PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10037448
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family ERF
Protein Properties Length: 379aa    MW: 41119.4 Da    PI: 4.4915
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10037448genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP260.92.8e-19118167255
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  +y+G+r+++ +g+W+AeIrdp++     r++lg+f taeeAa+a++a +++++g
  Lus10037448 118 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDAEARRIRG 167
                  69*******.**********954...4************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003801.3E-35118181IPR001471AP2/ERF domain
PROSITE profilePS5103224.092118175IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.5E-32118176IPR001471AP2/ERF domain
SuperFamilySSF541713.07E-22118176IPR016177DNA-binding domain
CDDcd000189.99E-33118177No hitNo description
PRINTSPR003671.1E-11119130IPR001471AP2/ERF domain
PfamPF008478.5E-12119167IPR001471AP2/ERF domain
PRINTSPR003671.1E-11141157IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 379 aa     Download sequence    Send to blast
MCGGAIISGF IPPTSVAART SSRRLTSDFL WPDLKSKSVS KPYSKPAVVV DLDDDFEADF  60
QEFKDDSDVD VDDVDDVLAD VKPFAFSAPP PPARSAAVNS VEFSGQAEKS AKRKRKNQYR  120
GIRQRPWGKW AAEIRDPRKG VRVWLGTFNT AEEAARAYDA EARRIRGKKA KVNFPDDAAT  180
PRAMPAKRSG KAKAQKPSSA APKIPNLDNS ECFVEEKPSA NQLGMMVDPT LASNDGVNNM  240
SAVPSDAAVY FSSDQGSNSF DFSDFGWTEQ VPKTPEISSV FLPAGPEFSE SGFVDEDANH  300
SKKQKCSNSG NTNDVSPAAE EELFGFDKLL QMPYMDGGWE ASLDNLLNGD STQDCGNSSL  360
EDLWSFDNLS NMVGEGGY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A2e-201171771374Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269|PubMed:22020282, ECO:0000269|PubMed:22530619}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10037448
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269|PubMed:22020282}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021628280.11e-143ethylene-responsive transcription factor RAP2-12-like
RefseqXP_021628281.11e-143ethylene-responsive transcription factor RAP2-12-like
SwissprotQ9SSA83e-77RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBLA0A251K7811e-141A0A251K781_MANES; Uncharacterized protein
STRINGLus100374480.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF48083252
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G53910.31e-61related to AP2 12
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kosmacz M, et al.
    The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration.
    Plant Cell Environ., 2015. 38(6): p. 1094-103
    [PMID:25438831]
  3. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  4. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  5. Gonzali S, et al.
    Universal stress protein HRU1 mediates ROS homeostasis under anoxia.
    Nat Plants, 2015. 1: p. 15151
    [PMID:27251529]
  6. Paul MV, et al.
    Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia.
    Plant Physiol., 2016. 172(1): p. 141-53
    [PMID:27372243]
  7. Shahzad Z, et al.
    A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics.
    Cell, 2016. 167(1): p. 87-98.e14
    [PMID:27641502]
  8. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  9. Giuntoli B,Licausi F,van Veen H,Perata P
    Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants.
    Front Plant Sci, 2017. 8: p. 591
    [PMID:28487707]
  10. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]
  11. Eysholdt-Derzsó E,Sauter M
    Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling.
    Plant Physiol., 2017. 175(1): p. 412-423
    [PMID:28698356]
  12. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]