PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lus10018756

Organism

Linum usitatissimum

Taxonomic ID

4006

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum

Family

ERF

Protein Properties

Length: 849aa MW: 94588.7 Da PI: 7.8198

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Lus10018756	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	66.4	5.5e-21	745	795	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++y+GVr++ +grW+AeIrdp + r+r++lg+++taeeAa+a+++a+ +++g Lus10018756 745 TKYRGVRRRQ-WGRWAAEIRDPLN---RRRIWLGTYDTAEEAARAYDEAAIRIKG 795 69***887.******854...5*********************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.710.10	5.2E-16	39	179	No hit	No description
SuperFamily	SSF54695	6.67E-14	55	180	IPR011333	SKP1/BTB/POZ domain
Pfam	PF00651	1.6E-11	55	179	IPR000210	BTB/POZ domain
PROSITE profile	PS50097	17.645	58	132	IPR000210	BTB/POZ domain
SMART	SM00225	5.0E-13	58	183	IPR000210	BTB/POZ domain
SuperFamily	SSF48403	7.75E-17	259	369	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	1800	262	290	IPR002110	Ankyrin repeat
Gene3D	G3DSA:1.25.40.20	8.2E-18	266	403	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	4.46E-15	267	366	No hit	No description
PROSITE profile	PS50297	16.122	291	366	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	210	291	321	IPR002110	Ankyrin repeat
Pfam	PF13637	7.7E-5	294	339	No hit	No description
PROSITE profile	PS50088	9.11	325	357	IPR002110	Ankyrin repeat
SMART	SM00248	0.43	325	354	IPR002110	Ankyrin repeat
Pfam	PF12313	1.2E-78	367	584	IPR021094	NPR1/NIM1-like, C-terminal
CDD	cd00018	5.44E-31	745	801	No hit	No description
Pfam	PF00847	8.2E-15	745	795	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.8E-28	746	803	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.459	746	803	IPR001471	AP2/ERF domain
SMART	SM00380	8.1E-33	746	809	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.18E-20	746	802	IPR016177	DNA-binding domain
PRINTS	PR00367	4.0E-10	747	758	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-10	769	785	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001666	Biological Process	response to hypoxia
GO:0008219	Biological Process	cell death
GO:0009408	Biological Process	response to heat
GO:0009611	Biological Process	response to wounding
GO:0009625	Biological Process	response to insect
GO:0009682	Biological Process	induced systemic resistance
GO:0009862	Biological Process	systemic acquired resistance, salicylic acid mediated signaling pathway
GO:0010112	Biological Process	regulation of systemic acquired resistance
GO:0031348	Biological Process	negative regulation of defense response
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0050832	Biological Process	defense response to fungus
GO:2000022	Biological Process	regulation of jasmonic acid mediated signaling pathway
GO:2000031	Biological Process	regulation of salicylic acid mediated signaling pathway
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 849 aa Download sequence Send to blast
MDYRFGICDS NDIISNGSSS CCVEPPSTSQ PEIASLHRLS QNLDSMIETS SPEFDFFADA 60 KIAVRGREVA VHRCILSSRS PYFRNVLSSS SSEKKCGEVF ELKELAKDYD VGFESLAAVL 120 GYLYSGRVRA SPPAGVCVCV DDDCPHLACR PALDFLVEVL YASYIFQVPE WVALYQKKLV 180 DVLDKVSTDD ALVILSVANL CDKSCELLLA RCIDMMVKSN VDIVTLDKAL PHHIVKQITD 240 ARWMLNSYKT HDEKQEIHPD NKHVKRIHRA LDSDDVELVR MLLKEGHTNL DDAEALHYAV 300 AYCDSKTTME VLDLGLADVN RTNSRGYTVL HVAAMRKEPK IIVSLLTKGA RPCALTSDGR 360 KALQIAKRLT RAADYHKYLT TEEGGNNNNS KASSKERLCI EILEQAERRS PLLGEASVSL 420 ALAGDDLRRK LLYLENRVGL AKLLFPMEAK VVMDITQQDG TSDEFPLGNM IQSNNSADAA 480 QRRTVDLNEA PFRIKEELLN RMRALSRAVE VGKRFFPRCS DVLNKIMDDD NELTQLACLG 540 NGTPEERQRK RKRYLELQQL LGKAFNADKE EFDRTSAISS SSASKSKSVD GILPPPAKRS 600 ATETVPISIS LLFRLLLLHR TPQKISVMST NTSTPSPTPA DVKYTEHRTV TSMIVKLHDP 660 TAKKIVRISV TDGDATDSSG DENEHGGRGR TAEESVRLRR HQHQRVKKHI QEIIIRDRNA 720 MTDELPPCKE SSGEQEIRDC PLIGTKYRGV RRRQWGRWAA EIRDPLNRRR IWLGTYDTAE 780 EAARAYDEAA IRIKGAGAFT NLMKVKPPAA NEKKRFVASP PESAVSGCNS GEESRSCGKN 840 MPQVGVES*

