PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa014931

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

WRKY

Protein Properties

Length: 325aa MW: 35814.8 Da PI: 7.3906

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-54118	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	94.6	6.9e-30	162	221	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dgy+WrKYGqK+ ++++ pr+Y++C++a +Cpvkkkv+rs ed+++++ tYegeHnh+ Lsa014931 162 VKDGYQWRKYGQKVTRDNPSPRAYFKCSHApTCPVKKKVQRSVEDQSILVATYEGEHNHP 221 58*************************99**************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	9.9E-29	156	222	IPR003657	WRKY domain
PROSITE profile	PS50811	25.327	161	223	IPR003657	WRKY domain
SuperFamily	SSF118290	8.37E-25	161	222	IPR003657	WRKY domain
SMART	SM00774	5.4E-34	162	222	IPR003657	WRKY domain
Pfam	PF03106	1.5E-24	163	221	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 325 aa Download sequence Send to blast
MEYTSLVDTS LDLNSNPSHF LSLVPKQEVQ SSFNIELGLK MSSVNDQDAS ELVEELNRVS 60 AENKKLTEML TVMCENYNAL QNHLADYISK NPAPSDSATN NNPNKRKPEN PVNQIINNER 120 GNSESSSSDE DSCKKPRQEQ NLKAKISRVC VRTEASDTGL LVKDGYQWRK YGQKVTRDNP 180 SPRAYFKCSH APTCPVKKKV QRSVEDQSIL VATYEGEHNH PNQAKNEQAG SCLSRTVATT 240 TLGSVPCSAS LSSSGPTITL DLTKPVSNAS DEQKVGGNRR VDTPEFQQFL VDQMASSLTK 300 DPSFKAALAA AISGRMVQQN QSQKW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	2e-19	147	220	1	71	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250\|UniProtKB:Q9SUP6}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023744098.1	0.0	probable WRKY transcription factor 40
Swissprot	Q9SAH7	3e-94	WRK40_ARATH; Probable WRKY transcription factor 40
TrEMBL	A0A2J6JT24	0.0	A0A2J6JT24_LACSA; Uncharacterized protein
STRING	cassava4.1_011696m	1e-122	(Manihot esculenta)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G80840.1	2e-89	WRKY DNA-binding protein 40

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhang Y, et al. Regulation of oncogene expression in T-DNA-transformed host plant cells. PLoS Pathog., 2015. 11(1): p. e1004620 [PMID:25615824] Geilen K,Böhmer M Dynamic subnuclear relocalisation of WRKY40 in response to Abscisic acid in Arabidopsis thaliana. Sci Rep, 2015. 5: p. 13369 [PMID:26293691] Geilen K,Böhmer M Dynamic subnuclear relocalization of WRKY40, a potential new mechanism of ABA-dependent transcription factor regulation. Plant Signal Behav, 2015. 10(11): p. e1106659 [PMID:26479147] Van Aken O, et al. Mitochondrial and Chloroplast Stress Responses Are Modulated in Distinct Touch and Chemical Inhibition Phases. Plant Physiol., 2016. 171(3): p. 2150-65 [PMID:27208304] Carrió-Seguí À,Romero P,Sanz A,Peñarrubia L Interaction Between ABA Signaling and Copper Homeostasis in Arabidopsis thaliana. Plant Cell Physiol., 2016. 57(7): p. 1568-1582 [PMID:27328696] Lu K, et al. Overexpression of an Arabidopsis cysteine-rich receptor-like protein kinase, CRK5, enhances abscisic acid sensitivity and confers drought tolerance. J. Exp. Bot., 2016. 67(17): p. 5009-27 [PMID:27406784] Birkenbihl RP,Kracher B,Roccaro M,Somssich IE Induced Genome-Wide Binding of Three Arabidopsis WRKY Transcription Factors during Early MAMP-Triggered Immunity. Plant Cell, 2017. 29(1): p. 20-38 [PMID:28011690] Lee MH,Jeon HS,Kim HG,Park OK An Arabidopsis NAC transcription factor NAC4 promotes pathogen-induced cell death under negative regulation by microRNA164. New Phytol., 2017. 214(1): p. 343-360 [PMID:28032643] Zhang S, et al. The Arabidopsis Mitochondrial Protease FtSH4 Is Involved in Leaf Senescence via Regulation of WRKY-Dependent Salicylic Acid Accumulation and Signaling. Plant Physiol., 2017. 173(4): p. 2294-2307 [PMID:28250067] Cheng P, et al. The ERA-Related GTPase AtERG2 Associated with Mitochondria 18S RNA Is Essential for Early Embryo Development in Arabidopsis. Front Plant Sci, 2018. 9: p. 182 [PMID:29497438]