da PI: 8.0857

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58688676	PU_ref	Unigene	View CDS
PUT-187a-Lactuca_sativa-22319	PU_unref	plantGDB	View CDS
PUT-187a-Lactuca_sativa-24005	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.8	4.5e-06	67	89	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+C++C++ F r nL+ H r+H Lsa014286 67 YVCEICNQGFQRDQNLQMHRRRH 89 9*********************9 PP
2	zf-C2H2	16.3	2.8e-05	144	166	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k + +s++k H++t+ Lsa014286 144 WVCEKCSKGYAVQSDYKAHLKTC 166 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.04E-5	66	89	No hit	No description
SMART	SM00355	0.0052	67	89	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.4E-5	67	89	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.97	67	89	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	69	89	IPR007087	Zinc finger, C2H2
SMART	SM00355	210	108	138	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.2E-4	135	165	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.04E-5	139	164	No hit	No description
SMART	SM00355	60	144	171	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 396 aa Download sequence Send to blast
MFDNHLHHHH FTATHGPGPG PSSSSDLFSS PDNGLPSKRK RRPAGTPDPD AEVVSLSPKI 60 LLESDQYVCE ICNQGFQRDQ NLQMHRRRHK VPWKLLKRDS PEVKKRVFVC PEPSCLHHDP 120 CHALGDLVGI KKHFRRKHSN NKQWVCEKCS KGYAVQSDYK AHLKTCGTRG HSCDCGRVFS 180 RVESFIEHQD ACTIRRIHSD LPTFQPACSS RTASSTSPSN DKILTSIPTM ARSHHRQPPP 240 QTVFSQSQED MQNNLELQLL PSLSLYEQNN NNQNHLNLSI GNGVCLQKEE EMKMALADQA 300 FAEDARQQAK KQIEMAEMEF ENAKRIRQQA QVELERAKIL REQATRKISS TMLEITCYSC 360 RQRFEASSNN FGATTADETS IAPSYMSSAV TEGEGD

Sequence ? help Back to Top

Protein Sequence Length: 396 aa Download sequence Send to blast

MFDNHLHHHH FTATHGPGPG PSSSSDLFSS PDNGLPSKRK RRPAGTPDPD AEVVSLSPKI  60
LLESDQYVCE ICNQGFQRDQ NLQMHRRRHK VPWKLLKRDS PEVKKRVFVC PEPSCLHHDP  120
CHALGDLVGI KKHFRRKHSN NKQWVCEKCS KGYAVQSDYK AHLKTCGTRG HSCDCGRVFS  180
RVESFIEHQD ACTIRRIHSD LPTFQPACSS RTASSTSPSN DKILTSIPTM ARSHHRQPPP  240
QTVFSQSQED MQNNLELQLL PSLSLYEQNN NNQNHLNLSI GNGVCLQKEE EMKMALADQA  300
FAEDARQQAK KQIEMAEMEF ENAKRIRQQA QVELERAKIL REQATRKISS TMLEITCYSC  360
RQRFEASSNN FGATTADETS IAPSYMSSAV TEGEGD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	6e-18	142	192	5	55	Zinc finger protein JACKDAW
5b3h_F	6e-18	142	192	5	55	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in inflorescence stems gravitropism, probably by regulating starch accumulation in amyloplasts of graviperceptive cells. Required for stem circumnutation movements. Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602). Acts cooperatively with IDD16 to control silique and branche orientation (PubMed:24039602). Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602). {ECO:0000269\|PubMed:16813575, ECO:0000269\|PubMed:18259878, ECO:0000269\|PubMed:24039602, ECO:0000269\|PubMed:9210330}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by auxin. {ECO:0000269\|PubMed:24039602}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023734536.1	0.0	protein SHOOT GRAVITROPISM 5-like
Swissprot	F4IPE3	1e-153	IDD15_ARATH; Zinc finger protein SHOOT GRAVITROPISM 5
TrEMBL	A0A2J6KDT5	0.0	A0A2J6KDT5_LACSA; Uncharacterized protein
STRING	EOY01264	0.0	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68130.1	1e-138	indeterminate(ID)-domain 14

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kim JY,Ryu JY,Baek K,Park CM High temperature attenuates the gravitropism of inflorescence stems by inducing SHOOT GRAVITROPISM 5 alternative splicing in Arabidopsis. New Phytol., 2016. 209(1): p. 265-79 [PMID:26256266] Ryu JY,Kim JY,Park CM Adaptive thermal control of stem gravitropism through alternative RNA splicing in Arabidopsis. Plant Signal Behav, 2015. 10(11): p. e1093715 [PMID:26452406] Qu Y, et al. Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis. J. Exp. Bot., 2017. 68(17): p. 4851-4867 [PMID:28992128] Shi H, et al. Zinc finger of Arabidopsis thaliana 6 is involved in melatonin-mediated auxin signaling through interacting INDETERMINATE DOMAIN15 and INDOLE-3-ACETIC ACID 17. J. Pineal Res., 2018. 65(2): p. e12494 [PMID:29607541]