PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lus10000037

Organism

Linum usitatissimum

Taxonomic ID

4006

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum

Family

bHLH

Protein Properties

Length: 221aa MW: 25042.6 Da PI: 9.0276

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Lus10000037	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	42.9	9e-14	44	89	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YIk+L Lus10000037 44 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYIKEL 89 799*********************6.....5**************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	17.746	40	89	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.62E-19	43	113	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.34E-13	43	94	No hit	No description
Gene3D	G3DSA:4.10.280.10	7.7E-19	44	111	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.2E-11	44	89	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	9.8E-17	46	95	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 221 aa Download sequence Send to blast
MVDSDVDQSD LEPSVIKEVV VAEPEKRPRK RGRKPANGRE EPLNHVEAER QRREKLNQRF 60 YALRAVVPNV SKMDKASLLG DAISYIKELS SKLQLTESSK KELERQVESI RKQQPDYHQE 120 YNKKACSNEF GGKTKAIEMD IDVKIIGWDA MIRIQCSKEN HPAARLMAGL KELDLDVHHA 180 SVSVVNDLMI QQATVKMGSR FYTQEELRLA LSNKVGGDTR *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5gnj_A	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_B	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_E	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_F	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_G	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_I	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_M	6e-34	38	111	2	75	Transcription factor MYC2
5gnj_N	6e-34	38	111	2	75	Transcription factor MYC2
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	25	33	KRPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes (PubMed:15231736). Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371, PubMed:30518626). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). Acts synergistically with EOT1 in the transactivation of TPS5 (PubMed:24884371). Involved in type VI glandular trichome development (PubMed:30518626). Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes (PubMed:30518626). {ECO:0000269\|PubMed:15231736, ECO:0000269\|PubMed:24884371, ECO:0000269\|PubMed:30518626}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Lus10000037

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by methyl jasmonate and wounding. {ECO:0000269\|PubMed:15231736}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012076236.1	1e-109	transcription factor MYC2 isoform X1
Swissprot	A0A060KY90	1e-102	MYC1_SOLLC; Transcription factor MYC1
TrEMBL	A0A0A6ZA38	1e-111	A0A0A6ZA38_9ROSI; Transcription factor MYC2 (Fragment)
STRING	Lus10000037	1e-162	(Linum usitatissimum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2938	33	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17880.1	2e-83	bHLH family protein

Link Out ? help Back to Top
Phytozome	Lus10000037

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371] Xu J, et al. SlMYC1 Regulates Type VI Glandular Trichome Formation and Terpene Biosynthesis in Tomato Glandular Cells. Plant Cell, 2018. 30(12): p. 2988-3005 [PMID:30518626]