PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa018110
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family C2H2
Protein Properties Length: 278aa    MW: 32035.2 Da    PI: 8.0602
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58678406PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-50109PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.80.00018321523
               TTTEEESSHHHHHHHHHHT CS
    zf-C2H2  5 dCgksFsrksnLkrHirtH 23
               dC+ s++rk++L+rH+  H
  Lsa018110  3 DCNHSYRRKDHLNRHLIQH 21
               9**************9877 PP
2zf-C2H214.69.7e-052651123
               EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
               ++C+  +C+  Fs + nL+rHi+  H
  Lsa018110 26 FECTikNCKSKFSIQGNLTRHIKEiH 51
               789999*****************988 PP
3zf-C2H218.17.1e-066892123
               EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
               y+Cp   Cgk+F   s L++H  +H
  Lsa018110 68 YTCPepGCGKVFQYASRLQKHKESH 92
               99*******************9998 PP
4zf-C2H215.54.9e-05159183223
                EET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                kC+   C+ +Fs +snL +H +  H
  Lsa018110 159 KCSfdGCDHTFSKRSNLAVHVKAaH 183
                799999***************9886 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM0035583221IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.602.6E-4223IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.27E-6753No hitNo description
Gene3DG3DSA:3.30.160.601.4E-42452IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0212651IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.8032656IPR007087Zinc finger, C2H2
PROSITE patternPS0002802851IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.7E-86092IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.26E-567120No hitNo description
SMARTSM003551.8E-46892IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.4066897IPR007087Zinc finger, C2H2
PROSITE patternPS0002807092IPR007087Zinc finger, C2H2
SMARTSM0035512100123IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280102123IPR007087Zinc finger, C2H2
SMARTSM0035522126147IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.77E-9141196No hitNo description
SMARTSM003550.0062158183IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.362158188IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.5E-6159185IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280160184IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.5E-5186211IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003554.9189215IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280191215IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 278 aa     Download sequence    Send to blast
MEDCNHSYRR KDHLNRHLIQ HQGKIFECTI KNCKSKFSIQ GNLTRHIKEI HDDDDSDSEA  60
TQEQKTTYTC PEPGCGKVFQ YASRLQKHKE SHVKLDTVEA LCGECMKYFT NEQCLKAHIQ  120
SCHQHINCEI CGSKHLKKNI KRHLRTHEKV VSEEKERIKC SFDGCDHTFS KRSNLAVHVK  180
AAHHQEKPFV CSVSGCGMRF AFKHVRDNHE KSGSHVYTIG DFVEGDDEFR SRERGGVKRK  240
LPGVIDALMR KRVLPINESD CIHGSDYISW LLSTGDED
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023768299.10.0transcription factor IIIA
SwissprotQ84MZ41e-101TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A2J6L4320.0A0A2J6L432_LACSA; Uncharacterized protein
STRINGVIT_08s0040g00240.t011e-122(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.11e-104transcription factor IIIA