PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa016951

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

WRKY

Protein Properties

Length: 221aa MW: 25820.4 Da PI: 7.9163

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58678522	PU_ref	Unigene	View CDS
PUT-187a-Lactuca_sativa-2942	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	103.5	1.2e-32	147	205	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 ldDgy+WrKYGqK+vk+s +prsYYrCt+++C+vkk+ver +ed ++v++tYeg+Hnh+ Lsa016951 147 LDDGYKWRKYGQKVVKNSLHPRSYYRCTHSNCRVKKRVERLSEDCRMVITTYEGRHNHS 205 59********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.9E-34	132	205	IPR003657	WRKY domain
SuperFamily	SSF118290	1.11E-28	139	205	IPR003657	WRKY domain
PROSITE profile	PS50811	29.608	142	204	IPR003657	WRKY domain
SMART	SM00774	6.5E-38	147	206	IPR003657	WRKY domain
Pfam	PF03106	2.5E-25	148	204	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 221 aa Download sequence Send to blast
MEGSERGLAN FDLQVSSFQN PIHDHIGFAH FQDHHHNHDP HQTQVLRFLP PTLSLPQLSQ 60 PPHHTTTTTS AEAADFHREA PSVHRDSWHK EQVGSLDPKS VNEEKCADDN TSWWRSSSNP 120 EKGRTKMRRK LREPRFCFQT RSDVDVLDDG YKWRKYGQKV VKNSLHPRSY YRCTHSNCRV 180 KKRVERLSED CRMVITTYEG RHNHSPCDDS NSSEHECFTS F

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	3e-26	138	204	8	74	Probable WRKY transcription factor 4
2lex_A	3e-26	138	204	8	74	Probable WRKY transcription factor 4
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023772780.1	1e-166	probable WRKY transcription factor 12
Swissprot	Q93WY4	2e-63	WRK12_ARATH; Probable WRKY transcription factor 12
TrEMBL	A0A2J6KU46	1e-165	A0A2J6KU46_LACSA; Uncharacterized protein
STRING	EOX96509	1e-92	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44745.1	1e-65	WRKY family protein

Publications ? help Back to Top
Yu Y, et al. MlWRKY12, a novel Miscanthus transcription factor, participates in pith secondary cell wall formation and promotes flowering. Plant Sci., 2013. 212: p. 1-9 [PMID:24094048] Yang L, et al. PtrWRKY19, a novel WRKY transcription factor, contributes to the regulation of pith secondary wall formation in Populus trichocarpa. Sci Rep, 2016. 6: p. 18643 [PMID:26819184] Li W,Wang H,Yu D Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions. Mol Plant, 2016. 9(11): p. 1492-1503 [PMID:27592586] Han Y, et al. WRKY12 represses GSH1 expression to negatively regulate cadmium tolerance in Arabidopsis. Plant Mol. Biol., 2019. 99(1-2): p. 149-159 [PMID:30617455]