PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10031892
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family HD-ZIP
Protein Properties Length: 617aa    MW: 67909.2 Da    PI: 6.9074
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10031892genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox63.14.1e-203489156
                 TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
     Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                 ++k +++t  q++ Le++F+++++p++++r  L+++lgL+ rq+k+WFqNrR+++k
  Lus10031892 34 KKKYHRHTVAQIQKLEAMFKECPHPDEKQRLYLSRELGLSPRQIKFWFQNRRTQMK 89
                 79999************************************************998 PP
2START159.62.4e-5018235341206
                  S.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEE CS
        START  41 kvdsgealrasgvvdmvlallveellddkeqWdetla....kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivd 127
                  +  ++ea+r+sgvv+m+   lv  ++d + +W e ++     a+t+ev+++g      g lqlm+ elq+lsplvp R+f+++Ry++q ++g+w++v 
  Lus10031892 182 N-VRIEASRDSGVVIMNGLALVDMFMDAN-KWMELFPtivsMAKTIEVLTPGmisaynGCLQLMYEELQVLSPLVPtREFYILRYCQQIEQGVWAVVN 277
                  3.489************************.***999999999******************************************************** PP

                  EEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
        START 128 vSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                  vS d +q+ ++     R+ +lpSg+lie+++ng+skvtwvehv+ ++r p h l+r l+ sg+a+ga +w++tlqr ce+
  Lus10031892 278 VSYDIPQFASQ----FRSYRLPSGCLIEDMPNGYSKVTWVEHVEIEDRAPiHRLYRDLIYSGMAFGAERWLSTLQRMCER 353
                  ********986....9**************************************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.04E-202091IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.607.3E-222193IPR009057Homeodomain-like
PROSITE profilePS5007117.4433191IPR001356Homeobox domain
SMARTSM003898.1E-203395IPR001356Homeobox domain
CDDcd000862.34E-193492No hitNo description
PfamPF000461.0E-173489IPR001356Homeobox domain
PROSITE patternPS0002706689IPR017970Homeobox, conserved site
SMARTSM002341.9E-39139353IPR002913START domain
CDDcd088751.09E-103153352No hitNo description
PfamPF018522.9E-43183353IPR002913START domain
SuperFamilySSF559611.53E-33183354No hitNo description
PROSITE profilePS5084839.942186356IPR002913START domain
Gene3DG3DSA:3.30.530.203.9E-7200323IPR023393START-like domain
SuperFamilySSF559611.21E-22374607No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 617 aa     Download sequence    Send to blast
MEYSNAGGGA LGGGGGGAGS GDHDSSSDVQ MKKKKKYHRH TVAQIQKLEA MFKECPHPDE  60
KQRLYLSREL GLSPRQIKFW FQNRRTQMKA QHERADNCAL RAENDKIRCE NIAIREALRN  120
VICPSCGGPP VNEDSYFDEH KLRIENAQLK EESLDGGGRD VLNLETYQKL FPKPNDHLKN  180
PNVRIEASRD SGVVIMNGLA LVDMFMDANK WMELFPTIVS MAKTIEVLTP GMISAYNGCL  240
QLMYEELQVL SPLVPTREFY ILRYCQQIEQ GVWAVVNVSY DIPQFASQFR SYRLPSGCLI  300
EDMPNGYSKV TWVEHVEIED RAPIHRLYRD LIYSGMAFGA ERWLSTLQRM CERFACLMVS  360
NTSTRDLGGV IPSPDGKRSM MKLAQRMVNS FCSSISTSNS HQWTTLSGLD EVGVRVTLRK  420
STNPGQPNGV VLSAATTFWL PVSPQNVFNF FKDEKTRSQW DVLSSGNGVQ EVAHIANGSH  480
PGNCISVLRA FNTSQNNMLI LQESCIDSSG SLVVYCPVEL QAINIAMSGE DPSCIPLLPS  540
GFTICSDGSL GQPSSSADGA STSGKSTGSL ITVAFQILVS SLPSAKLNME SVTTVNNLIG  600
TTVQQIKAAL NCPQSS*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10031892
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021687701.10.0homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLB9N3B20.0B9N3B2_POPTR; Uncharacterized protein
STRINGLus100318920.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]