PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000138853
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ARF
Protein Properties Length: 271aa    MW: 30263.2 Da    PI: 5.6183
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000138853genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B366.73.4e-21150239185
                    EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE- CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkld 85 
                    f k+ltpsd++++g +++pk+ a+e+       ++++   ++l+ +d++g +W +++ yr++++r++lt+ W+ Fv a++L +gD ++F ++
  MDP0000138853 150 FSKTLTPSDTSTHGGFSVPKRIADECfppldmsQQPPV--QDLVAKDLQGYEWHFRHVYRGQPKRHLLTNDWSTFVAAKRLVAGDACIFART 239
                    88*****************************7544444..48***********************************************943 PP
2Auxin_resp21.78.8e-092382681848
     Auxin_resp  18 rastseFvvkvekvekalkvkvsvGmRfkma 48 
                    r+s++ F+ ++++++++ ++  s+GmRfkm 
  MDP0000138853 238 RTSPAAFILPFDQYMESAEIDNSIGMRFKML 268
                    899***************************5 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.83E-33142243IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.103.0E-34145243IPR015300DNA-binding pseudobarrel domain
CDDcd100177.26E-20148236No hitNo description
SMARTSM010191.3E-14150251IPR003340B3 DNA binding domain
PROSITE profilePS5086310.884150252IPR003340B3 DNA binding domain
PfamPF023629.1E-19150239IPR003340B3 DNA binding domain
PfamPF065075.6E-5237267IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 271 aa     Download sequence    Send to blast
MALRTAGVEG LPYTTSVNAR ESSGCTDAAA APAANNNQGE KDDLYHQLWL SCAGANVYIS  60
RPGEKVFYFL QGHMEQVEAY ANQDGKLEMP RYNLPSKILC NVVSVQLKAE AHTDEVYARI  120
TLLPVIEEDQ LSVEEENTPT LPRRTSTRSF SKTLTPSDTS THGGFSVPKR IADECFPPLD  180
MSQQPPVQDL VAKDLQGYEW HFRHVYRGQP KRHLLTNDWS TFVAAKRLVA GDACIFARTS  240
PAAFILPFDQ YMESAEIDNS IGMRFKMLNL L
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A2e-79332383212Auxin response factor 1
4ldw_A2e-79332383212Auxin response factor 1
4ldw_B2e-79332383212Auxin response factor 1
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expression increases during floral development. Expressed during ovary development with the highest expression on the third day after the flower fully opened. {ECO:0000269|PubMed:21735233}.
UniprotTISSUE SPECIFICITY: Expressed in root, leaf and stem (PubMed:26716451, PubMed:21735233). Also expressed in flower and fruit (PubMed:26716451). Expressed in flower buds about three days before opening including stamen, petal and sepal with the highest in ovary (PubMed:21735233). {ECO:0000269|PubMed:21735233, ECO:0000269|PubMed:26716451}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor. Involved in the control of fruit ripening process. Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26716451, PubMed:26959229). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression is up-regulated by plant hormone auxin in tomato fruits. {ECO:0000269|PubMed:26716451}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028954742.10.0LOW QUALITY PROTEIN: auxin response factor 2
SwissprotK4DF015e-82ARF2B_SOLLC; Auxin response factor 2B
TrEMBLA0A498K3A31e-149A0A498K3A3_MALDO; Auxin response factor
STRINGXP_008368914.11e-146(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF131052329
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.31e-78auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]