PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000211931
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family AP2
Protein Properties Length: 507aa    MW: 56198.9 Da    PI: 7.1011
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000211931genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP233.79.3e-11225281155
            AP2   1 sgykGVrwdkkrgrWvAeIrd.pseng...krkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s y+GV++++++gr++A+++d  +       rk  + g ++ +++Aa+a++ a++k++g
  MDP0000211931 225 SIYRGVTRHRWTGRYEAHLWDnSCR-RegqARKGRQ-GGYDKEDKAARAYDLAALKYWG 281
                    57*******************4444.2344336655.7799999*************98 PP
2AP249.98e-16324375155
            AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                    s y+GV++++++grW A+I  +     +k  +lg+f t+eeAa+a++ a+ k++g
  MDP0000211931 324 SIYRGVTRHHQQGRWQARIGRVAG---NKDLYLGTFATEEEAAEAYDIAAIKFRG 375
                    57****************988532...5************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.11E-14225291IPR016177DNA-binding domain
CDDcd000183.41E-19225291No hitNo description
PfamPF008471.7E-8225281IPR001471AP2/ERF domain
SMARTSM003805.7E-22226295IPR001471AP2/ERF domain
PROSITE profilePS5103217.346226289IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.104.1E-12226290IPR001471AP2/ERF domain
PRINTSPR003674.1E-6227238IPR001471AP2/ERF domain
SuperFamilySSF541719.15E-18324384IPR016177DNA-binding domain
CDDcd000182.28E-11324383No hitNo description
PfamPF008473.4E-10324375IPR001471AP2/ERF domain
SMARTSM003807.9E-31325389IPR001471AP2/ERF domain
PROSITE profilePS5103219.111325383IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.104.5E-18325383IPR001471AP2/ERF domain
PRINTSPR003674.1E-6365385IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 507 aa     Download sequence    Send to blast
MAPASNWLSF SLMSPMEMLR SSESDQSPFV PYDASSAASP HYFLDNFYAN NGWPTNPKSQ  60
VFFADGEDQS KQQGQSXSPN LSPFVDPQSH TQHIPKLEDF LGDSSSMLHL LRRRPAPAPE  120
PXQQQEDLKA ITGFQAFSTN SGSEVDSASM ARTTQQQQLS CTEFAGHSIE STGXELGVYN  180
SSCAANALSL GVTTTQSSSD QKKAIVAVDX DGSKKIADTF GQRTSIYRGV TRHRWTGRYE  240
AHLWDNSCRR EGQARKGRQG GYDKEDKAAR AYDLAALKYW GPTATTNFPV STYXKELEDM  300
KHVTKQEFIA SLRRKSSGFS RGASIYRGVT RHHQQGRWQA RIGRVAGNKD LYLGTFATEE  360
EAAEAYDIAA IKFRGINAVT NFEMNRYDVE AIGKSSLPVG GAAKRLKLSL EAEEQKPSVS  420
HDQQHPQCSS GNNINFTSMQ PVQSIPCGIP YDAAAANAYY HNLFHQFQPN YYGALDSAGL  480
NPNIATQMNM MPQQPAEFYI WPNHQSH
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.260300.0bud| root
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Detected in inflorescence and youg floral mersitems, and in stem procambial cells. In floral mersitems, mostly expressed in the central dome. Disappears progressively from sepal primordia, but accumulates in second, third and fourth whorl organ primordia. Later, confined to occasional patches in stamens and in petal before disparearing progressively from flowers. {ECO:0000269|PubMed:15988559}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings, hypocotyl, inflorescence, siliques, and pistils. Also detected at low levels in leaves. {ECO:0000269|PubMed:15988559, ECO:0000269|PubMed:16307362}.
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028943621.10.0AP2-like ethylene-responsive transcription factor AIL6
RefseqXP_028943666.10.0AP2-like ethylene-responsive transcription factor AIL6
SwissprotQ52QU21e-180AIL6_ARATH; AP2-like ethylene-responsive transcription factor AIL6
TrEMBLA0A498KJK50.0A0A498KJK5_MALDO; Uncharacterized protein
STRINGXP_008338468.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF48103149
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G10510.21e-177AINTEGUMENTA-like 6
Publications ? help Back to Top
  1. Krizek BA
    Intronic sequences are required for AINTEGUMENTA-LIKE6 expression in Arabidopsis flowers.
    BMC Res Notes, 2015. 8: p. 556
    [PMID:26459062]
  2. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  3. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  4. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]