PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10031321
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family HD-ZIP
Protein Properties Length: 717aa    MW: 78657.7 Da    PI: 6.3955
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10031321genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox62.85e-203994156
                 TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
     Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                 ++k +++t  q++ Le++F+++++p++++r  L+++lgL+ rq+k+WFqNrR+++k
  Lus10031321 39 KKKYHRHTVAQIQKLEAMFKECPHPDEKQRLYLSRELGLSPRQIKFWFQNRRTQMK 94
                 79999************************************************998 PP
2START171.36.4e-542314532206
                  HHHHHHHHHHHHHHHC-TT-EEEE.....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEE CS
        START   2 laeeaaqelvkkalaeepgWvkss.....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetlev 84 
                  +a  a +el+++   +ep+W+ks      + +n + + ++f++ +        ++ea+r+sgvv+m+   lv  ++d + +W e ++     a+t+ev
  Lus10031321 231 VAGNAVDELLRLLRTDEPMWMKSLdgggrDVLNLESYQKIFPKPNDhlknpnVRIEASRDSGVVIMNGLALVDMFMDAN-KWMELFPtivsMAKTIEV 327
                  677899******************99999889999999999776658999999**************************.***999999999****** PP

                  ECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SS CS
        START  85 issg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgr 175
                  +++g      g lql++ elq+lsplvp R+f+++Ry++q ++g+w++v vS d +q+ ++     R+ +lpSg+lie+++ng+skvtwvehv+ ++r
  Lus10031321 328 LTPGmigaynGCLQLIYEELQVLSPLVPtREFYILRYCQQIEQGVWAVVNVSYDIPQFASQ----FRSYRLPSGCLIEDMPNGYSKVTWVEHVEIEDR 421
                  **********************************************************986....9******************************** PP

                  XX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
        START 176 lp.hwllrslvksglaegaktwvatlqrqcek 206
                   p h l+r l+ sg+a+ga +w++tlqr ce+
  Lus10031321 422 APiHRLYRDLIYSGMAFGAERWLSTLQRMCER 453
                  ******************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.25E-202596IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.609.0E-222698IPR009057Homeodomain-like
PROSITE profilePS5007117.4433696IPR001356Homeobox domain
SMARTSM003898.1E-2038100IPR001356Homeobox domain
PfamPF000461.3E-173994IPR001356Homeobox domain
CDDcd000861.50E-193997No hitNo description
PROSITE patternPS0002707194IPR017970Homeobox, conserved site
PROSITE profilePS5084851.238221456IPR002913START domain
SuperFamilySSF559611.53E-37223454No hitNo description
CDDcd088753.28E-115225452No hitNo description
SMARTSM002342.2E-47230453IPR002913START domain
PfamPF018521.6E-46231453IPR002913START domain
Gene3DG3DSA:3.30.530.202.7E-7296423IPR023393START-like domain
SuperFamilySSF559612.2E-22474707No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 717 aa     Download sequence    Send to blast
MEYSNAGGGG ALGGTLGGGG GGAGSGDHDS SSDVQMKKKK KYHRHTVAQI QKLEAMFKEC  60
PHPDEKQRLY LSRELGLSPR QIKFWFQNRR TQMKAQHERA DNCALRAEND KIRCENIAIR  120
EALRNVICPS CGGPPVNEDS YFDEHKLRIE NAQLKEELDR VSSIAGKYIG RPISHLPPVQ  180
PIPVSSLDLS MGNFGGHPLD LDVDLLPQQQ PNLPFQPLGI SSMDKSMMMD VAGNAVDELL  240
RLLRTDEPMW MKSLDGGGRD VLNLESYQKI FPKPNDHLKN PNVRIEASRD SGVVIMNGLA  300
LVDMFMDANK WMELFPTIVS MAKTIEVLTP GMIGAYNGCL QLIYEELQVL SPLVPTREFY  360
ILRYCQQIEQ GVWAVVNVSY DIPQFASQFR SYRLPSGCLI EDMPNGYSKV TWVEHVEIED  420
RAPIHRLYRD LIYSGMAFGA ERWLSTLQRM CERFACLMVS NASTRDLGGV IPSPDGKRSM  480
MKLAQRMVNS FCSSISTSTS HQWTTLSGLD EVGVRVTLRK STDPGQPNGV VLSAATTFWL  540
PVSPQNVFNF FKDEKTRSQW DVLSSGNGVQ EVAHIANGSH PGNCISVLRA FNTSQNNMLI  600
LQESCIDSSG SLVVYCPVEL QAINIAMSGE DPSCIPLLPS GFTICSDGSF GQPSSSADGA  660
STSGKSTGSL ITVAFQILVS SLPSAKLNME SVTTVNNLIG TTVQQIKAAL NCPQSS*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10031321
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017973835.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2P5B2950.0A0A2P5B295_TREOI; Octamer-binding transcription factor
STRINGLus100313210.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]