PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000121984
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family AP2
Protein Properties Length: 509aa    MW: 55514.8 Da    PI: 9.0477
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000121984genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP236.71e-11130186155
            AP2   1 sgykGVrwdkkrgrWvAeIrd.pseng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                    s y+GV++++++gr++A+++d  +     ++ k  + g ++ +e+Aa+a++ a++k++g
  MDP0000121984 130 SIYRGVTRHRWTGRYEAHLWDnSCR-RegQSrKGRQ-GGYDKEEKAARAYDLAALKYWG 186
                    57*******************5444.2455536655.779999**************98 PP
2AP247.35.3e-15229280155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  MDP0000121984 229 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDIAAIKFRG 280
                    57****************988532...5************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008473.6E-9130186IPR001471AP2/ERF domain
SuperFamilySSF541717.19E-15130195IPR016177DNA-binding domain
CDDcd000181.04E-18130195No hitNo description
SMARTSM003807.2E-23131200IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.7E-12131194IPR001471AP2/ERF domain
PROSITE profilePS5103217.477131194IPR001471AP2/ERF domain
PRINTSPR003672.1E-6132143IPR001471AP2/ERF domain
PfamPF008476.6E-10229280IPR001471AP2/ERF domain
SuperFamilySSF541717.19E-18229290IPR016177DNA-binding domain
CDDcd000181.51E-24229290No hitNo description
SMARTSM003801.5E-33230294IPR001471AP2/ERF domain
PROSITE profilePS5103219.045230288IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.3E-18230289IPR001471AP2/ERF domain
PRINTSPR003672.1E-6270290IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009845Biological Processseed germination
GO:0040019Biological Processpositive regulation of embryonic development
GO:0048364Biological Processroot development
GO:0060772Biological Processleaf phyllotactic patterning
GO:0060774Biological Processauxin mediated signaling pathway involved in phyllotactic patterning
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 509 aa     Download sequence    Send to blast
TVAGHHHQGA SPTSATDLSI FSSGINGPKL EDFLGGCTPA ANTVTPTSLP QFATADHHHQ  60
ITPLALSQNE IYDSELKTIA ASFLRGFSTT ATTTTTAATL QTTKLQNHHP LASSDPTPKK  120
PADTFGQRTS IYRGVTRHRW TGRYEAHLWD NSCRREGQSR KGRQGGYDKE EKAARAYDLA  180
ALKYWGPTTT TNFPVINYEK ELSEMKNMTR QEFVASLRRK SSGFSRGASI YRGVTRHHQH  240
GRWQARIGRV AGNKDLYLGT FSTQEEAAEA YDIAAIKFRG LNAVTNFDMS RYDVKSIASS  300
NLPIGGMSGK SKNSSDSDSK SIEGNRSADD RDLSSASSVT FASQQPSSST LSFAIPLKQD  360
PSSDYWSNIF GYNPSQNNTK NPTTVSVAPS SSLFQSRAIG SYGNNSSPIP FNMDFSSTFS  420
TSASETNNGY FGNFNIDGQQ HQEQLQHHQH EQSTITGSGS IPFATPIASN SNNGYETSSG  480
YGSWIAPSIH TFQTHAKTNL FQTPIFGME
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Present in inflorescence meristem and later in young floral mersitems. Expressed in sepal, petal, stamen and carpel primordia. In petal, progressively confined to petal margin and epidermal cells. Restricted to sporogenous tissue in the stamen and to the medial ridge of the carpel. Present in tissues that develop from this ridge, such as placenta and ovule primordia. In ovules, first expressed in distal part of the funiculus and the outer integument, before being confined to the funiculus. {ECO:0000269|PubMed:15988559}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves. {ECO:0000269|PubMed:15988559}.
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Involved in the regulation of floral organs size. {ECO:0000250, ECO:0000269|PubMed:15988559}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028946884.10.0AP2-like ethylene-responsive transcription factor AIL5
SwissprotQ6PQQ31e-151AIL5_ARATH; AP2-like ethylene-responsive transcription factor AIL5
TrEMBLA0A498IAV20.0A0A498IAV2_MALDO; Uncharacterized protein
STRINGXP_008360516.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF125622735
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G57390.11e-139AINTEGUMENTA-like 5
Publications ? help Back to Top
  1. Todd J,Post-Beittenmiller D,Jaworski JG
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.
    Plant J., 1999. 17(2): p. 119-30
    [PMID:10074711]
  2. Molitor AM,Bu Z,Yu Y,Shen WH
    Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes.
    PLoS Genet., 2014. 10(1): p. e1004091
    [PMID:24465219]
  3. Feng J,Chen D,Berr A,Shen WH
    ZRF1 Chromatin Regulators Have Polycomb Silencing and Independent Roles in Development.
    Plant Physiol., 2016. 172(3): p. 1746-1759
    [PMID:27630184]
  4. Santuari L, et al.
    The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.
    Plant Cell, 2016. 28(12): p. 2937-2951
    [PMID:27920338]
  5. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]