PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa017920
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family HD-ZIP
Protein Properties Length: 836aa    MW: 92029.2 Da    PI: 5.9745
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58696056PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-40262PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.51.1e-181876357
               --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
   Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
               k  ++t+eq+e+Le+l++ +++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Lsa017920 18 KYVRYTPEQVEALERLYHDCPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 76
               5679*****************************************************97 PP
2START176.31.9e-551623702205
                HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEXXT CS
      START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvaelq 99 
                +aee+++e+++ka+ ++  Wv+++ +++g++++ +++ s++++g a+ra+g+v  +++++ve+l d++  W ++++++++l+v+++g  g+++l +++l+
  Lsa017920 162 IAEETLTEFLSKATGTAVEWVQMPGMKPGPDSIGIIAISHGCTGVASRACGLVGLEPTRVVEILKDRP-SWCRDCRAVDVLNVLTTGsnGTIELLYMQLY 260
                789*******************************************************9998888888.******************************* PP

                TXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHH CS
      START 100 alsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegakt 195
                a+++l+p Rdf+ +Ry+  l++g++v++++S++++q+ p+    +++vRa++lpSg+li+p+++g+s +++v+hvdl++  ++++lr+l+ s++  +++t
  Lsa017920 261 APTTLAPaRDFWLLRYTSALEDGSLVVCERSLNNTQNGPSmppVPHFVRAKMLPSGYLIRPCDGGGSIIHIVDHVDLESGNVPEVLRPLYDSSTLLAQRT 360
                **************************************999999******************************************************** PP

                HHHHTXXXXX CS
      START 196 wvatlqrqce 205
                ++a+l+++++
  Lsa017920 361 TLAALRQLRQ 370
                ******9876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.6291377IPR001356Homeobox domain
SMARTSM003891.3E-151581IPR001356Homeobox domain
SuperFamilySSF466895.99E-171681IPR009057Homeodomain-like
CDDcd000861.77E-161878No hitNo description
PfamPF000463.2E-161976IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.1E-182076IPR009057Homeodomain-like
CDDcd146861.52E-670109No hitNo description
PROSITE profilePS5084827.029152367IPR002913START domain
CDDcd088751.62E-78156371No hitNo description
SMARTSM002346.0E-40161371IPR002913START domain
Gene3DG3DSA:3.30.530.208.4E-23161367IPR023393START-like domain
SuperFamilySSF559611.02E-36161371No hitNo description
PfamPF018526.7E-53162370IPR002913START domain
PfamPF086706.3E-49696836IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 836 aa     Download sequence    Send to blast
MAVSSACKGD PMGMDNGKYV RYTPEQVEAL ERLYHDCPKP SSLRRQQLIR ECPILSNIEP  60
KQIKVWFQNR RCREKQRKEA SRLQAVNRKL SAMNKLLMEE NDRLQKQVSN LVYENGYFRQ  120
QTQNTALATT DTSCESVVTS GQHHLTPQNP PRDASPAGLL SIAEETLTEF LSKATGTAVE  180
WVQMPGMKPG PDSIGIIAIS HGCTGVASRA CGLVGLEPTR VVEILKDRPS WCRDCRAVDV  240
LNVLTTGSNG TIELLYMQLY APTTLAPARD FWLLRYTSAL EDGSLVVCER SLNNTQNGPS  300
MPPVPHFVRA KMLPSGYLIR PCDGGGSIIH IVDHVDLESG NVPEVLRPLY DSSTLLAQRT  360
TLAALRQLRQ ISQEISQPMV TSWGRRPSAL RSLGQRMSRG FNEAINGFSD EGWSMMESDG  420
VDDVTVLVNS SPDKVMGAAP IYADGFPSIS NAILCAKASM LLQNVPPAIL TRFLREHRSE  480
WADSSIDGYS AASVKSGPCG LPMARNGNFG GQVILPLAHT IEHEEFMEVI KLENMSHYRA  540
EDMLMPADIF FLQLCSGVDE NSIGTSAELI FAPIDASFTD DAPLLPSGFR IIPINNVTNH  600
PSQNPTRDLA SALEVGPPGS RTPADYLGQS GPTKSVMTIA FQFAFEIHLQ ENIAAMARQY  660
VRSIIASVQR VALALSPSPF GPRSLQIPNG TPEAHMLTRW ICQSFRCFLG EDLFKTVDER  720
SDSMLKTLWH HSDAIMCCSL KAMPDFTFAN QAGLDMLETT LVSLQDITLD KIFDGGGRTN  780
VCSELPQVLQ QGFVCLPGGI CLTSMGRPVS YERAVAWKVL NDEESPHCIA FVFVNW
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269|PubMed:11402194, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165. {ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:8575317}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023729871.10.0homeobox-leucine zipper protein ATHB-8
RefseqXP_023729872.10.0homeobox-leucine zipper protein ATHB-8
SwissprotQ391230.0ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBLA0A2J6KP960.0A0A2J6KP96_LACSA; Uncharacterized protein
STRINGXP_008220092.10.0(Prunus mume)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32880.10.0homeobox gene 8
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M
    Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis.
    Planta, 2014. 239(5): p. 989-1001
    [PMID:24488524]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Liu S, et al.
    Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 388
    [PMID:26082787]
  7. Yamaguchi YL, et al.
    Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots.
    Front Plant Sci, 2017. 8: p. 1195
    [PMID:28747918]
  8. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]