PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa014378

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NAC

Protein Properties

Length: 369aa MW: 41924.6 Da PI: 7.053

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58678181	PU_unref	Unigene	View CDS
PUT-187a-Lactuca_sativa-16258	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	170.1	7e-53	10	140	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk.k 96 +ppGfrFhPtdeel+ +yL+kkv+ + ++l +vi+evd++k+ePwdL+ k ++ + ++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++ + Lsa014378 10 VPPGFRFHPTDEELLYYYLRKKVSYEAIDL-DVIREVDLNKLEPWDLKdKcRIGSgPQNEWYFFSHKDKKYPTGTRTNRATTAGFWKATGRDKAIHLLsN 108 69**************************.9***********943444443456********************************98658 PP NAM 97 gelvglkktLvfykgrapkgektdWvmheyrl 128 ++ +g++ktLvfy+grap+g+ktdW+mheyrl Lsa014378 109 SKRIGMRKTLVFYTGRAPHGQKTDWIMHEYRL 140 899*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	2.75E-59	5	166	IPR003441	NAC domain
PROSITE profile	PS51005	58.504	10	166	IPR003441	NAC domain
Pfam	PF02365	5.8E-28	11	140	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 369 aa Download sequence Send to blast
MDTGNGQLSV PPGFRFHPTD EELLYYYLRK KVSYEAIDLD VIREVDLNKL EPWDLKDKCR 60 IGSGPQNEWY FFSHKDKKYP TGTRTNRATT AGFWKATGRD KAIHLLSNSK RIGMRKTLVF 120 YTGRAPHGQK TDWIMHEYRL DDQYSNAATP SEVQEDGWVV CRVFKKKNHN MRSPFQADDL 180 QQEDDHQQLI DQDTNKNGSG GGHSLHLQAL HGYECNMTSN TTLFEGSMHL PPLLTSPPDH 240 TPYFLAPRQS NEASTMMIND MDCSRNLLSL MSASRAGCGT CSSGHNQRTQ DKPLLATSNL 300 TADWSFLDKL LASNPHHHSG ITFDNHHHQG TCNDPSSSQA FHHPDVSATS HIFPFHYHGY 360 ETEVLKFSK

Sequence ? help Back to Top

Protein Sequence Length: 369 aa Download sequence Send to blast

MDTGNGQLSV PPGFRFHPTD EELLYYYLRK KVSYEAIDLD VIREVDLNKL EPWDLKDKCR  60
IGSGPQNEWY FFSHKDKKYP TGTRTNRATT AGFWKATGRD KAIHLLSNSK RIGMRKTLVF  120
YTGRAPHGQK TDWIMHEYRL DDQYSNAATP SEVQEDGWVV CRVFKKKNHN MRSPFQADDL  180
QQEDDHQQLI DQDTNKNGSG GGHSLHLQAL HGYECNMTSN TTLFEGSMHL PPLLTSPPDH  240
TPYFLAPRQS NEASTMMIND MDCSRNLLSL MSASRAGCGT CSSGHNQRTQ DKPLLATSNL  300
TADWSFLDKL LASNPHHHSG ITFDNHHHQG TCNDPSSSQA FHHPDVSATS HIFPFHYHGY  360
ETEVLKFSK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	6e-51	7	168	14	167	NO APICAL MERISTEM PROTEIN
1ut4_B	6e-51	7	168	14	167	NO APICAL MERISTEM PROTEIN
1ut7_A	6e-51	7	168	14	167	NO APICAL MERISTEM PROTEIN
1ut7_B	6e-51	7	168	14	167	NO APICAL MERISTEM PROTEIN
3swm_A	7e-51	7	168	17	170	NAC domain-containing protein 19
3swm_B	7e-51	7	168	17	170	NAC domain-containing protein 19
3swm_C	7e-51	7	168	17	170	NAC domain-containing protein 19
3swm_D	7e-51	7	168	17	170	NAC domain-containing protein 19
3swp_A	7e-51	7	168	17	170	NAC domain-containing protein 19
3swp_B	7e-51	7	168	17	170	NAC domain-containing protein 19
3swp_C	7e-51	7	168	17	170	NAC domain-containing protein 19
3swp_D	7e-51	7	168	17	170	NAC domain-containing protein 19
4dul_A	6e-51	7	168	14	167	NAC domain-containing protein 19
4dul_B	6e-51	7	168	14	167	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription regulator. Together with BRN1 and BRN2, regulates cellular maturation of root cap. Represses stem cell-like divisions in the root cap daughter cells, and thus promotes daughter cell fate. Inhibits expression of its positive regulator FEZ in a feedback loop for controlled switches in cell division plane. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269\|PubMed:19081078, ECO:0000269\|PubMed:20197506}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By FEZ in oriented-divised root cap stem cells. {ECO:0000269\|PubMed:19081078}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023742392.1	0.0	NAC domain-containing protein 76-like
Swissprot	Q9MA17	1e-107	SMB_ARATH; Protein SOMBRERO
TrEMBL	A0A2J6JWK3	0.0	A0A2J6JWK3_LACSA; Uncharacterized protein
STRING	XP_006493793.1	1e-137	(Citrus sinensis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79580.3	2e-98	NAC family protein

Publications ? help Back to Top
Fendrych M, et al. Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis. Curr. Biol., 2014. 24(9): p. 931-40 [PMID:24726156] Bennett T,van den Toorn A,Willemsen V,Scheres B Precise control of plant stem cell activity through parallel regulatory inputs. Development, 2014. 141(21): p. 4055-64 [PMID:25256342] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Kamiya M, et al. Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis. Development, 2016. 143(21): p. 4063-4072 [PMID:27803060]