PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000184294
Common Namemads13
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MIKC_MADS
Protein Properties Length: 232aa    MW: 26839.2 Da    PI: 8.4234
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000184294genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF90.31e-28959151
                   S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
         SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                   k ien++nrqvt+skRrngi+KKA+EL vLCda+v++i++s+t+k++ey+s
  MDP0000184294  9 KLIENQTNRQVTYSKRRNGIFKKAQELTVLCDAKVSLIMLSNTNKMHEYIS 59
                   569**********************************************86 PP
2K-box79.39.4e-2771163193
          K-box   1 yqkssgksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenka 93 
                    yqk+ g +l+ +++es++  l kLk+ +++L+re+R++lG dL+ Ls+ eL +L +++++sl  iR++K++++++q+e+++kk k+l+++  +
  MDP0000184294  71 YQKTMGIDLWRTHEESMKDTLWKLKEINNKLRREIRQRLGHDLNGLSFDELASLDDEMQSSLDAIRQRKYHVIKTQTETTKKKVKNLEQRRGN 163
                    78999999*******************************************************************************998755 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004321.6E-39160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006631.188161IPR002100Transcription factor, MADS-box
SuperFamilySSF554552.62E-35295IPR002100Transcription factor, MADS-box
CDDcd002651.12E-37280No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PRINTSPR004045.3E-26323IPR002100Transcription factor, MADS-box
PfamPF003194.6E-231157IPR002100Transcription factor, MADS-box
PRINTSPR004045.3E-262338IPR002100Transcription factor, MADS-box
PRINTSPR004045.3E-263859IPR002100Transcription factor, MADS-box
PfamPF014867.0E-1982164IPR002487Transcription factor, K-box
PROSITE profilePS5129714.09484177IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 232 aa     Download sequence    Send to blast
MGRGKIEIKL IENQTNRQVT YSKRRNGIFK KAQELTVLCD AKVSLIMLSN TNKMHEYISP  60
TTTTKSMYDD YQKTMGIDLW RTHEESMKDT LWKLKEINNK LRREIRQRLG HDLNGLSFDE  120
LASLDDEMQS SLDAIRQRKY HVIKTQTETT KKKVKNLEQR RGNMLHGYFD QEAAGEDPQY  180
GYEDNEGDYE SALALSNGAN NLYTFHLHHP NLHHGGSSLG SSITHLHDLR LA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A5e-15159159MEF2C
5f28_B5e-15159159MEF2C
5f28_C5e-15159159MEF2C
5f28_D5e-15159159MEF2C
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed during flower development in stamens, petals and carpels (PubMed:17920788). Expressed in fruits and seeds (PubMed:17920788). {ECO:0000269|PubMed:17920788}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in flower development. {ECO:0000250|UniProtKB:Q0HA25}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ2511160.0AJ251116.1 Malus domestica mRNA for B-type MADS box protein (mads13 gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001315678.11e-172floral homeotic protein DEFICIENS-like
SwissprotQ003J21e-107TM6_VITVI; Agamous-like MADS-box protein TM6
TrEMBLQ8VWZ41e-171Q8VWZ4_MALDO; B-type MADS box protein
STRINGXP_008344258.11e-173(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF27353375
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G54340.12e-63MIKC_MADS family protein
Publications ? help Back to Top
  1. van der Linden CG,Vosman B,Smulders MJ
    Cloning and characterization of four apple MADS box genes isolated from vegetative tissue.
    J. Exp. Bot., 2002. 53(371): p. 1025-36
    [PMID:11971914]
  2. Jaillon O, et al.
    The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla.
    Nature, 2007. 449(7161): p. 463-7
    [PMID:17721507]
  3. Díaz-Riquelme J,Lijavetzky D,Martínez-Zapater JM,Carmona MJ
    Genome-wide analysis of MIKCC-type MADS box genes in grapevine.
    Plant Physiol., 2009. 149(1): p. 354-69
    [PMID:18997115]
  4. Grimplet J,Martínez-Zapater JM,Carmona MJ
    Structural and functional annotation of the MADS-box transcription factor family in grapevine.
    BMC Genomics, 2016. 17: p. 80
    [PMID:26818751]