Sequence ? help Back to Top

Protein Sequence Length: 849 aa Download sequence Send to blast

MDYRFGICDS NDIISNGSSS CCVEPPSTSQ PEIASLHRLS QNLDSMIETS SPEFDFFADA  60
KIAVRGREVA VHRCILSSRS PYFRNVLSSS SSEKKCGEVF ELKELAKDYD VGFESLAAVL  120
GYLYSGRVRA SPPAGVCVCV DDDCPHLACR PALDFLVEVL YASYIFQVPE WVALYQKKLV  180
DVLDKVSTDD ALVILSVANL CDKSCELLLA RCIDMMVKSN VDIVTLDKAL PHHIVKQITD  240
ARWMLNSYKT HDEKQEIHPD NKHVKRIHRA LDSDDVELVR MLLKEGHTNL DDAEALHYAV  300
AYCDSKTTME VLDLGLADVN RTNSRGYTVL HVAAMRKEPK IIVSLLTKGA RPCALTSDGR  360
KALQIAKRLT RAADYHKYLT TEEGGNNNNS KASSKERLCI EILEQAERRS PLLGEASVSL  420
ALAGDDLRRK LLYLENRVGL AKLLFPMEAK VVMDITQQDG TSDEFPLGNM IQSNNSADAA  480
QRRTVDLNEA PFRIKEELLN RMRALSRAVE VGKRFFPRCS DVLNKIMDDD NELTQLACLG  540
NGTPEERQRK RKRYLELQQL LGKAFNADKE EFDRTSAISS SSASKSKSVD GILPPPAKRS  600
ATETVPISIS LLFRLLLLHR TPQKISVMST NTSTPSPTPA DVKYTEHRTV TSMIVKLHDP  660
TAKKIVRISV TDGDATDSSG DENEHGGRGR TAEESVRLRR HQHQRVKKHI QEIIIRDRNA  720
MTDELPPCKE SSGEQEIRDC PLIGTKYRGV RRRQWGRWAA EIRDPLNRRR IWLGTYDTAE  780
EAARAYDEAA IRIKGAGAFT NLMKVKPPAA NEKKRFVASP PESAVSGCNS GEESRSCGKN  840
MPQVGVES*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	3e-17	746	802	14	71	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Key positive factor of disease resistance. Plays an essential role in benzothiadiazole (BTH)-induced resistance to the blast fungus disease caused by Magnaporthe oryzae (PubMed:20924648). Involved in defense response against the bacterial blight disease caused by Xanthomonas oryzae pv. oryzae (Xoo). Over-expression of NPR1/NH1 confers disease resistance to Xoo, but also enhances herbivore susceptibility (PubMed:17309686). Functions as a transcriptional coactivator of TGA2.1 and LG2 in vitro (PubMed:22353606). Involved in defense response against herbivore. Plants silencing NPR1/NH1 have increased herbivore-induced trypsin proteinase inhibitors and volatiles, which reduces the performance of the striped stem borer (SSB) Chilo suppressalis (PubMed:22694163). {ECO:0000269\|PubMed:17309686, ECO:0000269\|PubMed:20924648, ECO:0000269\|PubMed:22353606, ECO:0000269\|PubMed:22694163}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Lus10018756

