PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10018414
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family MYB_related
Protein Properties Length: 503aa    MW: 55303.4 Da    PI: 7.9119
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10018414genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding26.31.7e-08440481346
                      SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      +++ +E+ l  +  ++ G + W++Ia +++ gRt+ ++  +w++
      Lus10018414 440 KFSDDEESLVTRMYNLVGER-WHLIAGRIP-GRTAQDVEKYWNS 481
                      89*****************9.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF017334.5E-26136413IPR002259Equilibrative nucleoside transporter
SuperFamilySSF1034732.62E-6196406IPR020846Major facilitator superfamily domain
PROSITE profilePS5129410.934433487IPR017930Myb domain
SMARTSM007173.1E-7437485IPR001005SANT/Myb domain
SuperFamilySSF466894.4E-7439482IPR009057Homeodomain-like
PfamPF002494.9E-7440481IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.2E-10440481IPR009057Homeodomain-like
CDDcd001671.15E-6440480No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006810Biological Processtransport
GO:0016021Cellular Componentintegral component of membrane
GO:0003677Molecular FunctionDNA binding
GO:0005337Molecular Functionnucleoside transmembrane transporter activity
Sequence ? help Back to Top
Protein Sequence    Length: 503 aa     Download sequence    Send to blast
MSQIVDGGRV VVDGGEVDPT TRLEGKYKAV IVCWILGFGG IIAWNAMVTI EDYYYTLFPE  60
YHPSRVLTMI YQPFALGAMA ICTYYESKMD TRKRNIAGYS MIFVSTSMLL VLDLATSGSG  120
GIGPFIGICG VVGAFGVSDV LVQGGVVGEL SFMCPEFIQS YYGGMAACGA MTSGLRLVTK  180
ATFENVDHGL RKGVLMFLGI SISLEFLCIL LYAFYLPKLP IINYYRTKAS KEGSKTVSAD  240
LKAAGIQVPT TQGDDVTPPA RLSTKELLIH NVDYFLDLYF TYTLTLSIFP GFISENTGTH  300
GMGTWYILVL IAMYNAWDLI GRYVPMVECI KLKSRKGLMI ATVSRFLLVP AFYFAAKYAD  360
KGWMIALTSF LGLTTGYLTV CVMTLAPKGY KGPEQNALGN LLVLFLLAGI FTGVEKGTNS  420
LSSSLKIMDG ELRSPQKEVK FSDDEESLVT RMYNLVGERW HLIAGRIPGR TAQDVEKYWN  480
SRRSASEEHT LTRSCNSFYT AI*
Functional Description ? help Back to Top
Source Description
UniProtNucleoside transporter that functions as a pyrimidine nucleoside carrier in all organs. Has high affinity for adenosine and uridine when expressed in a heterologous system (yeast). Mediates proton-dependent adenosine or uridine transport in Xenopus oocytes. {ECO:0000269|PubMed:12810710, ECO:0000269|PubMed:15228386, ECO:0000269|PubMed:17253988, ECO:0000269|PubMed:22372734}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10018414
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By nitrogen deficiency and 5-fluorouracil plus methotrexate. {ECO:0000269|PubMed:12810710}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021902220.10.0equilibrative nucleotide transporter 3-like
RefseqXP_021902221.10.0equilibrative nucleotide transporter 3-like
RefseqXP_021902222.10.0equilibrative nucleotide transporter 3-like
SwissprotQ9M0Y30.0ENT3_ARATH; Equilibrative nucleotide transporter 3
TrEMBLA0A314KLL10.0A0A314KLL1_NICAT; Equilibrative nucleotide transporter 3
STRINGLus100184140.0(Linum usitatissimum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G46410.11e-16MYB_related family protein
Publications ? help Back to Top
  1. Möhlmann T,Mezher Z,Schwerdtfeger G,Neuhaus HE
    Characterisation of a concentrative type of adenosine transporter from Arabidopsis thaliana (ENT1,At).
    FEBS Lett., 2001. 509(3): p. 370-4
    [PMID:11749958]
  2. Li G,Liu K,Baldwin SA,Wang D
    Equilibrative nucleoside transporters of Arabidopsis thaliana. cDNA cloning, expression pattern, and analysis of transport activities.
    J. Biol. Chem., 2003. 278(37): p. 35732-42
    [PMID:12810710]
  3. Wormit A,Traub M,Flörchinger M,Neuhaus HE,Möhlmann T
    Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family.
    Biochem. J., 2004. 383(Pt 1): p. 19-26
    [PMID:15228386]
  4. Chen KL, et al.
    Identification of AtENT3 as the main transporter for uridine uptake in Arabidopsis roots.
    Cell Res., 2006. 16(4): p. 377-88
    [PMID:16617333]
  5. Pavet V,Quintero C,Cecchini NM,Rosa AL,Alvarez ME
    Arabidopsis displays centromeric DNA hypomethylation and cytological alterations of heterochromatin upon attack by pseudomonas syringae.
    Mol. Plant Microbe Interact., 2006. 19(6): p. 577-87
    [PMID:16776291]
  6. Traub M, et al.
    The fluorouridine insensitive 1 (fur1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), and thus represents an important pyrimidine nucleoside uptake system in Arabidopsis thaliana.
    Plant J., 2007. 49(5): p. 855-64
    [PMID:17253988]
  7. Cornelius S, et al.
    Nucleoside transport across the plasma membrane mediated by equilibrative nucleoside transporter 3 influences metabolism of Arabidopsis seedlings.
    Plant Biol (Stuttg), 2012. 14(5): p. 696-705
    [PMID:22372734]
  8. Daumann M,Fischer M,Niopek-Witz S,Girke C,Möhlmann T
    Apoplastic Nucleoside Accumulation in Arabidopsis Leads to Reduced Photosynthetic Performance and Increased Susceptibility Against Botrytis cinerea.
    Front Plant Sci, 2015. 6: p. 1158
    [PMID:26779190]