PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa015983
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family E2F/DP
Protein Properties Length: 349aa    MW: 38202.8 Da    PI: 8.2362
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58687248PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-49034PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP862.9e-27105186371
    E2F_TDP   3 eksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                +++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+a+++i+k +k+ei+w+g
  Lsa015983 105 GRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfadprnsdqppdqqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWRG 186
                68********...*****999*******************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.4E-4699191IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.4E-34103186IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.5E-25106186IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.54E-21106187IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144581.11E-43191294IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440744.18E-42192302No hitNo description
SMARTSM011384.7E-65193347IPR014889Transcription factor DP, C-terminal
PfamPF087811.3E-40194302IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 349 aa     Download sequence    Send to blast
MVRMGSNDNL ENVVGSTNPL SVVSRGGATR SWGTTASGQS VSTSGSVGSP STRSEAAMAA  60
TPASDNTFMR LNHLDIHADD AGSQGAAGNK KKKRGQRATG GDKVGRGLRQ FSMKVCEKVE  120
SKGRTTYNEV ADELVAEFAD PRNSDQPPDQ QQYDEKNIRR RVYDALNVLM AMDIISKDKK  180
EIQWRGLPRT TLNDIEELKS ERIAIKNRIE KKAAYLRELE DQHIGLQNLI QRNEQLYGSG  240
NAPSGGVALP FILVQTRPHA TVEVEISEDM QLVHFDFNST PFELHDDNYV LKAMKFGDGT  300
KNVCTEGSVG SSMFEGGVPM QPRSTITHGR PPPSPPLPGI LKGRVKHEN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B2e-3797188190PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023745950.10.0transcription factor-like protein DPB
SwissprotQ9FNY21e-161DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A2J6JP800.0A0A2J6JP80_LACSA; Uncharacterized protein
STRINGXP_010241817.10.0(Nelumbo nucifera)