PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa015620

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

G2-like

Protein Properties

Length: 322aa MW: 35052 Da PI: 6.0821

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-37092	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	95.1	5.5e-30	153	206	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G ++A+Pkti++lm+v+gLt+e+v+SHLQkYRl Lsa015620 153 RPRLVWTPQLHKRFVDVVAHL-GVKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 206 59*****************.9*****************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	1.72E-19	150	210	IPR009057	Homeodomain-like
PROSITE profile	PS51294	11.41	150	209	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	1.1E-30	151	211	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	2.5E-23	154	206	IPR006447	Myb domain, plants
Pfam	PF00249	1.5E-8	156	205	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 322 aa Download sequence Send to blast
MGEEVRITDY DVGGEDDDRV LEWEAGLPNA DDLMPLSQSL VPVELASAFS ITPEPQRSMI 60 DVNRASQNTL SNLRGQTVKQ TLNKFNGFKS FGDDKGDEMV AEGDETADLT GDCSDSRKLR 120 RVDSGGTGAI GGAGEEADSA LRADDSSART SKRPRLVWTP QLHKRFVDVV AHLGVKNAVP 180 KTIMQLMNVE GLTRENVASH LQKYRLYLKR MQGLSNEGPS SSDHLFASTP VPQSLHESSG 240 GGNGNSHAPV PIPMPYPPQM VPMPYPPPQM VSHPGGAGGG AYHHGFDSHS HPYNMMMQQR 300 DWSGSKFASV SPYQHRMTPN DK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	4e-35	153	209	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023759032.1	0.0	transcription factor PCL1
Swissprot	Q9SNB4	3e-84	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A2J6LP22	0.0	A0A2J6LP22_LACSA; Uncharacterized protein
STRING	VIT_06s0004g05120.t01	1e-124	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	4e-78	G2-like family protein

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]