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By mechanical wounding, treatment with jasmonic acid (JA), salicylic acid (SA) and benzothiadiazole (BTH), and in response to infestation by the rice striped stem borer Chilo suppressalis and rice leaf folder Cnaphalocrocis medinalis. {ECO:0000269\|PubMed:22694163}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021597891.1	0.0	BTB/POZ domain and ankyrin repeat-containing protein NPR1 isoform X1
Swissprot	Q9FDY4	0.0	NPR1_ORYSJ; BTB/POZ domain and ankyrin repeat-containing protein NPR1
TrEMBL	A0A2C9UAL7	0.0	A0A2C9UAL7_MANES; Uncharacterized protein
STRING	Lus10018756	0.0	(Linum usitatissimum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G27950.1	1e-21	cytokinin response factor 4

Link Out ? help Back to Top
Phytozome	Lus10018756

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Chern M,Fitzgerald HA,Canlas PE,Navarre DA,Ronald PC Overexpression of a rice NPR1 homolog leads to constitutive activation of defense response and hypersensitivity to light. Mol. Plant Microbe Interact., 2005. 18(6): p. 511-20 [PMID:15986920] Chern M,Canlas PE,Fitzgerald HA,Ronald PC Rice NRR, a negative regulator of disease resistance, interacts with Arabidopsis NPR1 and rice NH1. Plant J., 2005. 43(5): p. 623-35 [PMID:16115061] Liu XQ, et al. OsWRKY03, a rice transcriptional activator that functions in defense signaling pathway upstream of OsNPR1. Cell Res., 2005. 15(8): p. 593-603 [PMID:16117849] Yuan Y, et al. Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility. Plant Biotechnol. J., 2007. 5(2): p. 313-24 [PMID:17309686] Yuan B,Shen X,Li X,Xu C,Wang S Mitogen-activated protein kinase OsMPK6 negatively regulates rice disease resistance to bacterial pathogens. Planta, 2007. 226(4): p. 953-60 [PMID:17541629] Zhao N, et al. Biosynthesis and emission of insect-induced methyl salicylate and methyl benzoate from rice. Plant Physiol. Biochem., 2010. 48(4): p. 279-87 [PMID:20199866] Jiang CJ, et al. Abscisic acid interacts antagonistically with salicylic acid signaling pathway in rice-Magnaporthe grisea interaction. Mol. Plant Microbe Interact., 2010. 23(6): p. 791-8 [PMID:20459318] Bai W, et al. Enhanced disease resistance and hypersensitivity to BTH by introduction of an NH1/OsNPR1 paralog. Plant Biotechnol. J., 2011. 9(2): p. 205-15 [PMID:20561248] Bart RS,Chern M,Vega-Sánchez ME,Canlas P,Ronald PC Rice Snl6, a cinnamoyl-CoA reductase-like gene family member, is required for NH1-mediated immunity to Xanthomonas oryzae pv. oryzae. PLoS Genet., 2010. 6(9): p. e1001123 [PMID:20862311] Sugano S, et al. Role of OsNPR1 in rice defense program as revealed by genome-wide expression analysis. Plant Mol. Biol., 2010. 74(6): p. 549-62 [PMID:20924648] Babu R, et al. Isolation, fine mapping and expression profiling of a lesion mimic genotype, spl(NF4050-8) that confers blast resistance in rice. Theor. Appl. Genet., 2011. 122(4): p. 831-54 [PMID:21132425] Delteil A, et al. Building a mutant resource for the study of disease resistance in rice reveals the pivotal role of several genes involved in defence. Mol. Plant Pathol., 2012. 13(1): p. 72-82 [PMID:21726398] Peng DH,Qiu DW,Ruan LF,Zhou CF,Sun M Protein elicitor PemG1 from Magnaporthe grisea induces systemic acquired resistance (SAR) in plants. Mol. Plant Microbe Interact., 2011. 24(10): p. 1239-46 [PMID:21770770] Campos-Soriano L,García-Martínez J,San Segundo B The arbuscular mycorrhizal symbiosis promotes the systemic induction of regulatory defence-related genes in rice leaves and confers resistance to pathogen infection. Mol. Plant Pathol., 2012. 