PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10014369
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family HSF
Protein Properties Length: 447aa    MW: 50311.2 Da    PI: 4.4332
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10014369genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind96.13.6e-30721802102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTT........XTTSEEEEESXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekksks........kekiweFkhksFkkgk 90 
                   Fl+k++++++d+ l+ +isw  +g+sfvv+d+ ef+++vLp+ Fkh+nf+SFvRQLn+Y  ++  + ++  ++        + + weF+++ F++g+
   Lus10014369  72 FLSKTFDLVDDQGLDPVISWGGRGESFVVWDPVEFSRTVLPRNFKHNNFSSFVRQLNTYVGTSAGNCSSFAEQasvgfrkvDADKWEFANEGFRQGQ 168
                   9**********************************************************8777777666555556666654499************* PP

                   XXXXXXXXXXXX CS
  HSF_DNA-bind  91 kellekikrkks 102
                   ++ll++i+r+ks
   Lus10014369 169 RHLLRNIQRRKS 180
                   **********98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004155.7E-4968178IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467855.98E-3068178IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.7E-3369178IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000561.1E-117295IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004476.7E-2772178IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-11110122IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-11123135IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 447 aa     Download sequence    Send to blast
MNPEEEYYSE SPDASSIPVC SVMEEMPIPA SPLMAFEDFS QAFEFKAEPL IPPVAIIPQP  60
LSILQEIPVP PFLSKTFDLV DDQGLDPVIS WGGRGESFVV WDPVEFSRTV LPRNFKHNNF  120
SSFVRQLNTY VGTSAGNCSS FAEQASVGFR KVDADKWEFA NEGFRQGQRH LLRNIQRRKS  180
PQMSTNVVES GLETEVERLR KERSTMMQEV VELQRQQRGS VKHIETVNKR IQDAEQRQKQ  240
MLSFLAKLFH NRAFLDRLKQ SKEEKVLGAP SSRTRKKFIR HNQPESYTTQ GQIVQQPPEY  300
ALEGIVEEGF PFEMDTFVSD ELIIPQEQIE EKATTLQSEE LHCKGKHVMD PQQQELGPEY  360
LVSFPDDFGM QDFPAASSGF ETELWNDVVR YDVPEFGGVA GGFSDIWDLG STQGAGSSGV  420
DKQLADESLL TEPPTDNSSG LNNLDA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A5e-186917817120Heat shock factor protein 1
5hdg_A4e-18691787110Heat shock factor protein 1
5hdn_A4e-18691787110Heat shock factor protein 1
5hdn_B4e-18691787110Heat shock factor protein 1
5hdn_C4e-18691787110Heat shock factor protein 1
5hdn_D4e-18691787110Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress response. Activated by DREB2A under heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10014369
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021619963.11e-129heat stress transcription factor A-3
SwissprotQ8GYY11e-100HSFA3_ARATH; Heat stress transcription factor A-3
TrEMBLA0A1R3HCY61e-124A0A1R3HCY6_9ROSI; Heat shock factor (HSF)-type, DNA-binding protein
STRINGLus100143690.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF87823038
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03720.11e-102heat shock transcription factor A3
Publications ? help Back to Top
  1. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  4. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  5. Song C,Chung WS,Lim CO
    Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
    Mol. Cells, 2016. 39(6): p. 477-83
    [PMID:27109422]
  6. Kim GD,Cho YH,Lee BH,Yoo SD
    STABILIZED1 Modulates Pre-mRNA Splicing for Thermotolerance.
    Plant Physiol., 2017. 173(4): p. 2370-2382
    [PMID:28223317]
  7. Song C,Lee J,Kim T,Hong JC,Lim CO
    VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis.
    Planta, 2018. 247(6): p. 1439-1448
    [PMID:29536220]