PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000215359
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB
Protein Properties Length: 485aa    MW: 55103.1 Da    PI: 6.9747
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000215359genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding61.32.1e-19215261148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g WTteEd ll+++v+q+G + W+ Ia++++ gR +kqc++rw+++l
    MDP0000215359 215 KGQWTTEEDRLLIQLVEQFGVRKWSHIAQMLP-GRIGKQCRERWHNHL 261
                      799*****************************.*************97 PP
2Myb_DNA-binding574.5e-18267309145
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 
                      ++ W++eEd+ l++a+++ G++ W+ Ia++++ gRt++++k++w+
    MDP0000215359 267 KDTWSEEEDKTLIQAHAEIGNK-WAEIAKRLP-GRTENSIKNHWN 309
                      679*******************.*********.***********8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129430.554210265IPR017930Myb domain
SuperFamilySSF466894.67E-32212308IPR009057Homeodomain-like
SMARTSM007174.2E-18214263IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.8E-27216267IPR009057Homeodomain-like
CDDcd001671.14E-16218261No hitNo description
PfamPF139214.7E-20218278No hitNo description
SMARTSM007172.8E-17266314IPR001005SANT/Myb domain
PROSITE profilePS5129421.694266316IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.2E-22268314IPR009057Homeodomain-like
CDDcd001671.65E-13269312No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010183Biological Processpollen tube guidance
GO:0045697Biological Processregulation of synergid differentiation
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 485 aa     Download sequence    Send to blast
MELNKLRKKL VSQIHIPLFA SENYVKPYAM KDEFLFETSS SSKRNYNYLQ DFHHLDHQFH  60
VNVSSSNPMF GTHTPCFDPY SDTSYPYDQN SSHQDVNFYK CKPPNVAENN GGHGQVLDNF  120
QGGSYLNFPT HHRSSNPFDH AVGTSSHGSA TNFLPLDCTQ DIKPMNFSVP DEVSCINNAD  180
QNGYYRKFGM NGKSKVTGVT RGSMVKGRKK SNVVKGQWTT EEDRLLIQLV EQFGVRKWSH  240
IAQMLPGRIG KQCRERWHNH LRPDIKKDTW SEEEDKTLIQ AHAEIGNKWA EIAKRLPGRT  300
ENSIKNHWNA TKRRQYSKRK CRSKYPRGSI LQEYIKSLNL DSASNSTGRQ RRNSSANNNN  360
GGSTSTKAAA AAATYQQPQT NVGLLCANDL LVPSYNDFNE DPDFCFDENI FEEGCSIDSL  420
LDDIPCAAAV GEKNSNFDGY NEIDYGYVDK GNFDEKDFQM AMQVDLESNE VKKEMDLVEM  480
ISQVN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1mse_C1e-452133152104C-Myb DNA-Binding Domain
1msf_C1e-452133152104C-Myb DNA-Binding Domain
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in cellularized but not uncellularized female gametophytes. {ECO:0000269|PubMed:16214903}.
UniprotTISSUE SPECIFICITY: Expressed at high levels in the synergid cells of the female gametophyte, and at lower levels in the endosperm of young seeds and the trichomes of young leaves and sepals. {ECO:0000269|PubMed:16214903, ECO:0000269|PubMed:17693534}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to the motif 5'-GTAACNT-3' in the promoter of target genes (e.g. DD11 and DD18) and promotes their expression within synergid cells (e.g. in the filiform apparatus) in ovules (PubMed:16214903, PubMed:17693534, PubMed:18410484, PubMed:17937500). Required for the formation of the filiform apparatus during synergid cell differentiation in the female gametophyte (PubMed:16214903). Involved in pollen tube guidance to the micropyle (PubMed:16214903, PubMed:17937500, PubMed:23093426). {ECO:0000269|PubMed:16214903, ECO:0000269|PubMed:17693534, ECO:0000269|PubMed:17937500, ECO:0000269|PubMed:18410484, ECO:0000269|PubMed:23093426}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00442DAPTransfer from AT4G18770Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008374889.10.0transcription factor MYB98-like
SwissprotQ9S7L21e-100MYB98_ARATH; Transcription factor MYB98
TrEMBLA0A498JKG50.0A0A498JKG5_MALDO; Uncharacterized protein
STRINGXP_008374889.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF15703196
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G18770.13e-98myb domain protein 98
Publications ? help Back to Top
  1. Mendes MA, et al.
    Live and let die: a REM complex promotes fertilization through synergid cell death in Arabidopsis.
    Development, 2016. 143(15): p. 2780-90
    [PMID:27338615]