13(6): p. 579-92 [PMID:22212404] Chern M, et al. A rice transient assay system identifies a novel domain in NRR required for interaction with NH1/OsNPR1 and inhibition of NH1-mediated transcriptional activation. Plant Methods, 2012. 8(1): p. 6 [PMID:22353606] Ge H, et al. The rice diacylglycerol kinase family: functional analysis using transient RNA interference. Front Plant Sci, 2012. 3: p. 60 [PMID:22639654] Li R,Afsheen S,Xin Z,Han X,Lou Y OsNPR1 negatively regulates herbivore-induced JA and ethylene signaling and plant resistance to a chewing herbivore in rice. Physiol Plant, 2013. 147(3): p. 340-51 [PMID:22694163] Sun L, et al. Functions of rice NAC transcriptional factors, ONAC122 and ONAC131, in defense responses against Magnaporthe grisea. Plant Mol. Biol., 2013. 81(1-2): p. 41-56 [PMID:23103994] Jiang CJ, et al. Cytokinins act synergistically with salicylic acid to activate defense gene expression in rice. Mol. Plant Microbe Interact., 2013. 26(3): p. 287-96 [PMID:23234404] Sharma R,De Vleesschauwer D,Sharma MK,Ronald PC Recent advances in dissecting stress-regulatory crosstalk in rice. Mol Plant, 2013. 6(2): p. 250-60 [PMID:23292878] Mou S, et al. Functional analysis and expressional characterization of rice ankyrin repeat-containing protein, OsPIANK1, in basal defense against Magnaporthe oryzae attack. PLoS ONE, 2013. 8(3): p. e59699 [PMID:23555750] Chern M,Bai W,Chen X,Canlas PE,Ronald PC Reduced expression of glycolate oxidase leads to enhanced disease resistance in rice. PeerJ, 2013. 1: p. e28 [PMID:23638363] Nakayama A, et al. Genome-wide identification of WRKY45-regulated genes that mediate benzothiadiazole-induced defense responses in rice. BMC Plant Biol., 2013. 13: p. 150 [PMID:24093634] Chern M, et al. Interaction specificity and coexpression of rice NPR1 homologs 1 and 3 (NH1 and NH3), TGA transcription factors and Negative Regulator of Resistance (NRR) proteins. BMC Genomics, 2014. 15: p. 461 [PMID:24919709] Takatsuji H Development of disease-resistant rice using regulatory components of induced disease resistance. Front Plant Sci, 2014. 5: p. 630 [PMID:25431577] Mou S, et al. Over-Expression of Rice CBS Domain Containing Protein, OsCBSX3, Confers Rice Resistance to Magnaporthe oryzae Inoculation. Int J Mol Sci, 2015. 16(7): p. 15903-17 [PMID:26184180] Li SB,Xu SR,Zhang RN,Liu Y,Zhou RC The Antibiosis Action and Rice-Induced Resistance, Mediated by a Lipopeptide from Bacillus amyloliquefaciens B014, in Controlling Rice Disease Caused by Xanthomonas oryzae pv. oryzae. J. Microbiol. Biotechnol., 2016. 26(4): p. 748-56 [PMID:26718470] Harkenrider M, et al. Overexpression of Rice Wall-Associated Kinase 25 (OsWAK25) Alters Resistance to Bacterial and Fungal Pathogens. PLoS ONE, 2016. 11(1): p. e0147310 [PMID:26795719] Fred AK,Kiswara G,Yi G,Kim KM Screening Rice Cultivars for Resistance to Bacterial Leaf Blight. J. Microbiol. Biotechnol., 2016. 26(5): p. 938-45 [PMID:26869604] Kadotani N,Akagi A,Takatsuji H,Miwa T,Igarashi D Exogenous proteinogenic amino acids induce systemic resistance in rice. BMC Plant Biol., 2016. 16: p. 60 [PMID:26940322] Chern M, et al. A Genetic Screen Identifies a Requirement for Cysteine-Rich-Receptor-Like Kinases in Rice NH1 (OsNPR1)-Mediated Immunity. PLoS Genet., 2016. 12(5): p. e1006049 [PMID:27176732] Li X, et al. The Systemic Acquired Resistance Regulator OsNPR1 Attenuates Growth by Repressing Auxin Signaling through Promoting IAA-Amido Synthase Expression. Plant Physiol., 2016. 172(1): p. 546-58 [PMID:27378815] Chern M, et al. Correction: A Genetic Screen Identifies a Requirement for Cysteine-Rich-Receptor-Like Kinases in Rice NH1 (OsNPR1)-Mediated Immunity. PLoS Genet., 2016. 12(7): p. e1006182 [PMID:27385201]