PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa016895

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NAC

Protein Properties

Length: 339aa MW: 38052.6 Da PI: 9.1415

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-41474	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	168.7	2e-52	14	139	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelv 100 lppGfrF Ptdeel+v+yL++kv+g++++l ++i+++d+yk++Pw+Lp+k+ +ekewyfFs+rd+ky++g+r+nr++ sgyWkatg+dk +++ +g+ v Lsa016895 14 LPPGFRFFPTDEELLVQYLCRKVAGHDFSL-QIIADIDLYKFDPWELPSKAMFGEKEWYFFSPRDRKYPNGSRPNRVAGSGYWKATGTDKVITT-GGRRV 111 79*************************9.89***********8777899*********************************99.999 PP NAM 101 glkktLvfykgrapkgektdWvmheyrl 128 g+kk Lvfy g+apkg+kt+W+mheyrl Lsa016895 112 GIKKALVFYVGKAPKGNKTNWIMHEYRL 139 **************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.01E-67	9	163	IPR003441	NAC domain
PROSITE profile	PS51005	61.277	14	162	IPR003441	NAC domain
Pfam	PF02365	6.2E-26	15	139	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 339 aa Download sequence Send to blast
MGLPVTDPMT QLSLPPGFRF FPTDEELLVQ YLCRKVAGHD FSLQIIADID LYKFDPWELP 60 SKAMFGEKEW YFFSPRDRKY PNGSRPNRVA GSGYWKATGT DKVITTGGRR VGIKKALVFY 120 VGKAPKGNKT NWIMHEYRLS EPQRKNGSSR LDDWVLCRIY KKNSSAQKHI SGGAPTTEQS 180 HGSSSSSSSQ FDDVLESLPE IEDRFFNLPR INSLKTFQQE DQKVNLQKFD SGNYDWASIA 240 AFGLPEPATG SQAPTTANTA MNVIPSMAPA TTYTMDATFG RSVEDEVQSG IRSQRVEHPG 300 SGYFQSNLNQ FTQSQGFSNT MDPFGIRYPT QQGNLGFRR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	1e-109	1	168	4	171	NO APICAL MERISTEM PROTEIN
1ut4_B	1e-109	1	168	4	171	NO APICAL MERISTEM PROTEIN
1ut7_A	1e-109	1	168	4	171	NO APICAL MERISTEM PROTEIN
1ut7_B	1e-109	1	168	4	171	NO APICAL MERISTEM PROTEIN
3swm_A	1e-109	1	168	7	174	NAC domain-containing protein 19
3swm_B	1e-109	1	168	7	174	NAC domain-containing protein 19
3swm_C	1e-109	1	168	7	174	NAC domain-containing protein 19
3swm_D	1e-109	1	168	7	174	NAC domain-containing protein 19
3swp_A	1e-109	1	168	7	174	NAC domain-containing protein 19
3swp_B	1e-109	1	168	7	174	NAC domain-containing protein 19
3swp_C	1e-109	1	168	7	174	NAC domain-containing protein 19
3swp_D	1e-109	1	168	7	174	NAC domain-containing protein 19
4dul_A	1e-109	1	168	4	171	NAC domain-containing protein 19
4dul_B	1e-109	1	168	4	171	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). Involved in jasmonate- and coronatine-mediated stomatal reopening in response to Pseudomonas syringae pv tomato DC3000 infection (PubMed:25005917). Regulates the expression of threonine deaminase 2 (TD2) through promoter binding (PubMed:28733419). {ECO:0000269\|PubMed:25005917, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by jasmonate (JA) (PubMed:25005917, PubMed:28733419, PubMed:30610166). Induced by wounding (PubMed:28733419, PubMed:25005917). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced by coronatine (PubMed:25005917). {ECO:0000269\|PubMed:25005917, ECO:0000269\|PubMed:28733419, ECO:0000269\|PubMed:30610166}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023756347.1	0.0	NAC domain-containing protein 72-like
Swissprot	A0A3Q7HH64	1e-158	JA2L_SOLLC; NAC domain-containing protein JA2L
TrEMBL	A0A2J6LUI4	0.0	A0A2J6LUI4_LACSA; Uncharacterized protein
STRING	XP_006464708.1	1e-159	(Citrus sinensis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G27410.2	1e-125	NAC family protein

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419] Liu Y, et al. MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop. Plant Cell, 2019. 31(1): p. 106-127 [PMID:30610166]