PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa018562

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

HD-ZIP

Protein Properties

Length: 303aa MW: 34582.9 Da PI: 4.7119

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-46452	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.6	2.4e-19	65	118	3	56
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 k+++++++q++ Le+ Fe +++++ e++ + A+ lgL+ rqV +WFqNrRa++k Lsa018562 65 KKRRLSNHQVKSLEKIFEVDNKLDPERKVKVAQDLGLQPRQVAIWFQNRRARWK 118 56689************************************************9 PP
2	HD-ZIP_I/II	126	1.7e-40	65	155	2	92
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelk 92 kkrrls++qvk+LE+ Fe ++kL+perKv++a++Lglqprqva+WFqnrRAR+ktkqlE+dy+ Lk++ydalk++ ++Le+e+e++ +el Lsa018562 65 KKRRLSNHQVKSLEKIFEVDNKLDPERKVKVAQDLGLQPRQVAIWFQNRRARWKTKQLERDYNLLKSNYDALKHNYHKLEQEKESIINELI 155 9***********************************************************************************9998875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	8.98E-20	40	122	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.103	60	120	IPR001356	Homeobox domain
SMART	SM00389	2.1E-18	63	124	IPR001356	Homeobox domain
CDD	cd00086	3.44E-16	65	121	No hit	No description
Pfam	PF00046	1.4E-16	65	118	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	4.0E-19	67	127	IPR009057	Homeodomain-like
PRINTS	PR00031	5.5E-5	91	100	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	95	118	IPR017970	Homeobox, conserved site
PRINTS	PR00031	5.5E-5	100	116	IPR000047	Helix-turn-helix motif
Pfam	PF02183	2.6E-14	120	161	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 303 aa Download sequence Send to blast
MKRNFGCSDS LTHFLSHPLE GEMKAEEECL YNGEFQSMVD GSGSGSGGGD GEDYGGEETG 60 QFSDKKRRLS NHQVKSLEKI FEVDNKLDPE RKVKVAQDLG LQPRQVAIWF QNRRARWKTK 120 QLERDYNLLK SNYDALKHNY HKLEQEKESI INELIELKAK LHEETTERND EFENKENILF 180 LGSDPTNTNH EIYTSLNYEK TRKSLDLKDG FSDSDSSGVL NEENMNVSNA NGSSLLNIAT 240 FGLSSICSSS ATNSNHTEHI DPTRTYQEQS DPYLVSNVED ESCNIFLVDQ APNLCWYFRD 300 HTN

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	112	120	RRARWKTKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that acts as a positive regulator of ABA-responsiveness, mediating the inhibitory effect of ABA on growth during seedling establishment. Binds to the DNA sequence 5'-CAATNATTG-3'. {ECO:0000269\|PubMed:12678559}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by abscisic acid (ABA) and by salt stress. {ECO:0000269\|PubMed:12678559, ECO:0000269\|PubMed:16055682}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023769750.1	0.0	homeobox-leucine zipper protein ATHB-16-like
Swissprot	P46667	4e-46	ATHB5_ARATH; Homeobox-leucine zipper protein ATHB-5
TrEMBL	A0A2J6L0T8	0.0	A0A2J6L0T8_LACSA; Uncharacterized protein

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G40060.1	8e-47	homeobox protein 16

Publications ? help Back to Top
Cassan-Wang H, et al. Identification of novel transcription factors regulating secondary cell wall formation in Arabidopsis. Front Plant Sci, 2013. 4: p. 189 [PMID:23781226] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239] Stamm P, et al. The Transcription Factor ATHB5 Affects GA-Mediated Plasticity in Hypocotyl Cell Growth during Seed Germination. Plant Physiol., 2017. 173(1): p. 907-917 [PMID:27872245]