PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000206676
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family AP2
Protein Properties Length: 360aa    MW: 40448.7 Da    PI: 8.0125
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000206676genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP240.66.3e-1368127155
            AP2   1 sgykGVrwdkkrgrWvAeIrd.pseng...kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                    s+++ V++++++gr++A+++d  s+n    k+ k+++lg ++ +e Aa+a++ a+ k++g
  MDP0000206676  68 SRFRAVSRHRWTGRFEAHLWDkLSWNStqkKKgKQVYLGAYDEEESAARAYDLAAVKYWG 127
                    68999****************888888886448************************998 PP
2AP233.31.2e-101541991555
            AP2  15 WvAeIrdpse...ng..krkrfslgkfgtaeeAakaaiaarkkleg 55 
                    ++A++r  s+   +g   +k+ +lg++gt eeAa+a++ a+ +++g
  MDP0000206676 154 YLASLRRKSSgfsRGvpGNKYLYLGTYGTQEEAARAYDIAAIEYRG 199
                    7788888444476678888*************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000184.39E-1768137No hitNo description
PfamPF008474.8E-1068127IPR001471AP2/ERF domain
SuperFamilySSF541712.35E-1468137IPR016177DNA-binding domain
PROSITE profilePS5103218.3669135IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.109.6E-1469136IPR001471AP2/ERF domain
SMARTSM003809.0E-2169141IPR001471AP2/ERF domain
PROSITE profilePS5103213.314124207IPR001471AP2/ERF domain
SMARTSM003805.0E-11159213IPR001471AP2/ERF domain
PfamPF008471.8E-6167199IPR001471AP2/ERF domain
SuperFamilySSF541711.18E-10170209IPR016177DNA-binding domain
CDDcd000185.11E-13171209No hitNo description
Gene3DG3DSA:3.30.730.102.3E-11172208IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 360 aa     Download sequence    Send to blast
MEFMMVRNEE NAGRCRLRTA DPEAQAARCV KRRRRDPPAV GGNSQTEQQL AQKPADQASA  60
ATTVKRSSRF RAVSRHRWTG RFEAHLWDKL SWNSTQKKKG KQVYLGAYDE EESAARAYDL  120
AAVKYWGAST FTNFPISDYD NEIEIMQSMT KEEYLASLRR KSSGFSRGVP GNKYLYLGTY  180
GTQEEAARAY DIAAIEYRGI NAVTNFDLSS YIRWLKPRAD DMIASQQVPE AVIKPKNTPF  240
AXSSYMTTEQ SPFSLTNPFA SDYVHSPRKQ EVIRTSKSSS PTALGLLLQS SVFRDLVQKN  300
SSFSDDDSID GEEPRNQLQA GRDDEFGGII YDGVGGSPFV CSSNTDENFT WNSFTSLIFA
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Present in inflorescence meristem and later in young floral mersitems. Expressed in sepal, petal, stamen and carpel primordia. In petal, progressively confined to petal margin and epidermal cells. Restricted to sporogenous tissue in the stamen and to the medial ridge of the carpel. Present in tissues that develop from this ridge, such as placenta and ovule primordia. In ovules, first expressed in distal part of the funiculus and the outer integument, before being confined to the funiculus. {ECO:0000269|PubMed:15988559}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves. {ECO:0000269|PubMed:15988559}.
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Involved in the regulation of floral organs size. {ECO:0000250, ECO:0000269|PubMed:15988559}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028953515.10.0AP2-like ethylene-responsive transcription factor At1g79700
SwissprotQ6PQQ35e-65AIL5_ARATH; AP2-like ethylene-responsive transcription factor AIL5
TrEMBLA0A498HJP00.0A0A498HJP0_MALDO; Uncharacterized protein
STRINGXP_008341750.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF21983283
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G54320.36e-68AP2 family protein
Publications ? help Back to Top
  1. Todd J,Post-Beittenmiller D,Jaworski JG
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.
    Plant J., 1999. 17(2): p. 119-30
    [PMID:10074711]
  2. Molitor AM,Bu Z,Yu Y,Shen WH
    Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes.
    PLoS Genet., 2014. 10(1): p. e1004091
    [PMID:24465219]
  3. Feng J,Chen D,Berr A,Shen WH
    ZRF1 Chromatin Regulators Have Polycomb Silencing and Independent Roles in Development.
    Plant Physiol., 2016. 172(3): p. 1746-1759
    [PMID:27630184]
  4. Santuari L, et al.
    The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.
    Plant Cell, 2016. 28(12): p. 2937-2951
    [PMID:27920338]
  5. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]