PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000145953
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family WRKY
Protein Properties Length: 254aa    MW: 28811.1 Da    PI: 7.37
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000145953genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY94.67.1e-30130187258
                    --SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS CS
           WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnh 58 
                    +D ++WrKYGqK++kgs++prsYYrC+s+ gC+++k+vers ++p++++itY+ eHnh
  MDP0000145953 130 SDVWAWRKYGQKPIKGSPHPRSYYRCSSSkGCSARKQVERSCSNPETFIITYTAEHNH 187
                    79*************************998**************************** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.806.2E-30115190IPR003657WRKY domain
PROSITE profilePS5081132.902124190IPR003657WRKY domain
SuperFamilySSF1182903.01E-25127190IPR003657WRKY domain
SMARTSM007745.1E-33129189IPR003657WRKY domain
PfamPF031062.6E-25131187IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 254 aa     Download sequence    Send to blast
MENWDLQAVV RGCNTDIDEV MEDSQIPYFF APLSLQEDDE LFQAYFPQAF EATTTLAELE  60
ELYKPFYPVN QITSPPTILA SSISVPQEVI TEAPKLIKNM KESAPICKRI SRKNQNKRVX  120
KEVKAEDLFS DVWAWRKYGQ KPIKGSPHPR SYYRCSSSKG CSARKQVERS CSNPETFIIT  180
YTAEHNHVHP TRRNSLAGST RSKFPSSRNK DKCSSSSNSP ATPNLAASIE DNREFVESAD  240
INIVKEEAKF LERG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-181271901577Probable WRKY transcription factor 4
2lex_A2e-181271901577Probable WRKY transcription factor 4
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.302311e-151leaf
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Activates WRKY 22, SIRK and its own promoters. {ECO:0000269|PubMed:11875555}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced 30 minutes after flagellin treatment. {ECO:0000269|PubMed:11875555}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU0136831e-112GU013683.1 Malus x domestica transcription factor WRKY (WRKY) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008363282.20.0probable WRKY transcription factor 29
SwissprotQ9SUS19e-56WRK29_ARATH; Probable WRKY transcription factor 29
TrEMBLA0A498I4Q70.0A0A498I4Q7_MALDO; Uncharacterized protein
STRINGXP_008363282.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62173150
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G23550.11e-52WRKY family protein
Publications ? help Back to Top
  1. Zhou F, et al.
    High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression.
    Plant J., 2004. 39(6): p. 920-32
    [PMID:15341634]
  2. Liu XQ, et al.
    OsWRKY03, a rice transcriptional activator that functions in defense signaling pathway upstream of OsNPR1.
    Cell Res., 2005. 15(8): p. 593-603
    [PMID:16117849]
  3. Singh V,Roy S,Singh D,Nandi AK
    Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes.
    J. Biosci., 2014. 39(1): p. 119-26
    [PMID:24499796]
  4. Yi SY,Shirasu K,Moon JS,Lee SG,Kwon SY
    The activated SA and JA signaling pathways have an influence on flg22-triggered oxidative burst and callose deposition.
    PLoS ONE, 2014. 9(2): p. e88951
    [PMID:24586453]
  5. Cambiagno DA,Lonez C,Ruysschaert JM,Alvarez ME
    The synthetic cationic lipid diC14 activates a sector of the Arabidopsis defence network requiring endogenous signalling components.
    Mol. Plant Pathol., 2015. 16(9): p. 963-72
    [PMID:25727690]
  6. Gkizi D, et al.
    The Innate Immune Signaling System as a Regulator of Disease Resistance and Induced Systemic Resistance Activity Against Verticillium dahliae.
    Mol. Plant Microbe Interact., 2016. 29(4): p. 313-23
    [PMID:26780421]
  7. Li Y,Williams B,Dickman M
    Arabidopsis B-cell lymphoma2 (Bcl-2)-associated athanogene 7 (BAG7)-mediated heat tolerance requires translocation, sumoylation and binding to WRKY29.
    New Phytol., 2017. 214(2): p. 695-705
    [PMID:28032645]
  8. Wang S, et al.
    Bacillus cereus AR156 Activates Defense Responses to Pseudomonas syringae pv. tomato in Arabidopsis thaliana Similarly to flg22.
    Mol. Plant Microbe Interact., 2018. 31(3): p. 311-322
    [PMID:29090631]